Patents by Inventor John Heap

John Heap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of selecting a polypeptide of interest
    Patent number: 12698521
    Abstract: The invention relates to methods for identifying polypeptides and polynucleotides of interest, be they novel or variant polypeptides and polynucleotides, by expressing a plurality of polypeptides in an obligate or facultative anaerobe that is incapable of, or displays a reduction in, the oxidation of NADH and/or NADPH under anaerobic fermentation conditions and selecting an obligate or facultative anaerobe that grows or displays a growth advantage under said conditions. The invention is also concerned with novel enzymes per se, and their use in enzymatic production processes.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: August 4, 2026
    Assignee: Imperial College Innovations Limited
    Inventors: Lara Selles Vidal, John Heap
  • METHOD OF SELECTING A POLYPEPTIDE OF INTEREST
    Publication number: 20210277441
    Abstract: The invention relates to methods for identifying polypeptides and polynucleotides of interest, be they novel or variant polypeptides and polynucleotides, by expressing a plurality of polypeptides in an obligate or facultative anaerobe that is incapable of, or displays a reduction in, the oxidation of NADH and/or NADPH under anaerobic fermentation conditions and selecting an obligate or facultative anaerobe that grows or displays a growth advantage under said conditions. The invention is also concerned with novel enzymes per se, and their use in enzymatic production processes.
    Type: Application
    Filed: June 19, 2019
    Publication date: September 9, 2021
    Applicant: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Lara Vidal, John Heap
  • Cover with gas permeable layer
    Patent number: 9895628
    Abstract: A holding tank cover includes a gas permeable insulating membrane and a gas impermeable cover layer sized to overlay and conceal the gas permeable membrane. Together, the gas permeable membrane and the gas impermeable cover layer facilitate a controlled transmission of gas between an interior of the holding tank and an environment external to the holding tank.
    Type: Grant
    Filed: May 2, 2016
    Date of Patent: February 20, 2018
    Assignee: Raven Industries, Inc.
    Inventors: John Heap, Andre Alan Harvey
  • COVER WITH GAS PERMEABLE LAYER
    Publication number: 20160243465
    Abstract: A holding tank cover includes a gas permeable insulating membrane and a gas impermeable cover layer sized to overlay and conceal the gas permeable membrane. Together, the gas permeable membrane and the gas impermeable cover layer facilitate a controlled transmission of gas between an interior of the holding tank and an environment external to the holding tank.
    Type: Application
    Filed: May 2, 2016
    Publication date: August 25, 2016
    Inventors: John Heap, Andre Alan Harvey
  • Cover with gas permeable layer
    Patent number: 9352249
    Abstract: A holding tank cover includes a gas permeable insulating membrane and a gas impermeable cover layer sized to overlay and conceal the gas permeable membrane. Together, the gas permeable membrane and the gas impermeable cover layer facilitate a controlled transmission of gas between an interior of the holding tank and an environment external to the holding tank.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: May 31, 2016
    Assignee: Colorado Lining International, Inc.
    Inventors: John Heap, Andre Alan Harvey
  • BACTERIAL EXPRESSION SYSTEM
    Publication number: 20150056168
    Abstract: The present invention provides a bacterial expression system for expressing a nucleic acid comprising: (a) DNA encoding a group 5 RNA polymerase sigma factor; and (b) an expression cassette comprising a promoter recognised by the group 5 RNA polymerase sigma factor operably linked to a heterologous nucleic acid; wherein (a) and (b) are located on the same expression vector, separate expression vectors or are integrated into the bacterial host genome.
    Type: Application
    Filed: March 28, 2013
    Publication date: February 26, 2015
    Inventors: Nigel Peter Minton, Ying Zhang, Katrin Schwarz, John Heap
  • COVER WITH GAS PERMEABLE LAYER
    Publication number: 20150000521
    Abstract: A holding tank cover includes a gas permeable insulating membrane and a gas impermeable cover layer sized to overlay and conceal the gas permeable membrane. Together, the gas permeable membrane and the gas impermeable cover layer facilitate a controlled transmission of gas between an interior of the holding tank and an environment external to the holding tank.
    Type: Application
    Filed: July 1, 2014
    Publication date: January 1, 2015
    Inventors: John Heap, Andre Alan Harvey