Patents by Inventor John Guastella

John Guastella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dipeptide apoptosis inhibitors and the use thereof
    Patent number: 6949516
    Abstract: The present invention is directed to novel dipeptides thereof, represented by the general Formula I: where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
    Type: Grant
    Filed: May 5, 2003
    Date of Patent: September 27, 2005
    Assignee: Cytovia, Inc.
    Inventors: John F. W. Keana, Sui Xiong Cai, John Guastella, Wu Yang, John A. Drewe, Eckard Weber
  • Dipeptide apoptosis inhibitors and the use thereof
    Publication number: 20050192231
    Abstract: The present invention is directed to novel dipeptides thereof, represented by the general Formula I: where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
    Type: Application
    Filed: April 7, 2005
    Publication date: September 1, 2005
    Inventors: John Keana, Sui Cai, John Guastella, Wu Yang, John Drewe, Eckard Weber
  • Dipeptide apoptosis inhibitors and the use thereof
    Publication number: 20030181391
    Abstract: The present invention is directed to novel dipeptides thereof, represented by the general Formula I: 1
    Type: Application
    Filed: May 5, 2003
    Publication date: September 25, 2003
    Applicant: Cytovia, Inc.
    Inventors: John F.W. Keana, Sui Xiong Cai, John Guastella, Wu Yang, John A. Drewe, Eckard Weber
  • Dipeptide apoptosis inhibitors and the thereof
    Patent number: 6596693
    Abstract: The present invention is directed to novel dipeptides thereof, represented by the general Formula I: where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
    Type: Grant
    Filed: August 31, 2000
    Date of Patent: July 22, 2003
    Assignee: Cytovia, Inc.
    Inventors: John F. W. Keana, Sui Xiong Cai, John Guastella, Wu Yang, John A. Drewe, Eckard Weber
  • Dipeptide apoptosis inhibitors and the use thereof
    Patent number: 6184210
    Abstract: The present invention is directed to novel dipeptides thereof, represented by the general Formula I: where R1-R3 and AA are defined herein. The present invention relates to the discovery that compounds having Formula I are potent inhibitors of apoptotic cell death. Therefore, the inhibitors of this invention can retard or block cell death in a variety of clinical conditions in which the loss of cells, tissues or entire organs occurs.
    Type: Grant
    Filed: March 16, 1999
    Date of Patent: February 6, 2001
    Assignee: Cytovia, Inc.
    Inventors: John F. W. Keana, Sui Xiong Cai, John Guastella, Wu Yang, John A. Drewe
  • Genes Coding for Bcl-y, a Bcl-2 Homologue
    Patent number: 5883229
    Abstract: Mammalian genes coding for bcl-y are disclosed. Bcl-y is involved in mediating cell death or survival.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 16, 1999
    Assignee: CoCensys, Inc.
    Inventor: John Guastella
  • Genes coding for bcl-y a bcl-2 homologue
    Patent number: 5789201
    Abstract: Mammalian genes coding for bcl-y are disclosed. Bcl-y is involved in mediating cell death or survival.
    Type: Grant
    Filed: February 11, 1997
    Date of Patent: August 4, 1998
    Assignee: CoCensys, Inc.
    Inventor: John Guastella