Abstract: A system for rapid detection of metabolic deviations of a biological sample including at least one control chamber having spaced electrodes for receiving a biological sample, at least one target chamber having spaced electrodes for receiving the biological sample and a biological reagent, and a measuring and detection device responsive to the control chamber and the target chamber for measuring, at a first time, first impedances of the biological sample in the control chamber and the biological reagent and the biological sample in the target chamber and, at a second time, measuring second impedances of the biological sample in the control chamber and the biological sample and the biological reagent in the target chamber and comparing the second impedances to the first impedances to measure the effect of the biological reagent inducing metabolic deviations to the biological sample in the target chamber and determine whether the biological sample is sensitive to the biological reagent.