Patents by Inventor John Grant Aunins

John Grant Aunins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11266699
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: March 8, 2022
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • Patent number: 11185562
    Abstract: Compositions for methods of preventing or reducing pathogenic bacterial growth, proliferation, and/or colonization are described containing one or more types of non-pathogenic bacteria to be introduced into the gastrointestinal tract and effectively compete with pathogenic bacteria for monomeric or polymeric carbohydrate nutrients, and/or amino acid nutrients, and/or vitamin nutrients.
    Type: Grant
    Filed: February 4, 2014
    Date of Patent: November 30, 2021
    Assignee: Seres Therapeutics, Inc.
    Inventors: David N. Cook, Han Zhang, Anthony Mario D'Onofrio, David Arthur Berry, Mary-Jane Lombardo McKenzie, John Grant Aunins, Gregory McKenzie, Toshiro K. Ohsumi
  • Publication number: 20210252079
    Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
    Type: Application
    Filed: January 4, 2021
    Publication date: August 19, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Matthew R. HENN, David N. COOK, Toshiro K. OHSUMI, Mary-Jane Lombardo MCKENZIE, Kevin D. LITCOFSKY, Han ZHANG, John Grant AUNINS, David Arthur BERRY
  • Publication number: 20210244774
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: April 5, 2021
    Publication date: August 12, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Gregory MCKENZIE, Mary-Jane LOMBARDO MCKENZIE, David N. COOK, Marin VULIC, Geoffrey VON MALTZAHN, Brian GOODMAN, John Grant AUNINS, Matthew R. HENN, David Arthur BERRY, Jonathan WINKLER
  • Publication number: 20210169949
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 10, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
  • Publication number: 20210169947
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 10, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
  • Publication number: 20210169948
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 10, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
  • Publication number: 20210169946
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 14, 2020
    Publication date: June 10, 2021
    Applicant: Seres Therapeutics, Inc,
    Inventors: Matthew R. HENN, Geoffrey von MALTZAHN, Anthony Mario D'ONOFRIO, Kevin Daniel LITCOFSKY, David Arthur BERRY, David N. COOK, Noubar B. AFEYAN, John Grant AUNINS
  • Patent number: 10967011
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Grant
    Filed: August 3, 2018
    Date of Patent: April 6, 2021
    Assignee: Seres Therapeutics, Inc.
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Patent number: 10881696
    Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: January 5, 2021
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, David N. Cook, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Kevin D. Litcofsky, Han Zhang, John Grant Aunins, David Arthur Berry
  • Patent number: 10864235
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: December 15, 2020
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
  • Publication number: 20200345792
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 5, 2020
    Applicant: SERES THERAPEUTICS, INC.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • Patent number: 10590161
    Abstract: The current landscape for preparative chromatographic RNA purification uses reversed phase HPLC, but this technique presents many issues with process scale up and ion exchange for preparative purification has only been used for short RNAs. The invention provides preparative purification of RNA (e.g., mRNA) using ion (e.g., anion) exchange chromatography that allows for separation of longer RNAs up to 10,000 nucleotides in length via a scalable method. This method avoids problems with current techniques by using low pressure chromatography that is agreeable with existing equipment in cGMP commercial facilities, that uses aqueous-bases solutions as the mobile phase (rather than flammable of greater than 10 mg RNA/mL resin (e.g., using larger pore sorbents, >500 Angstroms, that display greater mRNA binding capacities), and that yields desired RNA salt forms for downstream formulation with no additional manipulation necessary (unlike ion pair reverse phase techniques).
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 17, 2020
    Assignee: ModernaTX, Inc.
    Inventors: William Joseph Issa, Joseph Louis Barberio, John Grant Aunins, Noubar B. Afeyan
  • Publication number: 20190350988
    Abstract: Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Application
    Filed: December 17, 2018
    Publication date: November 21, 2019
    Applicant: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Geoffrey von Maltzahn, Anthony Mario D'Onofrio, Kevin Daniel Litcofsky, David Arthur Berry, David N. Cook, Noubar B. Afeyan, John Grant Aunins
  • Patent number: 10258655
    Abstract: Provided are therapeutic compositions containing microbial populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: April 16, 2019
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, Kevin Daniel Litcofsky, Anthony Mario D'Onofrio, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Geoffrey von Maltzahn, David N. Cook, David Arthur Berry, Noubar B. Afeyan, John Grant Aunins
  • Publication number: 20190099455
    Abstract: Disclosed herein are therapeutic compositions containing non-pathogenic, germination-competent bacterial spores, for the prevention, control, and treatment of gastrointestinal diseases, disorders and conditions and for general nutritional health.
    Type: Application
    Filed: August 3, 2018
    Publication date: April 4, 2019
    Inventors: Gregory McKenzie, Mary-Jane Lombardo McKenzie, David N. Cook, Marin Vulic, Geoffrey von Maltzahn, Brian Goodman, John Grant Aunins, Matthew R. Henn, David Arthur Berry, Jonathan Winkler
  • Publication number: 20190085368
    Abstract: Described are methods for production of RNA transcripts using a non-amplified, linearized DNA tempate in an in vitro transcription reaction. Enzymatic 5? capping and oligo dT purification can also be included in the methods.
    Type: Application
    Filed: September 27, 2018
    Publication date: March 21, 2019
    Inventors: Stephane BANCEL, William Joseph ISSA, John Grant AUNINS, Tirtha CHAKRABORTY
  • Publication number: 20180353554
    Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
    Type: Application
    Filed: May 25, 2018
    Publication date: December 13, 2018
    Inventors: Matthew R. Henn, David N. Cook, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Kevin D. Litcofsky, Han Zhang, John Grant Aunins, David Arthur Berry
  • Patent number: 10138507
    Abstract: Described are methods for production of RNA transcripts using a non-amplified, linearized DNA template in an in vitro transcription reaction. Enzymatic 5? capping and oligo dT purification can also be included in the methods.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: November 27, 2018
    Assignee: ModernaTX, Inc.
    Inventors: Stephane Bancel, William Joseph Issa, John Grant Aunins, Tirtha Chakraborty
  • Patent number: 10076546
    Abstract: Provided are therapeutic compositions containing combinations of bacteria, for the maintenance or restoration of a healthy microbiota in the gastrointestinal tract of a mammalian subject, and methods for use thereof.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: September 18, 2018
    Assignee: Seres Therapeutics, Inc.
    Inventors: Matthew R. Henn, David N. Cook, Toshiro K. Ohsumi, Mary-Jane Lombardo McKenzie, Kevin D. Litcofsky, Han Zhang, John Grant Aunins, David Berry