Patents by Inventor John Gerster

John Gerster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080091010
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are disclosed.
    Type: Application
    Filed: December 6, 2007
    Publication date: April 17, 2008
    Applicant: Graceway Pharmaceuticals, LLC
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Publication number: 20070259881
    Abstract: Imidazo ring systems, which include, for example, imidazopyridine, imidazoquinoline, 6,7,8,9-tetrahydroimidazoquinoline, imidazonaphthyridine, and 6,7,8,9-tetrahydroimidazonaphthyridine compounds substituted at the 1-position and/or the 2-position, pharmaceutical compositions containing these compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
    Type: Application
    Filed: June 17, 2005
    Publication date: November 8, 2007
    Inventors: Joseph Dellaria, Tushar Kshirsagar, Shri Niwas, William Moser, Joan Moseman, Kyle Lindstrom, Azim Celebi, John Gerster, Philip Heppner, Joshua Wurst
  • Publication number: 20060128674
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are disclosed.
    Type: Application
    Filed: February 13, 2006
    Publication date: June 15, 2006
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Publication number: 20060111387
    Abstract: Aryl substituted imidazoquinoline compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral, and neoplastic, are disclosed.
    Type: Application
    Filed: January 13, 2006
    Publication date: May 25, 2006
    Inventors: David Hays, Tushar Kshirsagar, Philip Heppner, Bryon Merrill, Michael Danielson, John Gerster, Chad Haraldson, Sarah Johannessen, Maureen Kavanagh, Kyle Lindstrom, Michael Rice, David Squire, Sarah Strong, Joshua Wurst
  • Publication number: 20060100229
    Abstract: Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, and 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.
    Type: Application
    Filed: April 1, 2005
    Publication date: May 11, 2006
    Inventors: David Hays, Michael Danielson, John Gerster, Shri Niwas, Ryan Prince, Tushar Kshirsagar, Philip Heppner, William Moser, Joan Moseman, Matthew Radmer, Maureen Kavanagh, Sarah Strong, Jason Bonk
  • Publication number: 20050288320
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: July 25, 2005
    Publication date: December 29, 2005
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalek, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Publication number: 20050107421
    Abstract: Imidazonaphthyridine and tetrahydroimidazonaphthyridine compounds induce the biosynthesis of cytokines such as interferon and tumor necrosis factor. The compounds exhibit antiviral and antitumor properties. Methods of preparing the compounds and intermediates useful in the preparation of the compounds are also disclosed.
    Type: Application
    Filed: December 3, 2004
    Publication date: May 19, 2005
    Inventors: John Gerster, Kyle Lindstrom, Stephen Crooks, Philip Heppner, Gregory Marszalck, Peter Maye, Bryon Merrill, John Mickelson, Michael Rice
  • Publication number: 20050096470
    Abstract: A process for preparing 1H-imidazo[4,5-c]quinolin-4-amines is disclosed. The process involves reacting a 6H-imidazo[4,5-c]tetrazolo[1,5-a]quinoline with triphenylphosphine and hydrolyzing the product thereof.
    Type: Application
    Filed: October 27, 2004
    Publication date: May 5, 2005
    Inventors: John Gerster, Kyle Lindstrom
  • Publication number: 20050026943
    Abstract: Thiazolo-, oxazolo- and selenazolo[4,5-c]quinolin-4-amines and analogs thereof are described including methods of manufacture and the use of novel intermediates. The compounds are immunomodulators and induce cytokine biosynthesis, including interferon and/or tumor biosynthesis, necrosis factor, and inhibit the T-helper-type 2 immune response. The compounds are further useful in the treatment of viral and neoplastic diseases.
    Type: Application
    Filed: August 25, 2004
    Publication date: February 3, 2005
    Inventors: John Gerster, Kyle Lindstrom, Gregory Marszalek, Michael Rice