Patents by Inventor John H. Eldridge

John H. Eldridge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VAPORIZATION VESSEL AND METHOD
    Publication number: 20240084452
    Abstract: A tray for a vaporization vessel that includes a tray having a side wall, a bottom plate, one or more apertures that extend through the bottom plate, and a duct that extends through and from the bottom plate. The tray configured to support a solid reagent to be vaporized. A method of assembling the tray that includes forming a first tray that has the side wall and the bottom plate. A vaporization vessel that includes one or more of the trays.
    Type: Application
    Filed: October 13, 2023
    Publication date: March 14, 2024
    Inventors: Bryan C. HENDRIX, Scott L. Battle, David J. Eldridge, John N. Gregg, Jacob Thomas, Manuel F. Gonzales, Kenney R. Jordan, Benjamin H. Olson
  • Recombinant isfahan viral vectors
    Patent number: 9932564
    Abstract: Certain embodiments are directed to recombinant vesiculovirus encoding a heterologous polynucleotide and methods of using the same.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: April 3, 2018
    Assignees: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, PROFECTUS BIOSCIENCES, INC.
    Inventors: Demetrius Matassov, Rodion V. Gorchakov, Stefan Hamm, Rebecca Nowak, Robert L. Seymour, John H. Eldridge, Robert B. Tesh, David K. Clarke, Theresa E. Latham, Scott Weaver, Farooq Nasar
  • RECOMBINANT ISFAHAN VIRAL VECTORS
    Publication number: 20170067027
    Abstract: Certain embodiments are directed to recombinant vesiculovirus encoding a heterologous polynucleotide and methods of using the same.
    Type: Application
    Filed: February 27, 2015
    Publication date: March 9, 2017
    Inventors: Demetrius Matassov, Rodion V. Gorchakov, Stefan Hamm, Rebecca Nowak, Robert L. Seymour, John H. Eldridge, Robert B. Tesh, David K. Clarke, Theresa E. Latham, Scott Weaver
  • Immunogenic compositions for inducing an immune response to HIV
    Patent number: 8623382
    Abstract: The invention relates to immunogenic compositions for inducing an immune response to HIV comprising combinations of two, three, or four plasmids, where each plasmid is expressing a defined antigen, which may be a single antigen or a fusion of two or three antigens.
    Type: Grant
    Filed: January 18, 2011
    Date of Patent: January 7, 2014
    Assignee: Wyeth LLC
    Inventors: Maninder K. Sidhu, John H. Eldridge, Michael Egan, Zimra Israel
  • IMMUNOGENIC COMPOSITIONS FOR INDUCING AN IMMUNE RESPONSE TO HIV
    Publication number: 20120003265
    Abstract: The invention relates to immunogenic compositions for inducing an immune response to HIV comprising combinations of two, three, or four plasmids, where each plasmid is expressing a defined antigen, which may be a single antigen or a fusion of two or three antigens.
    Type: Application
    Filed: January 18, 2011
    Publication date: January 5, 2012
    Applicant: WYETH LLC
    Inventors: Maninder K. Sidhu, John H. Eldridge, Michael Egan, Zimra Israel
  • Mutant cholera holotoxin as an adjuvant
    Patent number: 7384640
    Abstract: A mutant cholera holotoxin featuring a point mutation at amino acid 29 of the A subunit, wherein the glutamic acid residue is replaced by an amino acid other than aspartic acid, is useful as an adjuvant in an antigenic composition to enhance the immune response in a vertebrate host to a selected antigen from a pathogenic bacterium, virus, fungus or parasite. In a particular embodiment, the amino acid 29 is histidine. The mutant cholera holotoxin may contain at least one additional mutation in the A subunit at a position other than amino acid 29. The antigenic composition may include a second adjuvant in addition to the mutant cholera holotoxin.
