Abstract: Herein described is a syringe assembly configured for the in situ lyophilization of an initial liquid preparation into a lyophilized product as well as the subsequent sealing of the lyophilized product for storage and transport, user reconstitution of the lyophilized product, and dispensing of the lyophilized product in rehydrated form to a patient in a medical setting, all in the same syringe. The combination lyophilization and dispensing syringe assemblies of the present invention greatly enhance the efficiency of the lyophilization process and find particular utility in conjunction with the dedicated lyophilization apparatus and methods described in U.S. Pat. Nos. 11,536,512 and 11,723,870. In particularly preferred embodiments, the present invention provides for shortened lyophilization cycles in a syringe barrel optionally fitted with a sealing Luer lock cap at its distal end and a vented stopper at its proximal end. During lyophilization, gas may flow out of the syringe barrel and through the stopper.

Abstract: Herein described are an assembly, apparatus, and method for lyophilization that utilizes a thermal block made from a conductive material, the block having multiple wells designed and dimensioned to receive containers carrying material to be lyophilized in situ. In preferred embodiments, a vented silicone pad covers the wells and secures the containers therein, and a similarly vented rigid plate in turn secures the silicone pad by fastening it to the thermal block. The assembly can be turned up to 90 degrees resulting in the turning of the containers from an upright position to a horizontal position, a position in which the distance through which sublimation must progress is drastically reduced so as to greatly enhance the efficiency of the lyophilization process.

Abstract: Herein described are an assembly, apparatus, and method for lyophilization that utilizes a thermal block made from a conductive material, the block having multiple wells designed and dimensioned to receive containers carrying material to be lyophilized in situ. In preferred embodiments, a vented silicone pad covers the wells and secures the containers therein, and a similarly vented rigid plate in turn secures the silicone pad by fastening it to the thermal block. The assembly can be turned up to 90 degrees resulting in the turning of the containers from an upright position to a horizontal position, a position in which the distance through which sublimation must progress is drastically reduced so as to greatly enhance the efficiency of the lyophilization process.

Abstract: Herein described are an assembly, apparatus and method for lyophilization that utilizes a thermal block made from a conductive material, the block having multiple wells designed and dimensioned to receive containers carrying material to be lyophilized in situ. In preferred embodiments, a vented silicone pad covers the wells and secures the containers therein, and a similarly vented rigid plate in turn secures the silicone pad by fastening it to the thermal block. The assembly can be turned up to 90 degrees resulting in the turning of the containers from an upright position to a horizontal position, a position in which the distance through which sublimation must progress is drastically reduced so as to greatly enhance the efficiency of the lyophilization process.

Abstract: Herein described are an assembly, apparatus and method for lyophilization that utilizes a thermal block made from a conductive material, the block having multiple wells designed and dimensioned to receive containers carrying material to be lyophilized in situ. In preferred embodiments, a vented silicone pad covers the wells and secures the containers therein, and a similarly vented rigid plate in turn secures the silicone pad by fastening it to the thermal block. The assembly can be turned up to 90 degrees resulting in the turning of the containers from an upright position to a horizontal position, a position in which the distance through which sublimation must progress is drastically reduced so as to greatly enhance the efficiency of the lyophilization process.

Abstract: An apparatus and method for lyophilization, the apparatus includes a block made from a conductive material. The block has multiple wells dimensioned to receive containers wherein the depth of the wells is proportional to the length of the containers. A silicone pad covers the well and can secure the containers in the well. A metal plate can secure the silicone pad by fastening it to the block. The silicone plate and the metal plate can have vents to allow vapors from the containers to escape. The apparatus can be turned up to 90 degrees resulting in the turning of the containers from an upright position to a horizontal position. The container can be a syringe.

Abstract: A treatment for male erectile dysfunction comprising separately storing a lyophilized composition of vasoactive agents and a carrier gel, mixing said lyophilized composition of vasoactive agents and said carrier gel creating a homogeneous mixture and applying said homogeneous mixture to the meatus of the glans penis. A system for the treatment of male erectile dysfunction comprising a syringe coupling system for the storage, mixing and application of therapeutic compounds for the treatment of erectile dysfunction, said system further comprising a first syringe and a second syringe. The first and second syringes are filled with a lyophilized composition of vasoactive agents or a carrier gel. The system includes a locking device coupling said syringes to facilitate the transfer of said lyophilized composition of vasoactive agents and carrier gel between the syringes and a penile adapter for applying the therapeutic compounds for the treatment of erectile dysfunction to the meatus of the glans penis.

