Patents by Inventor John Gottsch

John Gottsch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation and cryopreservation of pluripotent stem cell-derived clinical grade corneal endothelial cells
    Patent number: 12553027
    Abstract: Human embryonic stem cell (hESC)- and induced pluripotent stem cell (iPSC)-derived clinical-grade corneal endothelial cells (CECs) generation and cryopreservation through the neural crest cell (NCC) lineage using peripheral blood as a donor source and hESCs maximizes the availability of these vital cells for treating the corneal endothelial disease as an alternative to donor corneas for corneal endothelium (CE) transplantations and other applications.
    Type: Grant
    Filed: December 12, 2019
    Date of Patent: February 17, 2026
    Assignee: The Johns Hopkins University
    Inventors: S. Amer Riazuddin, John Gottsch, Shahid Khan, Muhammad Ali
  • GENERATION AND CRYOPRESERVATION OF PLURIPOTENT STEM CELL-DERIVED CLINICAL GRADE CORNEAL ENDOTHELIAL CELLS
    Publication number: 20220025325
    Abstract: Human embryonic stem cell (hESC)- and induced pluripotent stem cell (iPSC)-derived clinical-grade corneal endothelial cells (CECs) generation and cryopreservation through the neural crest cell (NCC) lineage using peripheral blood as a donor source and hESCs maximizes the availability of these vital cells for treating the corneal endothelial disease as an alternative to donor corneas for corneal endothelium (CE) transplantations and other applications.
    Type: Application
    Filed: December 12, 2019
    Publication date: January 27, 2022
    Inventors: S. Amer Riazuddin, John Gottsch, Shahid Khan, Muhammad Ali