Abstract: The present invention relates to a method of preparing a topical pharmaceutical composition, a pharmaceutical composition prepared by the method, a topical pharmaceutical composition, and to uses and methods involving the pharmaceutical composition. The pharmaceutical composition comprises at least one local anesthetic agent and a vasoconstrictive agent. The method of preparing the composition comprises stirring an aqueous liquid comprising at least one local anesthetic agent and a vasoconstrictive agent, wherein the stirring is performed substantially without forming a vortex and under an inert gas. The at least one local anesthetic agent may be lignocaine and tetracaine, and the vasoconstrictive agent may be adrenaline.

Abstract: A system is provided for controlling operation of an electrically controlled and magnetically actuated locking web retractor of an occupant restraint coupled to an occupant seat of a motor vehicle. A control circuit may monitor output signals produced by one or more sensors configured to produce one or more respective sensor output signals indicative of one or more corresponding sensed conditions of the motor vehicle, vehicle seat or occupant restraint, process the output signals produced by the one or more sensors to determine one or more values of the one or more sensed conditions, compare the one or more determined values of the one or more sensed conditions to one or more corresponding threshold or range values, and then provide a control signal, based on the one or more comparisons, to a magnet actuator of the web retractor to cause the web retractor to lock or unlock.

Abstract: A system is provided for controlling operation of an electrically controlled and magnetically actuated locking web retractor of an occupant restraint coupled to an occupant seat of a motor vehicle. A control circuit may monitor output signals produced by one or more sensors configured to produce one or more respective sensor output signals indicative of one or more corresponding sensed conditions of the motor vehicle, vehicle seat or occupant restraint, process the output signals produced by the one or more sensors to determine one or more values of the one or more sensed conditions, compare the one or more determined values of the one or more sensed conditions to one or more corresponding threshold or range values, and then provide a control signal, based on the one or more comparisons, to a magnet actuator of the web retractor to cause the web retractor to lock or unlock.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: Structured elements with capabilities for stream flow division and distribution and mitigation of undesired species that exceed those of conventionally available materials are provided. The structured elements provide increased opportunities for surface attraction, retention and coalescence of undesired species in a process stream. The functional contact surfaces of the structured elements can include one or more of the faces of cells, the surfaces of struts connecting cells, the surfaces of nodes connecting struts, and the surfaces of asperities or irregularities caused by channels, flutes, spikes, fibrils or filaments in or on the material surfaces.

Abstract: A process of making micro-sized protein particles comprising the step of drying nano-sized protein particles suspended in a liquid medium under conditions to agglomerate the nano-sized protein particles and thereby form micro-sized protein particles.

Abstract: A process of making micro-sized protein particles comprising the step of drying nano-sized protein particles suspended in a liquid medium under conditions to agglomerate the nano-sized protein particles and thereby form micro-sized protein particles.

Abstract: The present invention provides a method for controlling the partitioning of a recombinant protein between the supernatant and the periplasm in E. coli host cell cultures wherein expression of the recombinant protein by said cells is under the control of an inducible system, which method comprises: a) providing an E. coli host cell culture b) changing the growth rate of the E. coli host cells c) inducing expression of the recombinant protein wherein steps (b) and (c) can be performed in any order or simultaneously; and subsequently d) determining the yield of recombinant protein in the culture supernatant and the E. coli host cell periplasm e) comparing the yield determined in step (d) with the yield determined when at least one other growth rate has been used in step (b) f) selecting a growth rate from the comparison made in step (e) in which the partitioning of the recombinant protein between the supernatant and the periplasm is most suited to the primary recovery of the recombinant protein.

Abstract: A batch of printed credentials each including a polyoptic region including a respective image separately determined during production according to biographic or other information unique to the credential holder, as well as system and a method for producing such credentials. The respective images of the credentials in the batch may convey targeted marketing information. The production process uses credential data retrieved from a data store to print the plurality of customized credentials on a single medium where each credential on the single medium includes an image field based on dynamic data relationships of retrieved credential data.

