Abstract: A rotating detonation combustor (RDC) and an associated system is disclosed herein. The RDC can be operably coupled with a vehicle to provide additional power capability over the primary motive power source. The RDC can be operated on demand to provide power to a turbine connected to an electrical power generator in some forms. The RDC can be used in stationary systems as well as moving vehicle systems.

Abstract: A rotating detonation combustor (RDC) and an associated system is disclosed herein. The RDC can be operably coupled with a vehicle to provide additional power capability over the primary motive power source. The RDC can be operated on demand to provide power to a turbine connected to an electrical power generator in some forms. The RDC can be used in stationary systems as well as moving vehicle systems.

Abstract: Articles of footwear, including athletic footwear, include one or more of: (a) a sole structure; (b) an upper having lateral and medial side elements engaged with the sole structure, the upper made from a polymer matrix structure that extends through at least a heel region; (c) a size adjustment mechanism located at the heel region; (d) a heel tongue element located adjacent the size adjustment mechanism; (e) a shoe securing mechanism; (f) an instep tongue member; and/or (g) a bootie member located at least partially within the foot-receiving chamber. Methods of manufacturing such articles of footwear also are disclosed.

Abstract: Articles of footwear, including athletic footwear, include one or more of: (a) a sole structure; (b) an upper having lateral and medial side elements engaged with the sole structure, the upper made from a polymer matrix structure that extends through at least a heel region; (c) a size adjustment mechanism located at the heel region; (d) a heel tongue element located adjacent the size adjustment mechanism; (e) a shoe securing mechanism; (f) an instep tongue member; and/or (g) a bootie member located at least partially within the foot-receiving chamber. Methods of manufacturing such articles of footwear also are disclosed.

Abstract: An article of footwear is disclosed that includes an upper and a sole structure. The upper includes a matrix structure that defines a plurality of apertures. The apertures may have an elongate configuration to impart differences in the extensibility of the upper in different directions. For example, the matrix layer may be formed from a plurality of segments that cross each other to define the apertures. A method of manufacturing the article of footwear is also disclosed.

Abstract: Articles of footwear, including athletic footwear, include one or more of: (a) a sole structure; (b) an upper having lateral and medial side elements engaged with the sole structure, the upper made from a polymer matrix structure that extends through at least a heel region; (c) a size adjustment mechanism located at the heel region; (d) a heel tongue element located adjacent the size adjustment mechanism; (e) a shoe securing mechanism; (f) an instep tongue member; and/or (g) a bootie member located at least partially within the foot-receiving chamber. Methods of manufacturing such articles of footwear also are disclosed.

Abstract: An oral dosage form comprising a first composition and a second composition, each composition comprising a pharmaceutically acceptable weak base, especially Compound A or a pharmaceutically acceptable salt or solvate thereof, (‘the drug’) and a pharmaceutically acceptable carrier therefor, wherein the first and second compositions are arranged to release drug at differing release rates on administration such that the rate of release of the drug from the dosage form is substantially independent of pH; a process for preparing such a dosage form and the use of such a dosage form in medicine.

Abstract: An article of footwear is disclosed that includes an upper and a sole structure. The upper includes a matrix structure that defines a plurality of apertures. The apertures may have an elongate configuration to impart differences in the extensibility of the upper in different directions. For example, the matrix layer may be formed from a plurality of segments that cross each other to define the apertures. A method of manufacturing the article of footwear is also disclosed.