Patents by Inventor John Hamberger

John Hamberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HERPESVIRUS COMPOSITIONS AND RELATED METHODS
    Publication number: 20260007739
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable exetpients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compostions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Application
    Filed: January 3, 2025
    Publication date: January 8, 2026
    Inventors: Stephen ANDERSON, Simon DELAGRAVE, John HAMBERGER, Qinglian LI, Sophia MUNDLE, Nausheen RAHMAN
  • Herpesvirus compositions and related methods
    Patent number: 12214035
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compostions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Grant
    Filed: January 14, 2022
    Date of Patent: February 4, 2025
    Assignees: SANOFI PASTEUR LIMITED, SANOFI PASTEUR INC.
    Inventors: Stephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
  • HERPESVIRUS COMPOSITIONS AND RELATED METHODS
    Publication number: 20220133881
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compostions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Application
    Filed: January 14, 2022
    Publication date: May 5, 2022
    Inventors: Stephen ANDERSON, Simon DELAGRAVE, John HAMBERGER, Qinglian LI, Sophia MUNDLE, Nausheen RAHMAN
  • Herpesvirus compositions and related methods
    Patent number: 11260123
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable exctpients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: March 1, 2022
    Assignees: SANOFI PASTEUR LIMITED, SANOFI PASTEUR BIOLOGICS, LLC
    Inventors: Stephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
  • HERPESVIRUS COMPOSITIONS AND RELATED METHODS
    Publication number: 20150150964
    Abstract: The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization.
    Type: Application
    Filed: May 21, 2013
    Publication date: June 4, 2015
    Inventors: Stephen Anderson, Simon Delagrave, John Hamberger, Qinglian Li, Sophia Mundle, Nausheen Rahman
  • Compositions and methods for the production of alpha-herpesviruses
    Patent number: 8877492
    Abstract: The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: November 4, 2014
    Assignee: Sanofi Pasteur Biologics, LLC
    Inventors: Simon Delagrave, Rachid Oubelaid, John Hamberger
  • Compositions and Methods for the Production of Alpha-Herpesviruses
    Publication number: 20110201087
    Abstract: The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media.
    Type: Application
    Filed: August 11, 2009
    Publication date: August 18, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Simon Delagrave, Rachid Oubelaid, John Hamberger
  • Compositions and methods for the production of alpha-herpesviruses
    Patent number: RE47768
    Abstract: The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 17, 2019
    Assignee: Sanofi Pasteur Biologics LLC
    Inventors: Simon Delagrave, Rachid Oubelaid, John Hamberger