Patents by Inventor John Graham
John Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12263307Abstract: This invention relates to a medical tube comprises an elongate conduit having a first opening, a second opening, a longitudinal axis, a lumen extending between the first opening and the second opening along the longitudinal axis, and a corrugated wall, formed from an extruded material, extending between the first opening and the second opening and surrounding the lumen. The wall is stiffer in a first length of the conduit adjacent the first opening than in a second length of the conduit adjacent the second opening. The variable stiffness of the tube wall can improve the thermal profile of the tube as well as improve drain-back of condensation into a humidifier providing humidified gas to the tube.Type: GrantFiled: September 22, 2020Date of Patent: April 1, 2025Assignee: FISHER & PAYKEL HEALTHCARE LIMITEDInventors: Peter Kenneth Graham, Enrico Alvarez Garcia, David John Sims
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Patent number: 12263549Abstract: Typically, fluids used in fracking operations erode valve seats in the fluid end of the reciprocating pump. Thus, these valve seats must frequently be replaced by new valve seats. Accordingly, a remanufacturing process is disclosed that successively cleans and/or grinds manually or mechanically at least the carbide inserts from used valve seats until the inserts are reusable. This reduces material costs and promotes efficiency and sustainability.Type: GrantFiled: August 23, 2023Date of Patent: April 1, 2025Assignee: Caterpillar Inc.Inventors: Abel Noriega, II, Curtis John Graham, Christopher Anthony Kinney, Connor J Docherty, Blake Messer
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Publication number: 20250095261Abstract: The runtime retargeting approaches discussed herein can enable real time adaptation of character and object motion. In particular, fixed-source motion can be dynamically adjusted to variable situations encountered during runtime. In this way, the runtime retargeting approaches discussed herein can preserve the intent, visual quality, and essence of such fixed-source motion, while modifying it to meet new physical constraints or goals.Type: ApplicationFiled: September 13, 2024Publication date: March 20, 2025Inventors: Eray MOLLA, Peter James SANDILANDS, James Stuart MILLER, Ahmad ABDUL KARIM, Mark William TENNANT, Frank David KOZUH, Colin John GRAHAM
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Publication number: 20250098109Abstract: An immersion cooling system and methods for operating the system are described. The system can comprise a vessel configured to hold thermally conductive, condensable dielectric fluid; a pressure controller to reduce or increase an interior pressure of the vessel; a computer component configured to be at least partially submerged within the dielectric fluid; and a fluid circulation system configured to draw the dielectric fluid from a sump area of the vessel, pass the dielectric fluid through a filter and deliver the dielectric fluid to a bath area of the vessel.Type: ApplicationFiled: June 10, 2022Publication date: March 20, 2025Inventors: EDWARD KING, Raquel PARKER, DARSHAN PATELL, RANDALL COBURN, JOSH HALEY, RYAN GRAHAM, JASON ERICKSON, JACOB MERTEL, TAYLOR MONNIG, BRIAN HAUGHT, RYAN MYRE, WILLIAM BRET BOREN, ANDREW DOWNS, DUSTIN YEATMAN, JOHN DAVID ENRIGHT, RICK MARGERISON, JIMIL M. SHAH, WILLIAM HADALA, JOSH WHITAKER, SEAMUS EGAN, BRAD FURNISH, Tim Tomlin
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Publication number: 20250082750Abstract: Methods for treating moderate-to-severe or severe atopic dermatitis in a pediatric subject are provided. In one aspect, the methods comprise administering to the subject one or more doses of an interleukin-4 receptor (IL-4R) antagonist, such as an anti-IL-4R antibody or antigen-binding fragment thereof.Type: ApplicationFiled: July 18, 2024Publication date: March 13, 2025Inventors: Ashish BANSAL, Neil GRAHAM, Paola MINA-OSORIO, John DAVIS, Mohamed KAMAL
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Patent number: 12248792Abstract: A compute server receives a request that triggers execution of a code piece out of multiple code pieces. A single process at the compute server executes the code piece, which is run in an isolated execution environment. Each other code piece runs in other isolated execution environments respectively and executed by the single process. The code piece, when executed, modifies a response to the request. The response is generated based at least in part on the executed code piece. The generated response is transmitted.Type: GrantFiled: December 21, 2023Date of Patent: March 11, 2025Assignee: CLOUDFLARE, INC.Inventors: Kenton Taylor Varda, Zachary Aaron Bloom, Marek Przemyslaw Majkowski, Ingvar Stepanyan, Kyle Kloepper, Dane Orion Knecht, John Graham-Cumming, Dani Grant
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Publication number: 20250074901Abstract: The invention provides new heteroaromatic compounds having the general formula (I?), or a solvate or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, Y1, Y2, Y3, and n are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.Type: ApplicationFiled: November 17, 2022Publication date: March 6, 2025Inventors: Mark CHAPMAN, James DAVIDSON, Nicholas Gareth Morse DAVIES, Aaron GERLACH, Christopher John GRAHAM, Sylvain LEBRETON, Ronghua LI, Nina MA, Ingrid MECHIN, David MOWREY, Karthigeyan NAGARAJAN, Anil NAIR, Roger David NORCROSS, Roger Lluis REDONDO PENA, Alena SAFAROVA, Martin SMRCINA
