Patents by Inventor John Howard Hutchinson

John Howard Hutchinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110039852
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: January 29, 2009
    Publication date: February 17, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott, Yen Pham Truong, Jeffrey Roger Roppe, Nicholas Simon Stock, Jeannie M. Arruda, Thomas Jon Seiders, Bowei Wang, Deborah Volkots
  • Publication number: 20110034514
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: October 18, 2010
    Publication date: February 10, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe
  • Publication number: 20110021573
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the antagonists of PGD2 receptors described herein, as well as methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: February 25, 2009
    Publication date: January 27, 2011
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Thomas Jonathan Seiders, Jill Melissa Scott, Jeannie M. Arruda, Bowei Wang
  • Publication number: 20100311799
    Abstract: Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
    Type: Application
    Filed: June 3, 2010
    Publication date: December 9, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Thomas Jon SEIDERS, Bowei WANG, Jeannie M. ARRUDA, Jeffrey Roger ROPPE, Timothy PARR
  • Publication number: 20100298343
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: September 12, 2008
    Publication date: November 25, 2010
    Inventors: John Howard Hutchinson, Thomas Jon Seiders, Jeannie M. Arruda, Nicholas Simon Stock, Jeffrey Roger Roppe, Bowei Wang
  • Publication number: 20100298368
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds that modulate the PGD2 activated chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2). Also described herein are methods of using such CRTH2 modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2 mediated conditions or diseases.
    Type: Application
    Filed: October 31, 2008
    Publication date: November 25, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: Brian Andrew Stearns, John Howard Hutchinson
  • Patent number: 7834037
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Grant
    Filed: October 27, 2007
    Date of Patent: November 16, 2010
    Assignee: Amira Pharmaceuticals, Inc.
    Inventors: John Howard Hutchinson, Nicholas Simon Stock, Jeffrey Roger Roppe
  • Publication number: 20100280049
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds that antagonize the PGD2 activated chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2). Also described herein are methods of using such CRTH2 antagonists, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2 mediated conditions or diseases.
    Type: Application
    Filed: October 31, 2008
    Publication date: November 4, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: Brian Andrew Stearns, Yen Pham Truong, John Howard Hutchinson
  • Patent number: 7795274
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: September 14, 2010
    Assignee: Amira Pharmaceuticals Inc.
    Inventors: John Howard Hutchinson, Nicholas Simon Stock
  • Publication number: 20100173313
    Abstract: Methods for the detection of DP2 receptors in biological samples is disclosed. The induction and detection of DP2 receptors expressed on activated human neutrophils is presented. Also presented are diagnostic kits for the detection of DP2 receptors in biological samples.
    Type: Application
    Filed: January 8, 2010
    Publication date: July 8, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: Gretchen BAIN, John Howard HUTCHINSON, Brian Andrew STEARNS, Kevin Murray SCHAAB, Jillian F. EVANS
  • Publication number: 20100152257
    Abstract: Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
    Type: Application
    Filed: December 15, 2009
    Publication date: June 17, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Thomas Jon SEIDERS, Bowei WANG, Jeannie M. ARRUDA, Jeffrey Roger ROPPE, Timothy PARR
  • Publication number: 20100113503
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: November 5, 2009
    Publication date: May 6, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Brian Andrew Stearns, Jill Melissa Scott
  • Publication number: 20100081673
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: September 28, 2009
    Publication date: April 1, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Nicholas Simon STOCK, Jeffrey Roger ROPPE, Jill Melissa SCOTT, Brian Andrew STEARNS, Yen Pham TRUONG, Deborah VOLKOTS, Timothy PARR
  • Publication number: 20100075934
    Abstract: Described herein are methods for the synthesis of 3-[5-(pyridin-2-ylmethoxy)-3-(2-methyl-2-propylthio)-1-[4-(2-methoxypyridin-5-yl)benzyl]-indol-2-yl]-2,2-dimethyl-propionic acid, pharmaceutically acceptable salts, pharmaceutically acceptable solvates thereof. Also described are pharmaceutical compositions suitable for oral administration to a mammal that include, as well as methods of using such oral pharmaceutical compositions for treating respiratory conditions or diseases, as well as other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: October 24, 2008
    Publication date: March 25, 2010
    Applicant: Amira Pharmaceuticals, Inc.
    Inventors: Melissa Virginia REWOLINSKI, Kevin Murray SCHAAB, Christopher David KING, Jillian F. EVANS, Petpiboon Peppi PRASIT, John Howard HUTCHINSON, Nicholas Simon STOCK
  • Publication number: 20100004331
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: July 2, 2009
    Publication date: January 7, 2010
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Thomas Jon SEIDERS, Bowei WANG, Jeannie M. ARRUDA, Brian Andrew STEARNS
  • Publication number: 20090197959
    Abstract: Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
    Type: Application
    Filed: January 29, 2009
    Publication date: August 6, 2009
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Brian Andrew STEARNS, Jill Melissa SCOTT, Yen Pham TRUONG, Jeffrey Roger ROPPE, Nicholas Simon STOCK, Jeannie M. ARRUDA, Thomas Jon SEIDERS, Bowei WANG
  • Publication number: 20090018170
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which modulate the activity of 5-lipoxygenase-activating protein (FLAP). Also described herein are methods of using such FLAP modulators, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions or diseases.
    Type: Application
    Filed: October 27, 2007
    Publication date: January 15, 2009
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard HUTCHINSON, Nicholas Simon STOCK, Jeffrey Roger ROPPE
  • Publication number: 20070173508
    Abstract: Described herein are compounds and pharmaceutical compositions containing such compounds, which inhibit the activity of 5-lipoxygenase (5-LO). Also described herein are methods of using such 5-LO inhibitors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other leukotriene-dependent or leukotriene mediated conditions, diseases, or disorders.
    Type: Application
    Filed: January 23, 2007
    Publication date: July 26, 2007
    Applicant: AMIRA PHARMACEUTICALS, INC.
    Inventors: John Howard Hutchinson, Thomas Jonathan Seiders, Brian Andrew Stearns, Bowei Wang, Jill Melissa Scott, Yen Pham Truong