Patents by Inventor John H. Paul, III

John H. Paul, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Control of harmful algal blooms by induction of programmed cell death
    Patent number: 8476196
    Abstract: The subject invention pertains to compositions, apparatus, and methods for controlling harmful algae and harmful algal bloom (HAB) based on the induction of the programmed cell death (PCD; apoptosis) pathway in the harmful algae, and to kits for determining algal susceptibility to PCD induction.
    Type: Grant
    Filed: July 6, 2010
    Date of Patent: July 2, 2013
    Assignee: University of South Florida
    Inventors: John H. Paul, III, David John
  • Detection of polyketide synthetase gene expression in
    Patent number: 7888031
    Abstract: The present invention concerns an assay for the detection of polyketide synthetase (PKS) mRNA from the red tide dinoflagellate Karenia brevis. Another aspect of the invention concerns NASBA primers and a molecular beacon that enable detection of mRNA of one of the PKS genes. In another aspect, the present invention includes an internal control RNA (IC-RNA) that enables quantitative detection of the target as well as correction for inhibition of amplification. The assay of the invention provides a rapid and specific detection of the putative toxin-producing genes of the Florida Red Tide Organism. The assay of the invention is useful for determining the virulence of red tide blooms.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: February 15, 2011
    Assignee: University of South Florida
    Inventor: John H. Paul, III
  • CONTROL OF HARMFUL ALGAL BLOOMS BY INDUCTION OF PROGRAMMED CELL DEATH
    Publication number: 20110021357
    Abstract: The subject invention pertains to compositions, apparatus, and methods for controlling harmful algae and harmful algal bloom (HAB) based on the induction of the programmed cell death (PCD; apoptosis) pathway in the harmful algae, and to kits for determining algal susceptibility to PCD induction.
    Type: Application
    Filed: July 6, 2010
    Publication date: January 27, 2011
    Applicant: UNIVERSITY OF SOUTH FLORIDA
    Inventors: JOHN H. PAUL, III, David John
  • Materials and methods for detection of enterovirus and norovirus
    Patent number: 7563577
    Abstract: The invention provides polynucleotides and methods for detecting and quantifying RNA viruses, such as enteroviruses and noroviruses. In one aspect, the invention provides amplification primers and labeled molecular beacons for amplification of viral nucleic acid sequences. In another aspect, the invention provides a synthetic RNA internal control. In another aspect, the invention provides a kit for detecting the presence of enterovirus and/or norovirus in a sample.
    Type: Grant
    Filed: March 2, 2007
    Date of Patent: July 21, 2009
    Assignee: University of South Florida
    Inventors: John H. Paul, III, Erica T. Casper, Stacey S. Patterson
  • Detection of Polyketide Synthetase Gene Expression in Karenia Brevis
    Publication number: 20090075286
    Abstract: The present invention concerns an assay for the detection of polyketide synthetase (PKS) mRNA from the red tide dinoflagellate Karenia brevis. Another aspect of the invention concerns NASBA primers and a molecular beacon that enable detection of mRNA of one of the PKS genes. In another aspect, the present invention includes an internal control RNA (IC-RNA) that enables quantitative detection of the target as well as correction for inhibition of amplification. The assay of the invention provides a rapid and specific detection of the putative toxin-producing genes of the Florida Red Tide Organism. The assay of the invention is useful for determining the virulence of red tide blooms.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 19, 2009
    Inventor: John H. Paul III
  • Detection of polyketide synthetase gene expression in
    Patent number: 7422857
    Abstract: The present invention concerns an assay for the detection of polyketide synthetase (PKS) mRNA from the red tide dinoflagellate Karenia brevis. Another aspect of the invention concerns NASBA primers and a molecular beacon that enable detection of mRNA of one of the PKS genes. In another aspect, the present invention includes an internal control RNA (IC-RNA) that enables quantitative detection of the target as well as correction for inhibition of amplification. The assay of the invention provides a rapid and specific detection of the putative toxin-producing genes of the Florida Red Tide Organism. The assay of the invention is useful for determining the virulence of red tide blooms.
    Type: Grant
    Filed: October 30, 2006
    Date of Patent: September 9, 2008
    Assignee: University of South Florida
    Inventor: John H. Paul, III
  • Materials and methods for detection of enterovirus and norovirus
    Patent number: 7205112
    Abstract: The invention provides polynucleotides and methods for detecting and quantifying RNA viruses, such as enteroviruses and noroviruses. In one aspect, the invention provides amplification primers and labeled molecular beacons for amplification of viral nucleic acid sequences. In another aspect, the invention provides a synthetic RNA internal control. In another aspect, the invention provides a kit for detecting the presence of enterovirus and/or norovirus in a sample.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: April 17, 2007
    Assignee: University of South Florida
    Inventors: John H. Paul, III, Erica T. Casper, Stacey S. Patterson