Abstract: The present invention provides systems, methods, and devices for electroporation-based therapies (EBTs). Embodiments provide patient-specific treatment protocols derived by the numerical modeling of 3D reconstructions of target tissue from images taken of the tissue, and optionally accounting for one or more of physical constraints or dynamic tissue properties. The present invention further relates to systems, methods, and devices for delivering bipolar electric pulses for irreversible electroporation exhibiting reduced or no damage to tissue typically associated with an EBT-induced excessive charge delivered to the tissue.

Abstract: A tire removal tool including a base frame, an elongated lever arm spaced from the base frame, and articulated fulcrum post structure pivotally supporting the lever arm on the base frame and a tire bead engaging plate carried on one end of the fulcrum arm. A hydraulic jack is pivotally supported on the base frame beneath the opposite end of the lever arm from that which carries the bead engaging plate, and is mounted for transverse sliding movement on the base frame in a direction normal to the longitudinal axis of the lever arm. A tire positioning slide assembly is slidably mounted on the base frame for sliding movement in a direction extending parallel to the longitudinal axis of the lever arm.