Patents by Inventor John Griffiths
John Griffiths has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7915254Abstract: The present invention relates to a method of photodynamic therapy and to a method of inducing a photocytoxic effect which comprises applying to an area to be treated an effective amount of a compound of formula in which R1, R2, R3 and R4 each independently is an optionally -substituted linear, branched or cyclic hydrocarbon group, or R1 and R2 together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7- membered ring or R3 and R4 together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7- membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which —NR1R2 and —NR3R4 are the same and are selected from —N(CH3)2 or —N(CH2CH3)2; and exposing the area to light to activate the compound.Type: GrantFiled: April 4, 2008Date of Patent: March 29, 2011Assignee: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, David Ian Vernon
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Patent number: 7855197Abstract: A phenothiazinium compound of Formula (I) wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells.Type: GrantFiled: June 18, 2008Date of Patent: December 21, 2010Assignee: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, David Ian Vernon
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Patent number: 7732439Abstract: The present invention relates to a pharmaceutical composition which contains a compound of formula in which R1, R2, R3 and R4 are each n-butyl, where XP? is a counteranion and P is 1, 2 or 3, together with a pharmaceutically acceptable carrier, excipient or adjuvant.Type: GrantFiled: July 10, 2008Date of Patent: June 8, 2010Assignee: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, Richard George Tunstall, David John Howard Roberts, David Ian Vernon
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Patent number: 7666816Abstract: An aqueous suspension concentrate formulation of insoluble or partially soluble agrochemical active ingredient in which there is used a suspending system comprising silica and an alkypolyvinylpyrrolidone is disclosed.Type: GrantFiled: February 4, 2002Date of Patent: February 23, 2010Assignee: Syngenta LimitedInventors: Andrew John Griffiths, Sarah Elizabeth Barnett
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Publication number: 20090169747Abstract: Described are compositions and methods effective to improve the security obtainable for red phosphorescent inks printed, such as by ink jet printing. Specially designed polymeric chelating agents are water soluble and have a high chelating efficiency for lanthanide cations and are themselves strongly adsorbed on polymeric substrates, especially paper. The polymeric chelating agents comprise a polymer chain of either general formulae (1) or (2) containing pyridine-N-oxide, quinoline-N-oxide or isoquinoline-N oxide pendent ligand groups A, where m and n are independent integers in the range of from 1 to 10, and the number average molecular weight of the polymers lies in the range from 1×103 to 5×105: In one aspect a polymeric chelate as described is produced in situ in an aqueous ink formulation and is subsequently printed onto a substrate and dried.Type: ApplicationFiled: December 31, 2007Publication date: July 2, 2009Applicant: Pitney Bowes Inc.Inventors: Judith D. Auslander, John Griffiths, Penelope C. Myers
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Patent number: 7545148Abstract: In an electrochemical sensor, the potential difference applied to the electrochemical cell is raised to a measuring value at a rate determined to reduce the transient current. The maximum rate of change of the voltage is set to prevent saturation of an IE converter. The electrochemical cell may contain micro-electrodes as working and reference electrodes. The method may be applied to a battery powered, handheld device.Type: GrantFiled: August 3, 2005Date of Patent: June 9, 2009Assignee: Oxford Biosensors LimitedInventors: Kevin Lorimer, John Griffiths, Mark Hyland, Herbert Frank Askew, John Morton Broughall
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Publication number: 20080312219Abstract: The present invention relates to a phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells. The invention also relates to compositions comprising the compounds of Formula I, to selected compounds of Formula I, use of the compounds of Formula I as medicaments and as a PDT agent or a photodiagnostic agent, a conjugate or composite formed between a compound of Formula I and a polymer; and to a method for sterilising fluids in which the fluid is passed over the conjugate or composite whilst it is illuminated.Type: ApplicationFiled: May 12, 2008Publication date: December 18, 2008Applicant: PHOTOPHARMICA LIMITEDInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, Richard George Tunstall, David John Howard Roberts, David Ian Vernon
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Patent number: 7466678Abstract: A wireless device operating under the IEEE 802.11 specifications passively scans for a wireless access point coupled to a network backbone, wherein the scanning is performed using a default set of channels. The wireless device will then determine if the access point operates under an IEEE 802.11d specification, thus providing a country code to the wireless device. The wireless device will then utilize the country code to determine if the wireless device is legally authorized to communicate with the selected access point with wireless signal channels in addition to the default set of channels. The wireless device can then communicate with a selected access point utilizing any of the default set of channels and the wireless signal channels in addition to the default set of channels.Type: GrantFiled: December 29, 2003Date of Patent: December 16, 2008Assignee: Lenovo (Singapore) Pte. Ltd.Inventors: Daryl Carvis Cromer, Philip John Jakes, Howard Jeffrey Locker, Ronald John Griffiths, Jr.
