Patents by Inventor John Ghraveb

John Ghraveb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating rheumatoid arthritis by multiple administration of anti-TNF antibodies
    Patent number: 7179466
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-? (TNF?) and are useful in vivo diagnosis and therapy of a number of TNF?-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: February 20, 2007
    Assignees: New York University, Centocor, Inc.
    Inventors: Junming Le, Jan Vilcek, Peter Daddona, John Ghraveb, David Knight, Scott Siegel
  • Anti-TNF antibodies and peptides of human tumor necrosis factor
    Publication number: 20040138427
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-&agr; (TNF&agr;) and are useful in vivo diagnosis and therapy of a number of TNF&agr;-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: February 6, 2004
    Publication date: July 15, 2004
    Applicants: Centocor, Inc., New York University
    Inventors: Junming Le, Jan Vilcek, Peter Daddona, John Ghraveb, David Knight, Scott Siegel
  • Methods of treating ulcerative colitis with chimeric anti-TNF antibodies
    Publication number: 20030198641
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-&agr; (TNF&agr;) and are useful in vivo diagnosis and therapy of a number of TNF&agr;-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: March 4, 2003
    Publication date: October 23, 2003
    Applicants: New York University, Centocor, Inc.
    Inventors: Junming Le, Jan Vilcek, Peter Daddona, John Ghraveb, David Knight, Scott Siegel
  • Methods of treating vascular inflammatory pathology by multiple administration of chimeric anti-TNF antibodies
    Publication number: 20030181695
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-&agr; (TNF&agr;) and are useful in vivo diagnosis and therapy of a number of TNF&agr;-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: February 21, 2003
    Publication date: September 25, 2003
    Applicant: New York University
    Inventors: Junming Le, Jan Vilcek, Peter Daddona, John Ghraveb, David Knight, Scott Siegel
  • Methods of treatment by multiple administration of chimeric anti-TNF antibodies
    Publication number: 20030175275
    Abstract: Anti-TNF antibodies, fragments and regions thereof which are specific for human tumor necrosis factor-&agr; (TNF&agr;) and are useful in vivo diagnosis and therapy of a number of TNF&agr;-mediated pathologies and conditions, as well as polynucleotides coding for murine and chimeric antibodies, methods of producing the antibody, methods of use of the anti-TNF antibody, or fragment, region or derivative thereof, in immunoassays and immunotherapeutic approaches are provided.
    Type: Application
    Filed: June 28, 2002
    Publication date: September 18, 2003
    Applicant: New York University
    Inventors: Junming Le, Jan Vilcek, Peter Daddona, John Ghraveb, David Knight, Scott Siegel