Abstract: Disclosed herein are polynucleotides comprising a first nucleic acid encoding a first pathogen antigen and, optionally, a second nucleic acid encoding a second pathogen antigen, and, optionally, a nucleic acid encoding an immune modifier. In some aspects, the first pathogen antigen is a SARS-CoV-2 spike protein or antigenic fragment thereof. In some aspects, the second pathogen antigen is a SARS-CoV-2 protein or an antigenic fragment thereof. In some aspects, polynucletide includes two or more different immune modifiers. Also disclosed herein are vectors, compositions, pharmaceutical compositions, vaccines, lyophilized compositions, and cells comprising such polynucleotides. Methods of production and therapeutic use are also disclosed herein.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: A processor assembly including: an exposure station operable to expose a sample on a slide; a print station operable to apply a reagent to the exposed sample through a thermal inkjet process; and a robotic transfer mechanism to transfer the slide from the exposure station to the print station. Also, a reagent cartridge including: a body defining a container having a volume therein; a nonmetallic bag in the container operable to contain a reagent; and a printhead at a base of the body, the printhead coupled to an outlet of the bag. Further, a method including exposing a sample on a slide in a processor assembly; robotically transferring the slide to a printing station of the processor assembly; and applying a reagent to the exposed sample at the printing station by a thermal inkjet printing process.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: The disclosed technology includes device, systems, and methods for detecting an analyte using a biosensor. In some implementations, the biosensor may be a transdermal biosensor including a housing material, a nanocellulose material disposed within the housing material, an enzyme entrapped within the nanocellulose material that produces a chemical or biological product when exposed to a vapor or liquid, and a luminescent material within the nanocellulose material that emits visible light upon a chemical or biological reaction with the chemical or biological product.

Abstract: A gauge for a hybrid pressure and flowgauge regulator includes first indicia and second indicia. The first indicia provides an indication of a flow rate of a gas exiting an outlet of the hybrid pressure and flowgauge regulator when the gas exits with a pressure below a gauge threshold pressure. The second indicia provides an indication of the pressure of the gas exiting the outlet of the hybrid pressure and flowgauge regulator when the pressure of the gas exiting the outlet is above the gauge threshold pressure.

Abstract: An apparatus for micromanipulation of biological material, includes a vessel (1) having a reservoir (2) wherein the vessel has a channel (3) formed in a portion of the reservoir, the channel including an intermediate restriction (4) dimensioned to resist passage of the biological material but allow passage of liquid treatment solutions.

Abstract: An apparatus comprises a horizontal array of emitter/detector pairs; an array of lens pairs mounted above and aligned with emitter/detector pairs; and a first curved reflective surface positioned such that for each emitter/detector pair and corresponding lens pair, light from the emitter that passes through a lens of the lens pair is redirected into the far field, and light arriving from the far field is redirected through the other lens of the lens pair onto the detector. Light from each emitter is emitted upwards along a vertical axis, and light received by each detector is incident on the detector downwards along a vertical axis. If light emitted from the first array and reflected by the first surface into the far field reflects off an object in the far field and returns to the apparatus, the returning light is reflected off the first surface and detected by the first array.

Abstract: A boom conveyor includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a leveling mechanism that is configured to apply a leveling adjustment to the operator platform.

Abstract: A boom conveyor apparatus includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a levelling mechanism that is configured to apply a levelling adjustment to the operator platform.

Abstract: The disclosed technology includes device, systems, and methods for detecting an analyte using a biosensor. In some implementations, the biosensor may be a transdermal biosensor including a housing material, a nanocellulose material disposed within the housing material, an enzyme entrapped within the nanocellulose material that produces a chemical or biological product when exposed to a vapor or liquid, and a luminescent material within the nanocellulose material that emits visible light upon a chemical or biological reaction with the chemical or biological product.

Abstract: A gauge for a hybrid pressure and flowgauge regulator includes first indicia and second indicia. The first indicia provides an indication of a flow rate of a gas exiting an outlet of the hybrid pressure and flowgauge regulator when the gas exits with a pressure below a gauge threshold pressure. The second indicia provides an indication of the pressure of the gas exiting the outlet of the hybrid pressure and flowgauge regulator when the pressure of the gas exiting the outlet is above the gauge threshold pressure.

Abstract: A boom conveyor apparatus includes a boom that carries a conveyor, a support structure for the boom, a rear pivot joint that connects a rear end of the boom to the support structure, and a pivot drive that controls pivoting movement of the boom about the rear pivot joint. The boom conveyor apparatus includes an operator platform and an attachment mechanism at a front end of the boom whereby the operator platform may be attached to the boom or detached therefrom. The attachment mechanism includes a levelling mechanism that is configured to apply a levelling adjustment to the operator platform.

Abstract: A hybrid pressure and flowguage regulator apparatus includes a regulator body, an inlet, and an outlet assembly. The outlet assembly includes a first orifice of a first size, a second orifice of a second size that is larger than the first size, and a mechanism that automatically moves the first orifice between a first position and a second position. When the first orifice is in the first position, the flow of gas passes through both the first orifice and second orifice. When the first orifice is in the second position, the flow of gas bypasses the first orifice and flows through the second orifice with a specific flow rate or a second pressure that is less than the first pressure. The apparatus may also include a gauge that provides a visual indication of both the specific flow rate and the second pressure.

Abstract: A method of analysing a sample taken from a dialysis patient for the presence of microorganisms, said method comprising the steps of: (i) contacting the sample with (I) a first reporting means comprising: (a1) an indicator compound; and (b1) media and/or nutrients that support or encourage microbial growth; and (ii) examining the reporting means.

Abstract: An apparatus for micromanipulation of biological material, includes a vessel (1) having a reservoir (2) wherein the vessel has a channel (3) formed in a portion of the reservoir, the channel including an intermediate restriction (4) dimensioned to resist passage of the biological material but allow passage of liquid treatment solutions.

Abstract: A method of cryopreservation of biological material includes the steps of providing an apparatus including a vessel having a reservoir wherein the vessel has a channel formed in a portion of the reservoir, the channel including an intermediate restriction dimensioned to resist passage of the biological material but allow passage of liquid treatment solutions, and the channel including sub-reservoirs at either end of the restriction; introducing the biological material into a reservoir region of the apparatus for capture in a channel region of the vessel; irrigating and draining the biological material with a series of vitrification solutions introduced into a first of the sub-reservoirs and removed from a second of the sub-reservoirs; final draining the irrigation solutions from the vessel; and vitrifying the vessel and captive biological material.