Abstract: Example deflectable catheter systems are described. An example deflectable catheter system includes a housing, an orienting member, an actuator, a first elongate member, a second elongate member, and a wire member. The housing defines a passageway. The orienting member is attached to the housing. The actuator is attached to the orienting member and is moveable between an actuator first position and an actuator second position. The first elongate member is attached to the orienting member and defines a lumen. The first elongate member is moveable between a first, substantially straight configuration when the actuator is in the actuator first position and a second, curved configuration when the actuator is in the actuator second position. The second elongate member is disposed through the passageway of the housing and extends through the lumen defined by the first elongate member. The second elongate member is rotatable relative to the first elongate member.

Abstract: Drug delivery device, comprising a needle, which a distal end and a proximal end comprises an inner surface forming a channel, an outer surface, a first salient located on the outer surface.

Abstract: A drive member and a rotation member are rotatable with respect to a housing. The drive member comprises drive fingers, which are resilient or resiliently mounted. A slider is disposed at the drive member and is axially movable between a first position, in which the slider keeps the drive fingers constrained, and a second position, in which the drive fingers are released. A unidirectional rotational clutch engages the drive member with the rotation member. The clutch is formed by the drive fingers when the slider is in the first position. The drive member and the rotation member are disengaged when the slider is in the second position. The slider is in the first position when a unit is attached to the housing, and in the second position when the unit is removed.

Abstract: A needle assembly (2) for a drug delivery device (1) comprises a needle seal (3), a needle retainer (4) and a needle (5). The needle retainer (4) secures the needle (5) against displacement with respect to said needle retainer (4) when a dose of drug is being delivered. The needle seal (3) is configured to push onto the needle retainer (4) after delivering the dose of the drug, thereby unlocking the needle (5) from the needle retainer (4).

Abstract: A method for assisting in the coupling of a semi-trailer to a turntable of a prime mover includes remotely monitoring sensors about the turntable to make a number of determinations. These include that the semitrailer is suitably close to the turntable for correct coupling. That a locking member, e.g. a kingpin, of the semitrailer is correctly positioned relative to the turntable for proper coupling. That a kingpin locking mechanism of the turntable is in a locked configuration. The result of the determinations is indicated to an operator of the prime mover.

Abstract: A collapsible steering column assembly for a vehicle comprises a shroud which surrounds a steering column shaft, a mounting bracket secured to or integral with a fixed part of the vehicle, a support bracket secured to the mounting bracket through one or more frangible connectors, a clamp mechanism which releasably secures the shroud to the support bracket, and a blocking part which is fixed in position relative to the mounting and at least in an unclamped condition of the clamp mechanism provides an additional force path between the clamp mechanism and the mounting bracket that does not pass through the support bracket. In the event that an axial load is applied to the steering assembly when the clamp mechanism is unlocked and has reached the end of its allowable travel at least some of the load is carried through the clamp mechanism and the blocking part to the mounting bracket along the additional force path.

Abstract: A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface.

Abstract: A drug delivery device for dispensing of a dose of a medicinal product, comprising a holder (14) for a product-containing cartridge (16), the cartridge (16) having a piston (18) slidably arranged therein in an axial direction, a piston rod (12) to be operably engaged with the cartridge's piston (18) for dispensing of a dose of the medicinal product, and at least one spacer (20) being selected according to a relative distance between piston (18) and piston rod (12) and being disposed between the piston rod (12) and the piston (18) for eliminating axial clearance between piston (18) and piston rod (12).

Abstract: A collapsible steering column assembly for a vehicle comprises a shroud which surrounds a steering column shaft, a mounting bracket secured to or integral with a fixed part of the vehicle, a support bracket secured to the mounting bracket through one or more frangible connectors, a clamp mechanism which releasably secures the shroud to the support bracket, and a blocking part which is fixed in position relative to the mounting and at least in an unclamped condition of the clamp mechanism provides an additional force path between the clamp mechanism and the mounting bracket that does not pass through the support bracket. In the event that an axial load is applied to the steering assembly when the clamp mechanism is unlocked and has reached the end of its allowable travel at least some of the load is carried through the clamp mechanism and the blocking part to the mounting bracket along the additional force path.

Abstract: Described is a needle safety device comprising a needle hub, a needle coupled to the needle hub and having a distal tip, a sleeve coupled to the needle hub, a needle shield telescopically coupled to the sleeve; and a needle disabling mechanism coupled to the needle. In a first axial position, the needle shield covers the distal tip of the needle and the needle disabling mechanism is in a first angular position. In a retracted position, the needle shield is retracted relative to the needle exposing the distal tip of the needle. In a second axial position, the needle shield is distal of the first axial position and the needle disabling mechanism is in a second angular position bending the needle.

Abstract: Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into an adhesion connection.

Abstract: Described is a guide device for intraocular injection comprising a base plate having an inner surface and an outer surface, a handle formed on the outer surface, and a hole formed in the base plate and extending through the inner and outer surfaces. The inner surface is adapted to contact an eye ball.

Abstract: Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into a vacuum connection.

Abstract: A seal member is configured to seal a chamber of a drug delivery device which is suitable to contain a drug, wherein the seal member comprises a diaphragm.

Abstract: A keying insert for use with a cartridge assembly containing a fluid. The insert comprises a main body defining a bore that extends from a proximal end to a distal end of the main body and allows the fluid to dispense from the distal end of the cartridge through a septum. The main body includes a septum for sealing the fluid within the cartridge and a coding feature that is keyed to a cartridge holder or other dispense interface.

Abstract: A drive member and a rotation member are rotatable with respect to a housing. The drive member comprises drive fingers, which are resilient or resiliently mounted. A slider is disposed at the drive member and is axially movable between a first position, in which the slider keeps the drive fingers constrained, and a second position, in which the drive fingers are released. A unidirectional rotational clutch engages the drive member with the rotation member. The clutch is formed by the drive fingers when the slider is in the first position. The drive member and the rotation member are disengaged when the slider is in the second position. The slider is in the first position when a unit is attached to the housing, and in the second position when the unit is removed.

Abstract: A drug delivery device for dispensing of a dose of a medicinal product, comprising a holder (14) for a product-containing cartridge (16), the cartridge (16) having a piston (18) slidably arranged therein in an axial direction, a piston rod (12) to be operably engaged with the cartridge's piston (18) for dispensing of a dose of the medicinal product, and at least one spacer (20) being selected according to a relative distance between piston (18) and piston rod (12) and being disposed between the piston rod (12) and the piston (18) for eliminating axial clearance between piston (18) and piston rod (12).

Abstract: Drug delivery device, comprising a needle, which a distal end and a proximal end comprises an inner surface forming a channel, an outer surface, a first salient located on the outer surface.

Abstract: A needle assembly (2) for a drug delivery device (1) comprises a needle seal (3), a needle retainer (4) and a needle (5). The needle retainer (4) secures the needle (5) against displacement with respect to said needle retainer (4) when a dose of drug is being delivered. The needle seal (3) is configured to push onto the needle retainer (4) after delivering the dose of the drug, thereby unlocking the needle (5) from the needle retainer (4).

Abstract: Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into a vacuum connection.