Patents by Inventor John Higson
John Higson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8758816Abstract: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent.Type: GrantFiled: September 29, 2009Date of Patent: June 24, 2014Assignee: Meda Pharmaceuticals Inc.Inventors: Dennis Fuge, John Higson, Bryan A. Roecklein, Gul Balwani, Alexander D. D'Addio
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Patent number: 8567452Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: GrantFiled: July 17, 2012Date of Patent: October 29, 2013Assignee: Nordson CorporationInventors: Henry Digregorio, John Higson, Jeffery White
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Publication number: 20120279998Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: ApplicationFiled: July 17, 2012Publication date: November 8, 2012Applicant: NORDSON CORPORATIONInventors: Henry DiGregorio, John Higson, Jeffery White
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Patent number: 8241544Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: GrantFiled: March 10, 2010Date of Patent: August 14, 2012Assignee: Nordson CorporationInventors: Henry DiGregorio, John Higson, Jeffery White
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Publication number: 20100163574Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: ApplicationFiled: March 10, 2010Publication date: July 1, 2010Applicant: NORDSON CORPORATIONInventors: Henry DiGregorio, John Higson, Jeffery White
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Publication number: 20100152147Abstract: The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or more additional active agents. Preferred such compositions further comprise one or more pharmaceutically acceptable carriers or excipients that reduce the amount of post-nasal drip, and/or that minimize or mask the unpleasant bitter taste associated with post-nasal drip, of the compositions into the oral cavity, upon intranasal or ocular administration of the compositions. Especially effective excipients used in the compositions of the present invention are hypromellose as a viscosity modifier and sucralose as a taste-masking agent.Type: ApplicationFiled: September 29, 2009Publication date: June 17, 2010Inventors: Dennis Fuge, John Higson, Bryan A. Roecklein, Gul Balwani, Alexander D. D'Addio
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Patent number: 7677419Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: GrantFiled: April 21, 2004Date of Patent: March 16, 2010Assignee: Nordson CorporationInventors: Henry DiGregorio, John Higson, Jefferey White
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Publication number: 20090137423Abstract: A method of fabricating a micro-electrode array comprising the steps of coating an electrode with an insulating polymer coating by screen printing an insulating polymer onto the electrode and then curing said polymer; and sonically ablating the insulating polymer coating to produce a plurality of micro-pores.Type: ApplicationFiled: April 28, 2005Publication date: May 28, 2009Inventor: Seamus Patrick John Higson
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Publication number: 20050236063Abstract: A syringe for holding fluids susceptible to void formation when frozen and thawed before use. The interior surface of the syringe sidewall may be roughened, which serves to prevent or significantly reduce the incidence of void formation in the fluid. The required level of surface roughening for counteracting void formation may be reduced by increasing the sidewall flexibility. Alternatively, the flexibility of the syringe sidewall may operate over certain thickness ranges to prevent or significantly reduce void formation in the fluid without intentionally roughening the interior surface.Type: ApplicationFiled: April 21, 2004Publication date: October 27, 2005Applicant: Nordson CorporationInventors: Henry DiGregorio, John Higson, Jeffery White
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Patent number: 6083366Abstract: There is disclosed a sensor for an analyte comprising a working electrode assembly, itself comprising a micro-electrode array in which each micro-electrode is coated with a layer of redox state dependent conducting organic polymer, a counter electrode; a conductive medium containment into which the electrodes are disposed and a material for analysis may be introduced; means for applying an alternating electric polarizing potential across the electrodes; and means for detecting a variation in a conductimetric property across the {working electrode.fwdarw.counter electrode} plane in the presence of the analyte.Type: GrantFiled: October 17, 1997Date of Patent: July 4, 2000Assignee: The Manchester Metropolitan UniversityInventor: Seamus Patrick John Higson