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Publication number: 20250065452Abstract: Typically, fluids used in fracking operations erode valve seats in the fluid end of the reciprocating pump. Thus, these valve seats must frequently be replaced by new valve seats. Accordingly, a remanufacturing process is disclosed that successively cleans and/or grinds manually or mechanically at least the carbide inserts from used valve seats until the inserts are reusable. This reduces material costs and promotes efficiency and sustainability.Type: ApplicationFiled: August 23, 2023Publication date: February 27, 2025Applicant: Caterpillar Inc.Inventors: Abel NORIEGA, II, Curtis John GRAHAM, Christopher Anthony KINNEY, Connor J DOCHERTY, Blake MESSER
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Publication number: 20250067554Abstract: A self-mixing interferometer configured to monitor particulate material within a monitored region of space comprising a laser cavity assembly (1A) and an optical assembly (1B) configured to bathe the monitored region with laser light of the interferometer. A laser monitoring unit (1C) is configured to acquire an interferometric signal generated by the interferometer in response to light returned to the laser cavity assembly from said wavefronts by said particulate material. A processing module (1D) is configured to determine a property of the particulate material within the monitored region according to a wavelet transformation of the interferometric signal at least a part of which comprises a waveform of changing frequency.Type: ApplicationFiled: December 7, 2022Publication date: February 27, 2025Inventors: David James GRAHAM, Michele BENETTI, Sanjeeb TRIPATHY, Christopher John BATEMAN, Alexander Michael KEMBER
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Publication number: 20250060297Abstract: A self-mixing interferometer configured to monitor particulate material within a monitored region of space comprising a laser cavity assembly (1A) and an optical assembly (1B) configured to bathe the monitored region with laser light of the interferometer possessing wavefronts having different directions at different respective locations within the monitored region. A laser monitoring unit (1C) is configured to acquire an interferometric signal generated by the interferometer in response to light returned to the laser cavity assembly from said wavefronts by said particulate material. A processing module (1D) is configured to determine a property of the particulate material within the monitored region according to changes in the frequency of a waveform within at least a part of the interferometric signal.Type: ApplicationFiled: December 7, 2022Publication date: February 20, 2025Inventors: David James GRAHAM, Michele BENETTI, Sanjeeb TRIPATHY, Christopher John BATEMAN, Alexander Michael KEMBER
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Publication number: 20250057670Abstract: The invention relates to an automated hand, such as a prosthetic hand. In one form, the automated hand may be fluid compatible. In one form, the automated hand may comprise features to reduce the risk of harm to motors and/or other sensitive components of the hand when subject to an impact. In one form, the hand may comprise a wrist joint configured to allow the hand to curl and flex and/or to rotate. In one form, one or more digits of the hand may be individually controlled. In one form the hand may include a thumb rotation locking mechanism. In one form the hand may be provided with removable grip plates. In one form, the hand May be configured for use as a training hand.Type: ApplicationFiled: November 1, 2024Publication date: February 20, 2025Applicant: 5th Element LimitedInventors: Mathew James JURY, David Neil LOVEGROVE, Ross Hughan DAWSON, Oliver Charles Graham JACKSON-HILL, Darryl John BEST, Jonathan David LOWY
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Publication number: 20250061907Abstract: Encoding and decoding systems are described for the provision of high quality digital representations of audio signals with particular attention to the correct perceptual rendering of fast transients at modest sample rates. This is achieved by optimising downsampling and upsampling filters to minimise the length of the impulse response while adequately attenuating alias products that have been found perceptually harmful.Type: ApplicationFiled: October 31, 2024Publication date: February 20, 2025Inventors: Peter Graham CRAVEN, John Robert STUART
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Patent number: 12226448Abstract: The present disclosure relates to improved oral immunotherapy methods for treating peanut allergy. In certain embodiments, the disclosure provides methods for continuing an oral immunotherapy for the treatment of a peanut allergy after missing a scheduled oral administration of one or more consecutive doses of a pharmaceutical composition comprising peanut protein.Type: GrantFiled: December 19, 2019Date of Patent: February 18, 2025Assignee: Société des Produits Nestlé S.A.Inventors: John Graham Matthews, Kari Rose Brown, Anoshie Ratnayake, Daniel Adelman
