Patents by Inventor John Helmann

John Helmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for screening antibacterial compounds
    Publication number: 20050186653
    Abstract: The present invention pertains to compositions and methods used to ascertain if putative antibiotics trigger a cell envelope stress response in bacterial organisms. In one aspect of the invention, three two-component systems are described: LiaR & LiaS (formerly YvqCE); YvcP & YvcQ; and BceR & BceS (formerly YtsAB). These systems, for example, can be used to analyze antibiotics such as vancomycin, bacitracin, nisin, and ramoplanin, which interfere with the lipid II cycle in the cytoplasmic membrane.
    Type: Application
    Filed: June 23, 2004
    Publication date: August 25, 2005
    Applicant: Cornell Research Foundation, Inc.
    Inventors: John Helmann, Thorsten Mascher