Abstract: Quinone Compounds and Their Uses for the Treatment of Cancer Quinone compounds having useful therapeutic activity such as anticancer activity, and compositions comprising such compounds, are described. The use of such compounds and compositions in the treatment of cancer is also described.

Abstract: Combretastatins and their use in treating conditions characterised by abnormal vasculature or cancer by irradiation of the combretastatin in situ, and kits comprising such compounds.

Abstract: Quinone Compounds and Their Uses for the Treatment of Cancer Quinone compounds having useful therapeutic activity such as anticancer activity, and compositions comprising such compounds, are described. The use of such compounds and compositions in the treatment of cancer is also described.

Abstract: A technique is provided or integrating system design, sales, and manufacturing functions. Systems including networked and programmable electrical components, such as motor control centers, and other electrical power control arrangements are designed, and a database is created for the design, including component and system designation data. The database may further include configuration information, settings, and so forth. The database is used as a tool in establishing a sales solicitation proposal from which sales of the system are offered. The same database is then used to program the various components of the system, such as through a temporary network link or via a permanent data network once the system is assembled.

Abstract: The present invention relates to stilbene and quinine compounds related to combretastatin A-4 and their use as anticancer compounds and prodrugs. The compounds include those with an alkyl group on the double bond of cis or trans-stilbenes, compounds with one or more (and preferably 2 or 3) alkyl group substituents on the stilbene a ring, compounds with an alkoxy group other than methoxy at position 3, 4 and/or 5 of the stilbene A ring, compounds (or prodrugs) in which BOC amino acid esters are formed with the phenolic hydroxyl at the 3-position of the B ring and compounds (or prodrugs) based on a benzoquinone B ring. The present invention further relates to the photochemical reactions of stilbene compounds, either the above compounds disclosed for the first time herein or compounds based on prior art stilbenes.

Abstract: Compounds are disclosed that are designed to mimic the activity of combretastatin A-4 based on chalcone, aurone, or indanone structures, or involving benzoquinone or quinone rings. The anti-cancer activity of exemplified compounds is demonstrated in a range of in vitro and in vivo assays.