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Publication number: 20250052114Abstract: A dock gate barrier system includes: a barrier with first and second ends with a central axis extending therebetween, and a coupling defining a passage; and a support member, from which extends a hitch pin, which extends along a longitudinal axis, and can enter and extend into the coupling passage. The hitch pin and the passage are configured such that: in a first configuration, the hitch pin can enter into/withdraw from, the passage; and in a second configuration, in response to a load being applied to the barrier causing it to bend, the hitch pin is engaged with the coupling to thereby lock the coupling relative to the hitch pin and thereby lock the barrier member to the first support member.Type: ApplicationFiled: December 22, 2022Publication date: February 13, 2025Inventors: John Graham MARTIN, Matthew Lee SCOTHERN
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Publication number: 20250052663Abstract: A self-mixing interferometer configured to monitor particulate material within a monitored region of space comprising a laser cavity assembly (1A) and an optical assembly (1B) configured to bathe the monitored region with laser light of the interferometer. A laser monitoring unit (1C) is configured to acquire an interferometric signal generated by the interferometer in response to light returned to the laser cavity assembly from said wavefronts by said particulate material. A processing module (1D) is configured to determine a property of the particulate material within the monitored region according to a structure in data describing the interferometric signal in a frequency-space transformation thereof wherein at least a part of the interferometric signal comprises a waveform of changing frequency.Type: ApplicationFiled: December 7, 2022Publication date: February 13, 2025Inventors: David James GRAHAM, Michele BENETTI, Sanjeeb TRIPATHY, Christopher John BATEMAN, Alexander Michael KEMBER
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Patent number: 12222158Abstract: A natural gas liquid plant is retrofitted with a bolt-on unit that includes an absorber that is coupled to an existing demethanizer by refrigeration produced at least in part by compression and expansion of the residue gas, wherein ethane recovery can be increased to at least 99% and propane recovery is at least 99%, and where a lower ethane recovery of 96% is required, the bolt-on unit does not require the absorber, which could be optimum solution for revamping an existing facility. Contemplated configurations are especially advantageous to be used as bolt-on upgrades to existing plants.Type: GrantFiled: July 7, 2023Date of Patent: February 11, 2025Assignee: FLUOR TECHNOLOGIES CORPORATIONInventors: John Mak, Sabrina Devone, James Shih, Curt Graham
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Patent number: 12221439Abstract: The present disclosure relates to compounds of formula (I), which are suitable as AhR modulators, in particular AhR inhibitors. The disclosure also relates to compositions comprising said compounds and use of said compounds or compositions in treatment, in particular in the treatment of cancer. The disclosure further relates to methods of preparing said compounds.Type: GrantFiled: August 23, 2019Date of Patent: February 11, 2025Assignee: JAGUAHR THERAPEUTICS PTE LTDInventors: Antonio Mete, James Hitchin, Mark Graham, John King-Underwood, Philip Vellacott Thorne
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Publication number: 20250041620Abstract: A wearable therapy device for relieving pain and muscle's recovery, comprising a primary sheet configured with at least one slot on each side of primary sheet, each slot configured with a strap for tightening the strap with the user's body portion, a FPCB arranged in between primary sheet and secondary sheet for transmitting power to LEDs mounted on the FPCB, to illuminate, a detachable controller attached with the rear side of the primary sheet for controlling the functions, and a polarity protection circuit to alter polarity of poles.Type: ApplicationFiled: August 4, 2023Publication date: February 6, 2025Applicant: LUMAFLEX LLCInventors: Kim Markwat, Alain Dijkstra, John Graham Harper
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Patent number: 12215922Abstract: A method for removing heavy hydrocarbons from a feed gas by: feeding, into an absorber, a top reflux stream and a second reflux stream below the top reflux stream, wherein the absorber produces an absorber bottom product stream and an absorber overhead product stream; depressurizing and feeding the absorber bottom product stream to a stripper to produce a stripper bottom product stream and a stripper overhead product stream; cooling and feeding a portion of the absorber overhead product stream back to the absorber as the top reflux stream; and pressurizing and feeding the stripper overhead product stream back to the absorber as the second reflux stream. Systems for carrying out the method are also provided.Type: GrantFiled: May 23, 2019Date of Patent: February 4, 2025Assignee: Fluor Technologies CorporationInventors: John Mak, Jacob Thomas, Dhirav Patel, Curt Graham, Irene Zhang
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Patent number: D1064595Type: GrantFiled: February 11, 2022Date of Patent: March 4, 2025Assignee: OSPREY PACKS, INC.Inventors: Christopher John Graham, Cassandra Munson Tweed, Thomas Pierre Rene Tellier