    Type: Grant
    Filed: September 30, 1999
    Date of Patent: June 10, 2008
    Assignees: Wyeth Holdings Corporation, The United States of America as represented by the Uniformed Services University of the Health Sciences
    Inventors: Randall K. Holmes, Michael G. Jobling, John H. Eldridge, Bruce A. Green, Gerald E. Hancock, Joel A. Peek
  • Meningococcal vaccines formulated with interleukin-12
    Patent number: 6841160
    Abstract: This invention pertains to vaccine compositions comprising a mixture of antigen, such as pneumococcal or meningococcal antigen, and interleukin IL-12, which may be adsorbed onto a mineral in suspension. The pneumococcal or meningococcal antigen may be conjugated to a carrier molecule. These vaccine compositions modulate the protective immune response to the antigen.
    Type: Grant
    Filed: November 4, 2003
    Date of Patent: January 11, 2005
    Assignee: Wyeth Holdings Corporation
    Inventors: Vincent J. LaPosta, John H. Eldridge
  • Pneumococcal and meningococcal vaccines formulated with interleukin-12
    Publication number: 20040105866
    Abstract: This invention pertains to vaccine compositions comprising a mixture of antigen, such as pneumococcal or meningococcal antigen, and interleukin IL-12, which may be adsorbed onto a mineral in suspension. The pneumococcal or meningococcal antigen may be conjugated to a carrier molecule. These vaccine compositions modulate the protective immune response to the antigen.
    Type: Application
    Filed: November 4, 2003
    Publication date: June 3, 2004
    Inventors: Vincent J. LaPosta, John H. Eldridge
  • Pneumococcal vaccines formulated with interleukin-12
    Patent number: 6709658
    Abstract: This invention pertains to vaccine compositions comprising a mixture of antigen, such as a pneumococcal or meningococcal antigen, and interleukin IL-12, which may be adsorbed onto a mineral in suspension. The pneumococcal or meningococcal antigen may be conjugated to a carrier molecule. These vaccine compositions modulate the protective immune response to the antigen.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: March 23, 2004
    Assignee: Wyeth Holdings Corporation
    Inventors: Vincent J. LaPosta, John H. Eldridge
  • Immunogenic composition of interleukin-12 (IL-12), alum, herpes simplex viral (HSV) antigen, and method thereof
    Patent number: 6488936
    Abstract: This invention pertains to vaccine compositions comprising a mixture of antigen, such as a herpes simplex virus antigen, and the interleukin IL-12, which may be adsorbed onto a mineral in suspension. These vaccine compositions modulate the protective immune response to the antigen.
    Type: Grant
    Filed: February 10, 1999
    Date of Patent: December 3, 2002
    Assignee: Wyeth
    Inventors: Eric M. Mishkin, John H. Eldridge
  • Composition for delivering bioactive agents for immune response and its preparation
    Patent number: 6024983
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: February 15, 2000
    Assignees: Southern Research Institute, The Uab Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their release
    Patent number: 5942252
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 24, 1999
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissue and controlling their release
    Patent number: 5853763
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 29, 1998
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method for delivering bioactive agents into and through the mucosally-associated lymphoid tissues and controlling their release
    Patent number: 5820883
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a. biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 13, 1998
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method for delivering bioactive agents into and through the mucosally associated lymphoid tissues and controlling their release
    Patent number: 5814344
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 29, 1998
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
    Patent number: 5811128
    Abstract: A method, and compositions for use therein capable, of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size less than approximately ten micrometers and administering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immunity.
    Type: Grant
    Filed: September 7, 1993
    Date of Patent: September 22, 1998
    Assignees: Southern Research Institute, The UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas
  • Method of potentiating an immune response
    Patent number: 5075109
    Abstract: A method of delivering a bioactive agent to an animal entailing the steps of encapsulating effective amounts of the agent in a biocompatible excipient to form microcapsules having a size ranging from between approximately one micrometer to approximately ten micrometers and admnistering effective amounts of the microcapsules to the animal. A pulsatile response is obtained, as well as mucosal and systemic immuity. Related compositions are also provided.
    Type: Grant
    Filed: March 18, 1988
    Date of Patent: December 24, 1991
    Assignees: Southern Research Institute, UAB Research Foundation
    Inventors: Thomas R. Tice, Richard M. Gilley, John H. Eldridge, Jay K. Staas, Melinda G. Hollingshead, William M. Shannon