Abstract: The present invention is directed to antibodies and antigen binding fragments thereof having binding specificity for PACAP. The antibodies and antigen binding fragments thereof comprise the sequences of the VH, VL, and CDR polypeptides described herein, and the polynucleotides encoding them. Antibodies and antigen binding fragments described herein bind to and/or compete for binding to the same linear or conformational epitope(s) on human PACAP as an anti-PACAP antibody. The invention contemplates conjugates of anti-PACAP antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. Methods of making said anti-PACAP antibodies and antigen binding fragments thereof are also contemplated.

Abstract: A pressure energy storage device for the storage of kinetic energy of rotation in the form of potential energy of a compressed fluid and for converting the potential energy of the compressed fluid into kinetic energy of rotation. The pressure energy storage device includes a storage reservoir, a compressor driven by a rotating source to deliver pressurized fluid to the storage reservoir, and a primary fluid motor selectively operable to generate rotary motion by drawing off a portion of the pressurized fluid.