Abstract: The present disclosure discusses a method of manufacturing an implantable neural electrode. The method includes cutting a metal layer to form a plurality of electrode sites, contact pads and metal traces connecting the electrode sites to the contact pads. A first silicone layer including a mesh is formed and coupled to the metal layer. A second silicone layer is formed and laminated to the first silicone layer coupled with the metal layer. Holes are formed in the first or second silicone layer exposing the contact pads and electrode sites. Wires are welded to the exposed contact pads and a third layer of silicone is overmolded over the contact pads and wires.

Abstract: The invention relates to an axial turbine with a rotating casing and stationary shaft, sections for the assembly thereof, and materials for the manufacture thereof.

Abstract: Processes and systems are provided for converting a carbonaceous feedstock into a reaction gas and a syngas, involving a step of pyrolysing and methanating the feedstock in a pyrolysis chamber to produce the reaction gas and a step of gasifying unconverted feedstock in the presence of a reactant to produce a syngas.

Abstract: A turbine assembly includes an axial turbine with an axially arranged series of rotor sections and an external sheath providing structural support for the axial turbine, wherein the sheath is made from dense silicon nitride. Each rotor section includes an outer ring and rotor blades and the outer rings of the rotor sections connect to form a rotating outer casing, wherein the rotor sections are made from reaction bonded silicon nitride.

Abstract: A turbine assembly includes an axial turbine with an axially arranged series of rotor sections and an external sheath providing structural support for the axial turbine, wherein the sheath is made from dense silicon nitride. Each rotor section includes an outer ring and rotor blades and the outer rings of the rotor sections connect to form a rotating outer casing, wherein the rotor sections are made from reaction bonded silicon nitride.

Abstract: A process for extracting a condensable vapor from a supplied gas, comprising the steps of: i) condensing the condensable vapor by cooling the supplied gas at a condensing surface, such that the supplied gas is divided into at least one condensed fraction and a product gas; while ii) removing the at least one condensed fraction from the condensing surface by mechanical scraping means.

Abstract: Processes and systems are provided for converting a carbonaceous feedstock into a reaction gas and a syngas, involving a step of pyrolysing and methanating the feedstock in a pyrolysis chamber to produce the reaction gas and a step of gasifying unconverted feedstock in the presence of a reactant to produce a syngas.

Abstract: A process for extracting a condensable vapour from a supplied gas, comprising the steps of: i) condensing the condensable vapour by cooling the supplied gas at a condensing surface, such that the supplied gas is divided into at least one condensed fraction and a product gas; while ii) removing the at least one condensed fraction from the condensing surface by mechanical scraping means.

Abstract: Managing a networked storage system having a host operable to connect through a network fabric to storage apparatus comprises: a configuration component for inputting a configuration change into the networked storage system responsive to change instructions; a monitoring component operable in communication with the host and the network fabric to monitor I/O activity associated with elements of the networked storage system; an activity data storage component responsive to the monitoring component for storing a record of a monitored I/O activity; an analysis component, responsive to the configuration component for inputting configuration changes, for analyzing the record of a monitored I/O activity for a recent activity; and an alert component, responsive to the analysis component detecting a recent activity, for alerting the configuration component.

Abstract: Managing a networked storage system having a host operable to connect through a network fabric to storage apparatus comprises: a configuration component for inputting a configuration change into the networked storage system responsive to change instructions; a monitoring component operable in communication with the host and the network fabric to monitor I/O activity associated with elements of the networked storage system; an activity data storage component responsive to the monitoring component for storing a record of a monitored I/O activity; an analysis component, responsive to the configuration component for inputting configuration changes, for analysing the record of a monitored I/O activity for a recent activity; and an alert component, responsive to the analysis component detecting a recent activity, for alerting the configuration component.

Abstract: The invention relates to 3-(2?,2?-dimethylpropanoylamino)-tetrahydropyridin-2-one, and its pharmaceutical compositions and their use as a medicament intended to prevent or treat inflammatory disorders.

Abstract: Managing a networked storage system having a host operable to connect through a network fabric to storage apparatus comprises: a configuration component for inputting a configuration change into the networked storage system responsive to change instructions; a monitoring component operable in communication with the host and the network fabric to monitor I/O activity associated with elements of the networked storage system; an activity data storage component responsive to the monitoring component for storing a record of a monitored I/O activity; an analysis component, responsive to the configuration component for inputting configuration changes, for analysing the record of a monitored I/O activity for a recent activity; and an alert component, responsive to the analysis component detecting a recent activity, for alerting the configuration component.

Abstract: The invention relates to 3-(2?,2?-dimethylpropanoylamino)-tetrahydropyridin-2-one, and its pharmaceutical compositions and its use for preparing a medicament intended to prevent or treat inflammatory disorders.

Abstract: This invention is directed in part to methods, assays and/or kits for identifying an individual who has an autoimmune disease (such as rheumatoid arthritis), or who has an altered risk for having or developing the autoimmune disease. The methods in one aspect comprise determining the presence or absence of a nucleic acid variant within the somatostatin receptor type 2 (sstr2) gene in the individual's nucleic acids, wherein the presence of the nucleic acid variant is correlated with having the autoimmune disease or the altered risk. The nucleic acid variant may, for example, be a single nucleotide polymorphism (SNP).

Abstract: A light-emitting diode (LED) bulb for use with a leading-edge dimmer includes a shell and an LED contained within the shell. A base is attached to the bulb for connecting the LED bulb to an electrical socket. A driver circuit is configured to provide current to the LED. The driver circuit has an input filter circuit that includes a first inductor. In response to the input filter receiving a switched AC voltage from a leading-edge dimmer set to dim at 50%, the first inductor is configured to saturate. In response to an undimmed AC voltage from the leading-edge dimmer, the first inductor is configured to not saturate. The input filter also includes a bridge rectifier connected to the first inductor.

Abstract: Disclosed herein are methods of preventing or treating inflammatory diseases using sulfonamide analogs of 3-aminolactam compounds, each with aromatic “tail groups”. Compounds as defined by formulae (I) and (I?), and the medical uses of the compounds, are described herein.

Abstract: Disclosed herein are methods of preventing or treating inflammatory diseases using 3-aminolactam compounds, each with aromatic “tail groups”. Compounds as defined by formulae (I) and (I?), and the medical uses of the compounds, are described herein.

Abstract: The invention relates to the composition and use of a medicament comprising a fixed dose combination of droloxifene and clopidogrel.

Abstract: The invention relates to methods for the discovery of new chemical entities and pharmaceutical compositions with broad-spectrum chemokine inhibitor (BSCI) activity, together with the use of such agents as anti-inflammatory medicaments. In one aspect, there is provided a method for the identification of a compound or agent with BSCI activity comprising the steps of (a) firstly one or more candidate compounds or agents are screened for binding to a somatostatin receptor such as the type 2 somatostatin receptor (sstr2); then (b) compounds or agents which show binding to the somatostatin receptor are tested for BSCI activity in a functional assay.

Abstract: The invention concerns kits and methods for the diagnosis, prognosis and monitoring of cancer. In one aspect, there is provided a method for identifying whether or not a mammal is suffering from cancer, wherein the method comprises the steps of: (a) measuring a signal due to a non-IgG immunoglobulin binding to a carbohydrate-containing antigen in a sample from the mammal; and (b) comparing the signal measured in step (a) with a signal due to the non-IgG immunoglobulin binding to the carbohydrate-containing antigen in one or more samples from one or more mammals known to have cancer and/or with a signal due to the non-IgG immunoglobulin binding to the carbohydrate-containing antigen in one or more samples from one or more healthy mammals.