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Patent number: 7467048Abstract: In an electrochemical sensor, a peak is detected by grouping data points in windows and detecting two or three windows between which the slope of the data changes sign. The peak can be more precisely detected by detecting the highest data point in the two or three windows.Type: GrantFiled: August 3, 2005Date of Patent: December 16, 2008Assignee: Oxford Biosensors LimitedInventors: Kevin Lorimer, John Griffiths, Mark Hyland
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Publication number: 20080275033Abstract: A phenothiazinium compound of Formula (I) wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells.Type: ApplicationFiled: June 18, 2008Publication date: November 6, 2008Applicant: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, Richard George Tunstall, David John Howard Roberts, David Ian Vernon
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Publication number: 20080268033Abstract: The present invention relates to a phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells. The invention also relates to compositions comprising the compounds of Formula I, to selected compounds of Formula I, use of the compounds of Formula I as medicaments and as a PDT agent or a photodiagnostic agent, a conjugate or composite formed between a compound of Formula I and a polymer; and to a method for sterilising fluids in which the fluid is passed over the conjugate or composite whilst it is illuminated.Type: ApplicationFiled: July 10, 2008Publication date: October 30, 2008Applicant: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, Richard George Tunstall, David John Howard Roberts, David Ian Vernon
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Publication number: 20080269060Abstract: An aqueous pre-mix suspension concentrate formulation comprising: (i) water, (ii) an HPPD inhibitor, in suspension in the water, and (iii) an electrolyte, in solution in the water which has improved stability of the HPPD inhibitor is disclosed.Type: ApplicationFiled: June 21, 2005Publication date: October 30, 2008Applicant: SYNGENTA CROP PROTECTION, INC.Inventors: Andrew John Griffiths, Rupert Heinrich Sohm, Carl Andrew Formstone
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Publication number: 20080261960Abstract: The present invention relates to a phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells. The invention also relates to compositions comprising the compounds of Formula I, to selected compounds of Formula I, use of the compounds of Formula I as medicaments and as a PDT agent or a photodiagnostic agent, a conjugate or composite formed between a compound of Formula I and a polymer; and to a method for sterilising fluids in which the fluid is passed over the conjugate or composite whilst it is illuminated.Type: ApplicationFiled: April 4, 2008Publication date: October 23, 2008Applicant: Photopharmica LimitedInventors: Stanley Beames Brown, Cassandra Claire O'Grady, John Griffiths, Kirste Joanne Mellish, Richard George Tunstall, David John Howard Roberts, David Ian Vernon
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Publication number: 20080223834Abstract: Embodiments of the present invention comprise an apparatus for laser marking individual objects with indicia at a marking station wherein a predetermined window exists during which each object can be marked as the objects are conveyed along at least one path at a predetermined speed, the apparatus comprising, at least first and second lasers positioned adjacent one or more paths configured to direct a laser beam onto the objects to mark the same with indicia as the objects pass through the marking station, with each of the first and second lasers marking alternate following objects as they pass through the marking station.Type: ApplicationFiled: March 16, 2007Publication date: September 18, 2008Inventors: Michael John Griffiths, Yancy Edward Fox
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Patent number: 7417153Abstract: A method for the production of acetals and ketals of 3-amino-5-(hydroxymethyl) cyclopenlane-1,2-diols of formula (I): (and/or the enantiomer), where R1 is H, C1-6-alkyl, C3-8-cycloalkyl or benzyl and (i) R2 is methyl and R3 is ethyl, (ii) R2 is H and R3 is C1-6-alkyl or phenyl or (iii) R2 and R3 together form a group of formula —(CH2)n— with n=4 to 6, present as free amines or as salts of di- or tri-basic organic acids, starting from 2-acetyl-2-aza-bicyclo[2.2.1]hept-5-en-3-one of formula (II): (and/or the enantiomer). The method is equally useful, depending on the starting material, for the production of enantiomerically-pure compounds, or mixtures with arbitrary enantiomeric content.Type: GrantFiled: January 24, 2005Date of Patent: August 26, 2008Assignee: Lonza AGInventors: Gareth-John Griffiths, Silvia Lange, Walter Brieden
