Patents by Inventor John Hardham

John Hardham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VMP-like sequences of pathogenic Borrelia
    Publication number: 20070117970
    Abstract: The present invention relates to DNA sequences encoding Vmp-like polypeptides of pathogenic Borrelia, the use of the DNA sequences in recombinant vectors to express polypeptides, the encoded amino acid sequences, application of the DNA and amino acid sequences to the production of polypeptides as antigens for immunoprophylaxis, immunotherapy, and immunodiagnosis. Also disclosed are the use of the nucleic acid sequences as probes or primers for the detection of organisms causing Lyme disease, relapsing fever, or related disorders, and kits designed to facilitate methods of using the described polypeptides, DNA segments and antibodies.
    Type: Application
    Filed: August 7, 2006
    Publication date: May 24, 2007
    Inventors: Steven Norris, Jing-Ren Zhang, John Hardham, Jerrilyn Howell, Alan Barbour, George Weinstock
  • Vaccine for periodontal disease
    Publication number: 20060257429
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, and vaccines comprising such bacteria. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease.
    Type: Application
    Filed: October 11, 2004
    Publication date: November 16, 2006
    Inventors: Kimberly Dreier, John Hardham, Rajendra Krishnan, David McGavin
  • Vaccine for periodontal disease
    Publication number: 20050010032
    Abstract: The present invention relates to novel bacterial isolates identified by their 16S rRNA DNA, that cause periodontal disease in companion animals, polynucleotide sequences contained therein, polypeptides encoded by such polynucleotide sequences and vaccines comprising such bacteria, polynucleotides, or polypeptides. Also provided are methods for treating and preventing periodontal disease and kits for detecting and treating periodontal disease kits for detecting and preventing periodontal disease. In addition, methods for assessing the efficacy of a vaccine against periodontal diseases in an animal are provided.
    Type: Application
    Filed: May 21, 2004
    Publication date: January 13, 2005
    Inventors: John Hardham, Kendall King, Rajendra Krishnan, Kimberly Dreier, David McGavin, John Haworth