Patents by Inventor John Hess

John Hess has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240180147
    Abstract: A whole blood storage system that includes whole blood leukoreduction with pH optimization for improved RBC storage. Such a system can provide leukoreduced whole blood for field medical use, but would preserve the RBCs and most plasma coagulation activity for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks so that the units would not go to waste.
    Type: Application
    Filed: April 7, 2022
    Publication date: June 6, 2024
    Applicant: Hemerus Medical, LLC
    Inventors: John HESS, Majid ZIA
  • Publication number: 20190160092
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 30, 2019
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Patent number: 10179145
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: January 15, 2019
    Assignees: University of Maryland, College Park, University of Maryland, Baltimore
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Publication number: 20160206777
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Application
    Filed: January 19, 2016
    Publication date: July 21, 2016
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Publication number: 20150175718
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Application
    Filed: January 13, 2015
    Publication date: June 25, 2015
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Publication number: 20150175714
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Application
    Filed: January 13, 2015
    Publication date: June 25, 2015
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Patent number: 8932560
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: January 13, 2015
    Assignees: University of Maryland, College Parke, University of Maryland, Baltimore
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Publication number: 20140337323
    Abstract: Methods and computing systems for generating and operating a searchable consumer market research (CMR) knowledge repository are provided. In one example, a method for generating a searchable CMR knowledge repository includes: (i) obtaining CMR data associated with one or more CMR studies; (ii) classifying the CMR data as at least one of: one or more CMR quantitative data files, one or more CMR summary files, and one or more CMR associated files; and (iii) storing a first portion of the CMR data in a first data storage repository and a second portion of the CMR data in a second data storage repository based on the classification in order to generate the searchable CMR knowledge repository.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 13, 2014
    Inventors: Andrew Soep, Kristi Zuhlke-Kimball, John Hess
  • Patent number: 8077004
    Abstract: An electrical device is produced by winding wires around a core. The device may be used as a transformer. Wires are inserted into, through and around a first hole and a first side of a core a desired number of times. Thereafter, the wires are extended along either a top or a bottom of the core and then passed through and around a second hole of the core. After the wires are wound around the second hole of the core and a second side of the core, the production of the device is complete.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: December 13, 2011
    Assignee: Bel Fuse (Macao Commercial Offshore) Limited
    Inventors: Brian J. Buckmeier, John Hess, Edwin Edralin, Joseph Berry
  • Patent number: 7924130
    Abstract: An isolation magnetic device produced by inserting a first end of a wire through a first hole of a core, wrapping the first end of the wire around a first side of the core and inserting the first end of the wire through a second hole of the core. The second hole of the core is spaced from the first hole and has a longitudinal axis extending parallel to a longitudinal axis of the first hole. The device is further produced by inserting a second end of the wire through the second hole of the core, wrapping the second end of the wire around the first side of the core and inserting the second end of the wire through the first hole of the core.
    Type: Grant
    Filed: August 20, 2008
    Date of Patent: April 12, 2011
    Inventors: Brian J. Buckmeier, John Hess, Joseph Berry, Edwin Edralin
  • Publication number: 20110001596
    Abstract: An electrical device is produced by winding wires around a core. The device may be used as a transformer. Wires are inserted into, through and around a first hole and a first side of a core a desired number of times. Thereafter, the wires are extended along either a top or a bottom of the core and then passed through and around a second hole of the core. After the wires are wound around the second hole of the core and a second side of the core, the production of the device is complete.
    Type: Application
    Filed: August 4, 2010
    Publication date: January 6, 2011
    Applicant: Bel Fuse (Macao Commercial Offshore) Limited
    Inventors: Brian J. Buckmeier, John Hess, Edwin Edralin, Joe Berry
  • Publication number: 20100045420
    Abstract: An isolation magnetic device produced by inserting a first end of a wire through a first hole of a core, wrapping the first end of the wire around a first side of the core and inserting the first end of the wire through a second hole of the core. The second hole of the core is spaced from the first hole and has a longitudinal axis extending parallel to a longitudinal axis of the first hole. The device is further produced by inserting a second end of the wire through the second hole of the core, wrapping the second end of the wire around the first side of the core and inserting the second end of the wire through the first hole of the core.
    Type: Application
    Filed: August 20, 2008
    Publication date: February 25, 2010
    Inventors: Brian J. Buckmeier, John Hess, Joseph Berry, Edwin Edralin
  • Publication number: 20090062849
    Abstract: A hemostatic tissue sealant sponge and a spray for acute wounds are disclosed. The sponge comprises hydrophobically modified polymers that anchor themselves within the membrane of cells in the vicinity of the wound. The seal is strong enough to substantially prevent the loss of blood inside the boundaries of the sponge, yet weak enough to substantially prevent damage to newly formed tissue upon recovery and subsequent removal of the sponge. In examples, the polymers inherently prevent microbial infections and are suitable for oxygen transfer required during normal wound metabolism. The spray comprises hydrophobically modified polymers that form solid gel networks with blood cells to create a physical clotting mechanism to prevent loss of blood. In an example, the spray further comprises at least one reagent that increases the mechanical integrity of the clot. In another example, the reagent prevents microbial infection of the wound.
