Abstract: A pressure relief valve (PRV) assembly may include a housing having an opening therein, an interior cavity, a passageway extending between the opening and the interior cavity, and a flange extending within the passageway adjacent the opening. The PRV assembly may also include a first stage valve carried within the interior cavity, and a second stage valve fluidly coupled in series with the first stage valve. The second stage valve may include an enlarged head carried within the opening and a shaft extending from the enlarged head through the passageway to the interior cavity. The shaft may have a proximal end coupled to the enlarged head and an opposing enlarged distal end adjacent the interior cavity. A biasing member may be between the enlarged distal end and the flange. The biasing member may be configured to bias the first and second stage valves to a closed position.

Abstract: A pressure relief valve (PRV) assembly may include PRV stages coupled in end-to-end relation. Each PRV stage may include a PRV body having a cavity therein to receive an adjacent PRV body therein and a fluid passageway fluidly coupled to the cavity. Each PRV stage may also include a PRV valve carried within the cavity and extending within the fluid passageway, and a first biasing member carried within the cavity to bias the PRV valve. Each PRV stage may further include a biasing member stop coupled to the PRV valve within the fluid passageway, and a second biasing member held within the fluid passageway by the biasing member stop and biasing the PRV valve. An end cap may be coupled to a last PRV stage of the PRV stages to hold the first biasing member within the cavity.

Abstract: A pressure relief valve (PRV) assembly may include a housing having an opening therein, an interior cavity, a passageway extending between the opening and the interior cavity, and a flange extending within the passageway adjacent the opening. The PRV assembly may also include a first stage valve carried within the interior cavity, and a second stage valve fluidly coupled in series with the first stage valve. The second stage valve may include an enlarged head carried within the opening and a shaft extending from the enlarged head through the passageway to the interior cavity. The shaft may have a proximal end coupled to the enlarged head and an opposing enlarged distal end adjacent the interior cavity. A biasing member may be between the enlarged distal end and the flange. The biasing member may be configured to bias the first and second stage valves to a closed position.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: An electrode assembly for a myoelectric prosthesis allowing at least partial decoupling of the movement of the at least one electrode from the electrode housing case and from the prosthesis socket through the mounting of the at least one electrode using at least one biasing element. This allows the at least one electrode to be forced into contact with the patient in the target area using a moveable pressure application structure reducing/eliminating socket motion artifacts because the pressure is transferred toward the target area but the at least one electrode is not otherwise constrained to minimise or avoid the at least one electrode being dragged across the target area through the mounting to the prosthesis socket which causes socket motion artifacts.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A subsea vessel includes an outer layer of non-corrosive material and an inner layer of high-strength material that both corroborate in a subsea environment to withstand external pressure and prevent corrosion. The subsea vessel further includes a cavity surrounded by the inner layer and outer layer for providing storage in and protection from the subsea environment. The cavity is accessible via an opening that extends through the inner layer and the outer layer. The opening can be opened and closed with a cooperating cap that impermeably seals the cavity. The cap may include a number or connection mechanisms for being selectively secured to the opening. In addition, the cap may include a portion formed of a high-strength material and a portion formed of a non-corrosive material.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: A pressure relief valve is disclosed with a first stage valve that is in series with a second stage valve, with an enclosed cavity between the first stage valve and the second stage valve. The first stage valve relieves pressure from an enclosure into the enclosed cavity between the stages, when the pressure is above a cracking pressure of the first stage valve. The second stage relieves pressure from the enclosed cavity when the pressure is above the cracking pressure of the second stage valve.

Abstract: An installation and removal system for a toilet unit is provided. The system includes a base having floor engaging wheels coupled thereto. At least one of the floor engaging wheels is adjustable to maintain the base substantially level relative to the floor. An actuator is disposed on the base. A pair of spaced apart support elements are coupled to the actuator and adapted to engage an underside of the toilet unit. An angle of the support elements relative the base is adjustable. The system includes a retaining system coupled to the spaced apart support elements and adapted to couple with the toilet unit. The retaining system militate against an undesired movement of the toilet unit relative the support elements. A kit and method for using the system are also provided.

Abstract: An installation and removal system for a toilet unit is provided. The system includes a base having floor engaging wheels coupled thereto. At least one of the floor engaging wheels is adjustable to maintain the base substantially level relative to the floor. An actuator is disposed on the base. A pair of spaced apart support elements are coupled to the actuator and adapted to engage an underside of the toilet unit. An angle of the support elements relative the base is adjustable. The system includes a retaining system coupled to the spaced apart support elements and adapted to couple with the toilet unit. The retaining system militate against an undesired movement of the toilet unit relative the support elements. A kit and method for using the system are also provided.

Abstract: An installation and removal system for a toilet unit is provided. The system includes a base having floor engaging wheels coupled thereto. At least one of the floor engaging wheels is adjustable to maintain the base substantially level relative to the floor. An actuator is disposed on the base. A pair of spaced apart support elements are coupled to the actuator and adapted to engage an underside of the toilet unit. An angle of the support elements relative the base is adjustable. The system includes a retaining system coupled to the spaced apart support elements and adapted to couple with the toilet unit. The retaining system militate against an undesired movement of the toilet unit relative the support elements. A kit and method for using the system are also provided.

Abstract: Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —O— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.

Abstract: Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk— in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain —CH2—CH(R)—, —CH?C(R)— or in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —0— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof.

Abstract: Phenylalanine derivatives of formula (1) are described: wherein R is a carboxylic acid or a derivative thereof; L1 is a linker atom or group; Ar is an optionally substituted aromatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of alpha4 integrins to their ligands and are of use in the prophylaxis and treatment of immune or inflammatory disorders.

Abstract: Phenylalanine enamide derivatives of formula (1) are described: wherein R1 is a group Ar1L2Ar2Alk- in which: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a covalent bond or a linker atom or group; Ar2 is an optionally substituted arylene or heteroarylene group; and Alk is a chain in which R is a carboxylic acid (—CO2H) or a derivative or biostere thereof; X is an —O— or —S— atom or —N(R2)— group in which: Rx, Ry and Rz which may be the same or different is each a hydrogen atom or an optional substituent; or Rz is an atom or group as previously defined and Rx and Ry are joined together to form an optionally substituted spiro linked cycloaliphatic or heterocycloaliphatic group; and the salts, solvates, hydrates and N-oxides thereof. The compounds are able to inhibit the binding of integrins to their ligands and are of use in the prophylaxis and treatment of immuno or inflammatory disorders or disorders involving the inappropriate growth or migration of cells.