Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: A system and method for an exchange for auctioning senior life settlement policies are provided. The system and method may include a member creation system for approving new members, a policy approval and dematerialization system for approving and dematerializing a senior life settlement policy prior to being made available for auction, a policy listing system for selecting an approved and dematerialized senior life settlement policy for auction and for entering dynamic policy data to govern the auction for the selected senior life settlement policy, an auction system for accepting bids and determining whether an auction has been successful or whether an auction needs to be extended, and a trade confirmation system for confirming successful auctions and for tracking settlement of transactions which must occur within three business days of the date of auction.

Abstract: A carbon seal assembly includes a carbon seal element disposed about a central axis and that extends between a first end and a second end. The carbon seal element includes an inner step surface at an axial distance H1 with regard to the first end. An o-ring is adjacent to the inner step surface. The o-ring includes a cross-section diameter D2 such that a ratio H1/D2 is between 1.60-1.73.

Abstract: A coupling device including a drive member that is rotatable about an axis, a driven member that is substantially aligned with the drive member and is selectively rotatable about the axis, a speed sensing member that is coupled to the drive member and is movable between a first position and a second position in response to the rotational speed of the drive member, and a clutch member that is movable between a disengaged position and an engaged position in response to movement of the speed sensing member between the first position and the second position. At least a portion of the clutch member is removable without changing the alignment between the drive member and the driven member.

Abstract: A mobile power unit includes a mobile trailer and a plurality of support posts coupled to the mobile trailer, each support post having an axis. The mobile power unit further includes a plurality of solar panels, at least one of the plurality of solar panels being pivotally coupled to one of the plurality of support posts such that the at least one of the plurality of solar panels can be rotated about the axis of the support post to which it is attached.

Abstract: A coupling device including a drive member that is rotatable about an axis, a driven member that is substantially aligned with the drive member and is selectively rotatable about the axis, a speed sensing member that is coupled to the drive member and is movable between a first position and a second position in response to the rotational speed of the drive member, and a clutch member that is movable between a disengaged position and an engaged position in response to movement of the speed sensing member between the first position and the second position. At least a portion of the clutch member is removable without changing the alignment between the drive member and the driven member.

Abstract: A mobile surveillance and/or security unit. The unit includes a trailer, a tower mounted to the trailer, a plurality of apparatus positioned on the tower, and at least one power source configured to provide power to the plurality of apparatus. In addition, at least one of the plurality of apparatus is a communication apparatus.

Abstract: A valved connector for controlling the flow of fluid having a valve assembly positioned within a connector housing having a first position wherein the valve assembly prevents fluid flow through the connector housing, and a second position wherein the valve assembly permits fluid flow through the connector housing. The valve assembly may be movable from the first position to the second position by a male luer fitting. The valve assembly is configured for multiple and repeated access and also for minimizing fluid flow restrictions. The valved connector may be designed for use with a catheter to provide for “over the guidewire” placement or replacement techniques with little or no bleed-back or air embolism.

Abstract: An apparatus includes a container of pressurized fluid formulated to eliminate pests and a housing that is adapted to sit on a surface surrounding a pest dwelling with pest entrances, thereby forming a closed interior cavity and enclosing the pest entrances. The container has a spray release mechanism including a nozzle for releasing the pressurized fluid. The container sits on the surrounding surface within the closed interior cavity. The housing includes an activation mechanism and may include a first section housing including a first section opening edge associated with a first section flexible sealing member and a second section housing including a second section opening edge associated with a second section flexible sealing member. The first section opening edge and the second section opening edge define an upper surface opening in an upper surface of the housing.

Abstract: The subject invention provides a method for determining the most stable tertiary structure of a protein having a known primary structure which comprises the steps of (a) producing a reduced representation of the protein by assigning to the protein (i) all secondary structural motifs present therein and (ii) all .phi. and .PHI. dihedral angles for the amino acid residues present therein; (b) determining which conformations of the reduced representation are physically permissible, so as to determine which conformations of the protein are physically permissible; and (c) determining which of the physically permissible conformations of the protein possesses the lowest free energy, so as to thereby determine the most stable tertiary structure of the protein.