    Type: Application
    Filed: September 4, 2008
    Publication date: March 5, 2009
    Inventors: Matthew Dowling, John Hess, Grant Bochicchio, Srinivasa Raghavan
  • Patent number: 7429195
    Abstract: An electric device capable of handling high speed data communication and which could be used with, for example, a connector application such as an RJ45 type connector. The electric device is formed by inserting at least one wire through a first hole in a core, wrapping the wire around a side of the core, and inserting the wire through a second hole in the core a desired number of times. A common mode choke may be combined with the electric device. To form such a choke, two of the wires from the electric device may be wrapped around a second core in the same fashion a desired number of times.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: September 30, 2008
    Inventors: Brian J. Buckmeier, John Hess, Edwin Edralin, Joe Berry
  • Publication number: 20080197959
    Abstract: An electric device capable of handling high speed data communication and which could be used with, for example, a connector application such as an RJ45 type connector. The electric device is formed by inserting at least one wire through a first hole in a core, wrapping the wire around a side of the core, and inserting the wire through a second hole in the core a desired number of times. A common mode choke may be combined with the electric device. To form such a choke, two of the wires from the electric device may be wrapped around a second core in the same fashion a desired number of times.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 21, 2008
    Inventors: Brian J. Buckmeier, John Hess, Edwin Edralin, Joe Berry
  • Publication number: 20080200060
    Abstract: An electrical device is produced by winding wires around a core. The device may be used as a transformer. Wires are inserted into, through and around a first hole and a first side of a core a desired number of times. Thereafter, the wires are extended along either a top or a bottom of the core and then passed through and around a second hole of the core. After the wires are wound around the second hole of the core and a second side of the core, the production of the device is complete.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 21, 2008
    Inventors: Brian J. Buckmeier, John Hess, Edwin Edralin, Joe Berry
  • Publication number: 20070269424
    Abstract: Moraxella bovis cytotoxin, cytotoxin gene, antibodies and vaccines for prevention and treatment of Moraxella bovis infections Moraxella bovis cytotoxin and a gene encoding Moraxella bovis cytotoxin. Identification, isolation, cloning and identification of nucleotide sequence of the Moraxella bovis genes mbxA, mbxB, mbxC and mbxD, partial purification of the native cytotoxin, preparation of partially purified native and a recombinant Moraxella bovis cytotoxin, identification of an amino acid sequence of the cytotoxin, preparation of antibodies against the Moraxella bovis cytotoxin, preparation of vaccines against Moraxella bovis. Method for prevention and treatment of infectious bovine keratoconjunctivitis caused by Moraxella bovis.
    Type: Application
    Filed: March 16, 2007
    Publication date: November 22, 2007
    Applicant: The Regents of the University of California
    Inventors: Lisle George, John Angelos, John Hess
  • Publication number: 20070094708
    Abstract: An electronic device may be remotely activated by an activation utility, such as a remote start-up utility. The remote utility may be initiated in response to activation of a security system. The security system may generate an electronic signal which initiates the remote utility. The remote utility sends activation instructions to the device. The device may perform the activation tasks while a user is moving from the security system location to the device location.
    Type: Application
    Filed: October 26, 2005
    Publication date: April 26, 2007
    Inventor: John Hess
  • Publication number: 20070080177
    Abstract: Components are provided for use in systems for dispensing fluids. A resilient diaphragm is provided for a diaphragm pump. The diaphragm includes a pressurizing portion connected with a connecting member to a peripheral mounting flange for mounting the diaphragm in the housing of the pump. The pump housing has a retention wall which can be swaged against the diaphragm flange. The pump housing has a discharge structure with an outlet valve and a restraint structure adjacent the valve to prevent in-venting through the outlet valve. The outlet valve includes a flange which is retained by a retention wall and which projects from the discharge structure and which is swaged into engagement with the outlet valve flange.
    Type: Application
    Filed: December 6, 2006
    Publication date: April 12, 2007
    Inventors: Jason Hatton, Steven Tuckey, John Hess
  • Publication number: 20070011757
    Abstract: Transgenic rats are generated which incorporate a primate B1 bradykinin receptor transgene(s) into their genome. This B1 bradykinin receptor gene is expressed in these transgenic rats, which results in binding of compounds which are selective for the primate form (such as the human form) of the receptor and not the rat form of the receptor. Therefore, the expressed transgenes within these transgenic lines mimic antagonist and agonist selectivity of the wild type primate B1 bradykinin receptor. These transgenic animals are useful as a specific receptor occupancy model for modulators of the B1 bradykinin receptor from the human or closely related species, as well as providing for an animal model system for assessment of the pharmacodynamic properties of such a B1 bradykinin modulator(s).
    Type: Application
    Filed: May 16, 2006
    Publication date: January 11, 2007
    Inventors: John Hess, Robert Gould, Douglas Pettibone