Abstract: Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram).

Abstract: An independent rear wheel suspension system having top and bottom parallel struts which are linked to a control arm and which make each rear wheel produce predetermined cornering toe alignment with no effective change to the camber angle of the wheels. The angle of the struts at rest as viewed in reference to a leveled ground plane is used to predetermine the wheels' toe change during cornering. The limits of wheels' toe change are conditional to the spring rate acting on each rear wheel. The camber angle and the cornering toe alignment of the wheels can be adjusted independently from each other.