Abstract: A barrier system constructed of modules which includes a frame, a concrete foundation, a frame attached to the concrete foundation and supporting a non-vertical front side plate and a vertical rear side plate so that the front side plate and rear side plate meet at the top and are spread apart from each other at the bottom, slotted connectors on the front side and connectors on the rear side, the module adapted to be joined to an adjacent module either at the same elevation or a different elevation. The modules are joined together via bolts in the rear side connectors and threaded toggle bolts and drop toggle nuts through the front side slotted connectors. Extenders within the slots of the open ended connectors are used when connecting adjacent modules at different elevations to accommodate for slotted connectors of different sizes which must be connected to each other.

Abstract: A treatment for male erectile dysfunction comprising separately storing a lyophilized composition of vasoactive agents and a carrier gel, mixing said lyophilized composition of vasoactive agents and said carrier gel creating a homogeneous mixture and applying said homogeneous mixture to the meatus of the glans penis. A system for the treatment of male erectile dysfunction comprising a syringe coupling system for the storage, mixing and application of therapeutic compounds for the treatment of erectile dysfunction, said system further comprising a first syringe and a second syringe. The first and second syringes are filled with a lyophilized composition of vasoactive agents or a carrier gel. The system includes a locking device coupling said syringes to facilitate the transfer of said lyophilized composition of vasoactive agents and carrier gel between the syringes and a penile adapter for applying the therapeutic compounds for the treatment of erectile dysfunction to the meatus of the glans penis.

Abstract: A treatment for male erectile dysfunction comprising separately storing a lyophilized composition of vasoactive agents and a carrier gel, mixing said lyophilized composition of vasoactive agents and said carrier gel creating a homogeneous mixture and applying said homogeneous mixture to the meatus of the glans penis. A system for the treatment of male erectile dysfunction comprising a syringe coupling system for the storage, mixing and application of therapeutic compounds for the treatment of erectile dysfunction, said system further comprising a first syringe and a second syringe. The first and second syringes are filled with a lyophilized composition of vasoactive agents or a carrier gel. The system includes a locking device coupling said syringes to facilitate the transfer of said lyophilized composition of vasoactive agents and carrier gel between the syringes and a penile adapter for applying the therapeutic compounds for the treatment of erectile dysfunction to the meatus of the glans penis.

Abstract: A treatment for male erectile dysfunction comprising separately storing a lyophilized composition of vasoactive agents and a carrier gel, mixing said lyophilized composition of vasoactive agents and said carrier gel creating a homogeneous mixture and applying said homogeneous mixture to the meatus of the glans penis. A system for the treatment of male erectile dysfunction comprising a syringe coupling system for the storage, mixing and application of therapeutic compounds for the treatment of erectile dysfunction, said system further comprising a first syringe and a second syringe. The first and second syringes are filled with a lyophilized composition of vasoactive agents or a carrier gel. The system includes a locking device coupling said syringes to facilitate the transfer of said lyophilized composition of vasoactive agents and carrier gel between the syringes and a penile adapter for applying the therapeutic compounds for the treatment of erectile dysfunction to the meatus of the glans penis.

Abstract: A hand-held flashlight comprising a metal halide arc lamp operating between 8 and 22 watts. The lamp has an arc gap of between 0.7 and 1.4 mm and a color temperature at or above 5000° Kelvin. The lamp contains a fill gas including mercury and indium in percentages to produce a point source of white light capable of penetrating dense smoke and fog. The flashlight includes a reflector containing the arc lamp and providing a collimated beam of high intensity white light. The flashlight includes a circuit for providing a high starting voltage to the lamp and a lower operating voltage after sustaining the lamp. The circuit includes a battery, a ballast, and a microprocessor for monitoring the lamp and the battery. The microprocessor provides a discernible output signal indicative of the lamp on-time and battery voltage. The microprocessor controls the application of the starting voltage from the ballast to the lamp to prevent misstarting of the lamp.

Abstract: A hand-held flashlight comprising a metal halide arc lamp operating between 8 and 22 watts. The lamp has an arc gap of between 0.7 and 1.4 mm and a color temperature at or above 5000° Kelvin. The lamp contains a fill gas including mercury and indium in percentages to produce a point source of white light capable of penetrating dense smoke and fog. The flashlight includes a reflector containing the arc lamp and providing a collimated beam of high intensity white light. The flashlight includes a circuit for providing a high starting voltage to the lamp and a lower operating voltage after sustaining the lamp. The circuit includes a battery, a ballast, and a microprocessor for monitoring the lamp and the battery. The microprocessor provides a discernible output signal indicative of the lamp on-time and battery voltage. The microprocessor controls the application of the starting voltage from the ballast to the lamp to prevent misstarting of the lamp.