Abstract: A peer-to-peer conversation captioning (“PPCC”) system includes a first electronic device for a first user, a second electronic device for a second user, and a PPCC server. The PPCC system further includes a virtual relay entity, which includes a first virtual router for the first language, a second virtual router for the second language, and a global switch. The virtual routers include a speech-to-text engine, a translation engine, a text-to-speech engine, and a multiplexer. The speech-to-text engine converts a user's spoken language to texts and sends the texts to the global switch. Then, the translation engine receives and translates the texts where the text-to-speech engine converts the translated texts to voice. The multiplexer combines the translated texts and the voice to be sent to another user.

Abstract: HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.

Abstract: Audio media items with dynamic content are synchronized with a transcript by automatically generating, for a first version of an audio media item, a transcript, and an audio fingerprint indicative of audio characteristics of each of a set of segments of the first version of the audio media item. A playback device receives the transcript and the first audio fingerprint to a playback device and presents the transcript during playback of a second version of the audio media item in accordance with a comparison of the audio fingerprint and a second audio fingerprint for the second version of the audio media item.

Abstract: Provided are genetically modified NK cells expressing a chimeric antigen receptor targeting an EGFR superfamily receptor. The CAR can comprise an intracellular domain of Fc?RI? and further recombinant proteins expressed by the genetically modified NK cells are CD16, autocrine growth stimulating cytokines, and optionally one of IL-12, a TGF-beta trap, or a homing receptor. Also described are methods for treating a patient having or suspected of having a disease that is treatable with NK-92 cells, such as cancer, comprising administering to the patient the genetically modified NK cells.

Abstract: Provided are genetically modified NK cells expressing a chimeric antigen receptor targeting an EGFR superfamily receptor. The CAR can comprise an intracellular domain of Fc?RI? and further recombinant proteins expressed by the genetically modified NK cells are CD16, autocrine growth stimulating cytokines, and optionally one of IL-12, a TGF-beta trap, or a homing receptor. Also described are methods for treating a patient having or suspected of having a disease that is treatable with NK-92 cells, such as cancer, comprising administering to the patient the genetically modified NK cells.

Abstract: A captioned telephone service (CTS) system provides a CTS system which includes a CTS server, a user device, and a user application where the CTS system provides a call resumption alert module to the user such that the call resumption alert module sends an alert to the user to assist the user in re-engaging with the phone call when the call has resumed from the peer device after being on hold. The call resumption alert module provides a timer mode, any text mode, and specific text mode, of which the user can select one or more modes. Alternatively, the call resumption alert module may include a call resumption checking module and an alert module. The call resumption checking module checks whether the phone call resumed from the peer device, and the alert module generates an alert upon receiving a call resumption message from the call resumption checking module.

Abstract: A container mixer is provided that includes a single container moveable between a vertical position and a horizontal position. A mixing apparatus includes at least one blade disposed on a shaft that is rotatably driven by a motor. A frame is configured to support the container and facilitate movement of the container from the vertical position to the horizontal position. A container mixer is also provided that includes a single container having a first end, at least one side wall extending from the first end, and a second end. A mixing apparatus is moveable relative to the container between a vertical position where the shaft is inserted through the second end of the container and a horizontal position wherein the shaft is inserted through the through hole in the side wall of the container. A method of preparing an emulsion product therewith is also provided.

Abstract: A method performed by a data storage apparatus of maintaining filesystem object attributes in connection with a plurality of drivers is provided. Each driver of the plurality is configured to operate on a respective set of filesystem objects. The method includes (a) for each driver of the plurality, creating a respective driver-specific storage volume; (b) storing, within each driver-specific storage volume, attributes specific to respective filesystem objects operated on by the driver of that driver-specific storage volume; and (c) while operating a particular driver of the plurality on a particular filesystem object, using values of the stored attributes specific to that particular filesystem object operated on by that particular driver. An apparatus, system, and computer program product for performing a similar method are also provided.

Abstract: A recombinant natural killer (NK) cell or T-cell composition is transfected with a nucleic acid encoding i) a homing receptor; ii) an antigen binding protein (ABP) or a chimeric antigen receptor (CAR) that specifically binds a target antigen; iii) an Fc Receptor; and/or iv) a secreted immune modulator selected from a TGF? inhibitor and/or IL-12, where the recombinant cell is gamma (?)-irradiated conferring inhibition of cell proliferation with transient activity of the transfected molecules including the secreted immune modulators for up to 72 hours.

Abstract: A recombinant natural killer (NK) cell or T-cell composition is transfected with a nucleic acid encoding i) a homing receptor; ii) an antigen binding protein (ABP) or a chimeric antigen receptor (CAR) that specifically binds a target antigen; iii) an Fc Receptor; and/or iv) a secreted immune modulator selected from a TGF? inhibitor and/or IL-12, where the recombinant cell is gamma (?)-irradiated conferring inhibition of cell proliferation with transient activity of the transfected molecules including the secreted immune modulators for up to 72 hours.