Abstract: A batch of individualized credentials, e.g., ID tags, event tickets, etc., taken from a credential medium that includes respective polyoptic regions each carrying an encoded image set associated with respective individualized credentials, as well as a system and a method or producing the same. The production process uses credential data retrieved from a data store to create a plurality of individualized credentials on a single sheet medium. The dynamic production process enables inclusion of variable customer or patronage data, or individual object data (e.g., a serial number or object characteristic) on individual credentials using a template file that identifies a type of data to be retrieved from the data store and/or a specified image generated according to the value, nature, or type of the individualized data.

Abstract: In one aspect, the invention provides a gas treatment apparatus (1) comprising a gas-flow path and a plurality of reactor units (5)-(7) through which gas to be treated may flow arranged in series along the path. The reactor units (5)-(7) are adapted to generate a non-equilibrium plasma. This aspect of the invention may be used for decomposing pollutant materials in a gas (e.g. air). When air is being treated, the apparatus of this aspect of the invention is advantageously provided, downstream of the final reactor unit in series, with at least one catalyst bed (8) incorporating a catalyst capable of decomposing ozone.

Abstract: A batch of credentials printed on a credential medium having a pattern of lenses (e.g., lenticular or other pattern), as well as a system and method for producing such credentials. A library of encoders is used to encode pixel locations of a plurality of view sets comprising a number of individual image frames. Each view set is associated with a distinct region on a credential having distinct polyoptic properties (e.g., orientation, frequency, shape). Encoded images produced by the library of encoders are combined (e.g., by interlacing or other encoding pattern) into a single print-ready image that is aligned (e.g., registered) with lenses of the distinct polyoptic areas on a medium on which the credential is printed. Encoding may take the form of positioning, sizing, intensifying, coloring, masking, interlacing, interleaving, scrambling, mixing, transformation, alteration, translation of pixels, or a combination thereof.

Abstract: A method for removing contaminants from an process stream that includes the use of reticulated material to filter the process stream. The reticulated material also facilitate process stream flow distribution in process units. The reticulated material can be packed with a void space between a substantial number of the reticulated material that can be varied to enhance filtration and flow distribution. The method of filtering also provides a method of removing contaminants leaving process equipment. The methods can be used on a variety of process streams and process equipment. The reticulated material can include ceramics, metallic materials, and chemical vapor deposition elements. The reticulated material can be of various shapes and sizes, and can also be catalytically active.

Abstract: The present invention provides a method for controlling the partitioning of a recombinant protein between the supernatant and the periplasm in E. coli host cell cultures wherein expression of the recombinant protein by said cells is under the control of an inducible system, which method comprises: a) providing an E. coli host cell culture b) changing the growth rate of the E. coli host cells c) inducing expression of the recombinant protein wherein steps (b) and (c) can be performed in any order or simultaneously; and subsequently d) determining the yield of recombinant protein in the culture supernatant and the E. coli host cell periplasm e) comparing the yield determined in step (d) with the yield determined when at least one other growth rate has been used in step (b) f) selecting a growth rate from the comparison made in step (e) in which the partitioning of the recombinant protein between the supernatant and the periplasm is most suited to the primary recovery of the recombinant protein.

Abstract: The present invention provides a method for controlling the partitioning of a recombinant protein between the supernatant and the periplasm in E. coli host cell cultures wherein expression of the recombinant protein by said cells is under the control of an inducible system, which method comprises: a) providing an E. coli host cell culture b) changing the growth rate of the E. coli host cells c) inducing expression of the recombinant protein wherein steps (b) and (c) can be performed in any order or simultaneously; and subsequently d) determining the yield of recombinant protein in the culture supernatant and the E. coli host cell periplasm e) comparing the yield determined in step (d) with the yield determined when at least one other growth rate has been used in step (b) f) selecting a growth rate from the comparison made in step (e) in which the partitioning of the recombinant protein between the supernatant and the periplasm is most suited to the primary recovery of the recombinant protein.