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Patent number: 7407948Abstract: Phonoselenazinium compounds of Formula (1): and their use in photodynamic therapy (PDT), particularly as anti-infectives, as anti-cancer agents, and as sterilising agents both for direct use and in combination with a polymer, wherein: A and B are each independently selected from:Type: GrantFiled: March 20, 2007Date of Patent: August 5, 2008Assignee: Photopharmica LimitedInventors: John Griffiths, Stephen Anthony Gorman, Andrea Bell
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Patent number: 7405558Abstract: A method to determine deposits in a steam generator having the steps of creating a calibration standard having at least two rings of deposit material, subjecting the calibration standard to an eddy current signal, wherein an amplitude of the signal reflected from the calibration standard is used to obtain a polynomial equation fit of the reflected eddy current signals to actual thickness of the rings, obtaining a steam generator with tubes, initiating an eddy current signal into the tubes of the steam generator, detecting and recording reflections of the eddy current signal initiated into the tubes of the steam generator, and determining a thickness of the deposits in the steam generator from the recorded reflections of the eddy current signal and the polynomial equation.Type: GrantFiled: July 10, 2006Date of Patent: July 29, 2008Assignee: Areva NP, Inc.Inventors: Joseph R. Wyatt, John Griffith, Victor Newman, Jeffrey M. Fleck
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Patent number: 7371744Abstract: A phenothiazinium compound of Formula (I): wherein: A and B each independently is in which R? and R? each independently is a linear, branched or cyclic hydrocarbon group, or R? and R? together with the N atom to which they are attached form an optionally substituted 5-, 6- or 7-membered ring; and where XP? is a counteranion and P is 1, 2 or 3; except for the compounds in which A and B are both either —N(CH3)2 or —N(CH2CH3)2 for use in a treatment that requires removal, deactivation or killing of unwanted tissues or cells.Type: GrantFiled: November 26, 2003Date of Patent: May 13, 2008Assignee: Photopharmica LimitedInventors: Stanley B. Brown, Cassandra C. O'Grady, John Griffiths, Kirste J. Mellish, David I. Vernon
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Patent number: 7366304Abstract: A method that utilizes software and hardware mechanisms to meet the FCC requirement for a U-NII antenna to be an integral part of the device in which it operates, while providing wireless ready U-NII devices and CRUable U-NII radios. Enhancements are made to the software BIOS, including the inclusion of a table of approved radio-antenna PCI ID pairs to create an authentication scheme that verifies and authenticates the radio and antenna combination as being an FCC-approved unique coupling during boot-up of the system. The BIOS also comprises an OEM field that stores an encrypted secret key utilized to complete a second check of the radio model placed in the device. During boot up of the device, the PCI ID pairs from the BIOS are compared against the PCI ID of the radio and the secret key is checked against the radio model.Type: GrantFiled: October 7, 2003Date of Patent: April 29, 2008Assignee: Lenovo (Singapore) Pte. Ltd.Inventors: Daryl Carvis Cromer, Kazuo Fujii, Ronald John Griffiths, Jr., Masaharu Itoh, Philip John Jakes, Kozo Matsunaga, Masaki Oie
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Publication number: 20080007257Abstract: A method to determine deposits in a steam generator having the steps of creating a calibration standard having at least two rings of deposit material, subjecting the calibration standard to an eddy current signal, wherein an amplitude of the signal reflected from the calibration standard is used to obtain a polynomial equation fit of the reflected eddy current signals to actual thickness of the rings, obtaining a steam generator with tubes, initiating an eddy current signal into the tubes of the steam generator, detecting and recording reflections of the eddy current signal initiated into the tubes of the steam generator, and determining a thickness of the deposits in the steam generator from the recorded reflections of the eddy current signal and the polynomial equation.Type: ApplicationFiled: July 10, 2006Publication date: January 10, 2008Inventors: Joseph R. Wyatt, John Griffith, Victor Newman, Jeffrey M. Fleck