Abstract: A system for centralized captioned telephone service (“C-CTS”), which includes a C-CTS system (“C-CTSS”) for providing a transcription service to a user subscribed to the C-CTS during a phone call with a peer; a mobile communications device of the user which includes a first phone number assigned from a carrier of the user; a communications device of the peer which includes a second phone number; and a plurality of caption providers that communicate with the C-CTSS. The first phone number is associated with the C-CTSS and each of the caption providers provides a captioned telephone service. A carrier of the first phone number includes a voice network, a data network, and a database that stores the first phone number of the user which is subscribed to the C-CTS. The C-CTSS includes a database that stores the first phone number of the user.

Abstract: HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.

Abstract: HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.

Abstract: A captioned telephone service system having the text-to-speech and answer assistance functions includes a captioner, a text-to-speech system, and an answer assistance system. The captioner provides captions to a user during a phone call between the user and a peer by receiving the peer’s voice from a peer device, transcribing the peer’s voice into caption data, and transferring the caption data to the user device. The text-to-speech system is configured to receive text data from the user device, convert the text data into speech, and transfer the voice of the speech to the peer device via the voice path in real time. The answer assistance system is configured to receive the caption data from the captioner, analyze the caption data to identify a question, analyze the question to generate answer suggestions, and forward the answer suggestions to the user device for review, editing, and selection.

Abstract: A system for identifying spoken language in a telecommunications relay service, which includes a call serving entity; and a plurality of automatic speech recognition groups where each of the automatic speech recognition groups includes an associated automatic speech recognition engine that recognizes and transcribes speech to a predefined language. One of the plurality of automatic speech recognition groups is set as a default automatic speech recognition group and automatic speech recognition engines transcribe and convert peer voices into text packets. The text packets are scored by the automatic speech recognition engine and transmitted to the call serving entity to determine whether the text packets meet a predetermined threshold based on their respective scores with the text packet having the highest score that meets or exceeds the predetermine threshold transmitted to a user.

Abstract: The present disclosure provides methods for treating or preventing Huntington's disease (HD) in a subject in need thereof, comprising administering a therapeutic agent that activates mTORC 1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment, and methods for modulating mHTT-associated metabolic phenotypes and/or reversal of striatal atrophy by administering a therapeutic agent that activates mTORC1 function and/or increases Ras Homolog Enriched in Striatum (Rhes) level in the subject's brain as compared to the function or level in the subject prior to treatment.

Abstract: A method performed by a data storage apparatus of maintaining filesystem object attributes in connection with a plurality of drivers is provided. Each driver of the plurality is configured to operate on a respective set of filesystem objects. The method includes (a) for each driver of the plurality, creating a respective driver-specific storage volume; (b) storing, within each driver-specific storage volume, attributes specific to respective filesystem objects operated on by the driver of that driver-specific storage volume; and (c) while operating a particular driver of the plurality on a particular filesystem object, using values of the stored attributes specific to that particular filesystem object operated on by that particular driver. An apparatus, system, and computer program product for performing a similar method are also provided.

Abstract: A system for centralized captioned telephone service (“C-CTS”), which includes a C-CTS system (“C-CTSS”) for providing a transcription service to a user subscribed to the C-CTS during a phone call with a peer; a mobile communications device of the user which includes a first phone number assigned from a carrier of the user; a communications device of the peer which includes a second phone number; and a plurality of caption providers that communicate with the C-CTSS. The first phone number is associated with the C-CTSS and each of the caption providers provides a captioned telephone service. A carrier of the first phone number includes a voice network, a data network, and a database that stores the first phone number of the user which is subscribed to the C-CTS. The C-CTSS includes a database that stores the first phone number of the user.

Abstract: A system for identifying spoken language in a telecommunications relay service, which includes a call serving entity; and a plurality of automatic speech recognition groups where each of the automatic speech recognition groups includes an associated automatic speech recognition engine that recognizes and transcribes speech to a predefined language. One of the plurality of automatic speech recognition groups is set as a default automatic speech recognition group and automatic speech recognition engines transcribe and convert peer voices into text packets. The text packets are scored by the automatic speech recognition engine and transmitted to the call serving entity to determine whether the text packets meet a predetermined threshold based on their respective scores with the text packet having the highest score that meets or exceeds the predetermine threshold transmitted to a user.

Abstract: HIV treatment, and especially treatment of latent infected CD4 cells, can be significantly improved using a kick-and-kill approach that employs an immune stimulation component and/or HDAC inhibition as one treatment component, and that may also include a second component in which a vaccine composition, various NK cells, CAR-T cells, and/or broadly neutralizing antibodies are administered.