Patents by Inventor John Henrik Johansen

John Henrik Johansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DYE COMPOSITIONS AND DYE SYNTHESES
    Publication number: 20130121926
    Abstract: The present invention relates to sulfonated optical dye compositions, especially dyes suitable for biological applications in vitro, and for in vivo imaging. Improved dye compositions and intermediates are provided, which enable the suppression of undesirable newly-identified impurities. Also provided is the use of the improved dye compositions in the preparation of conjugates with biological targeting molecules.
    Type: Application
    Filed: June 29, 2011
    Publication date: May 16, 2013
    Applicant: GE HEALTHCARE AS
    Inventors: Radha Achanath, Srinath Balaji, John Henrik Johansen
  • COMPOUNDS COMPRISING PARAMAGNETIC CHELATES ARRANGED AROUND A CENTRAL CORE AND THEIR USE IN MAGNETO RESONANCE IMAGING AND SPECTROSCOPY
    Publication number: 20110038805
    Abstract: The present invention relates to novel compounds of formula (I) and (II), compositions comprising compounds of formula (II) and their use as contrast agents in magnetic resonance (MR) imaging (MRI) and MR spectroscopy (MRS).
    Type: Application
    Filed: April 17, 2009
    Publication date: February 17, 2011
    Inventors: Andreas Meijer, Oskar Axelsson, Anders Brathe, Andreas Olsson, John Henrik Johansen, Duncan George Wynn
  • AROMATIC MULTIMERS
    Publication number: 20100008864
    Abstract: The present invention relates to novel compounds of formula (I) and (II), compositions comprising compounds of formula (II) and their use as contrast agents in magnetic resonance (MR) imaging (MRI) and MR spectroscopy (MRS).
    Type: Application
    Filed: July 8, 2009
    Publication date: January 14, 2010
    Inventors: Andreas Meijer, Harry John Wadsworth, Ian Martin Newington, Clare L. Jones, Amanda Ewan, Dennis O'Shea, Oskar Axelsson, Anders Brathe, Andreas Olsson, John Henrik Johansen, Duncan George Wynn
  • AUTOMATED METHOD
    Publication number: 20090155167
    Abstract: The present invention provides an automated method for the preparation of 99mTc radiopharmaceutical compositions, together with disposable cassettes for use in the method. The use of an automated synthesizer apparatus in the preparation of 99mTc radiopharmaceuticals is also described. Also described is the use of kits for the preparation of 99mTc radiopharmaceuticals in the method and disposable cassettes of the present invention.
    Type: Application
    Filed: October 9, 2006
    Publication date: June 18, 2009
    Applicant: GE HEALTHCARE LIMITED
    Inventors: Nigel Anthony Powell, Peter Stewart Weisner, Ian Anthony Sargeant, Torgrim Engell, John Henrik Johansen
  • Microbubble-based contrast agents with crosslinked and reduced proteinaceous shells
    Patent number: 5718884
    Abstract: The present invention pertains to proteinaceous gas- or gas precursor-containing microbubble contrast agents for use in ultrasound and/or MR imaging, in which the protein matrix is crosslinked by reaction with a bifunctional aldehyde (e.g., a dialdehyde such as glutaraldehyde or an .alpha.,.beta.-unsaturated aldehyde such as acrolein) in an aqueous medium at substantially neutral pH. The contrast agents exhibit improved in vivo and storage stabilities, particularly if the matrix is also reacted with a Schiff's base reducing agent such as a borohydride. Modification of the size distribution of such crosslinked proteinaceous gas-containing contrast agents, e.g. to reduce the mean size of the microbubbles, further enhances their stability and permits preparation of novel contrast agents having a particularly narrow microbubble size distribution.
    Type: Grant
    Filed: May 4, 1995
    Date of Patent: February 17, 1998
    Assignee: Nycomed Imaging AS
    Inventors: Jo Klaveness, Pal Rongved, John Henrik Johansen, Per Antonius Foss, Anders H.o slashed.gset, Anne Marie Hvoslef