Patents by Inventor John Howe

John Howe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090259665
    Abstract: A data processing apparatus, comprising a metadata store storing information about files that are stored in a distributed data storage system, and comprising a class database; one or more processing units; logic configured for receiving and storing in the class database a definition of a class of data storage servers comprising one or more subclasses each comprising one or more server selection criteria; associating the class with one or more directories of the data storage system; in response to a data client storing a data file in a directory, binding the class to the data file, determining and storing a set of identifiers of one or more data storage servers in the system that match the server selection criteria, and providing the set of identifiers to the data client.
    Type: Application
    Filed: April 9, 2008
    Publication date: October 15, 2009
    Inventors: John Howe, Alexander Mitaru, Charles Morris, Don Harschadath Wanigasekara-Mohotti
  • Publication number: 20080096943
    Abstract: Compounds of formula I in free or salt form, wherein T, X, R1, R2, Ra, R3, R4, R5 and U have the meanings as indicated in the specification, are useful for treating a condition mediated by CCR-3, particularly an inflammatory or allergic condition such as an inflammatory or obstructive airways disease. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
    Type: Application
    Filed: August 9, 2005
    Publication date: April 24, 2008
    Inventors: Gurdip Bhalay, Andrew Dunstan, Angela Glen, Trevor John Howe, Clive McCarthy
  • Publication number: 20070226224
    Abstract: The data storage system has metadata server machines, content server machines arranged in groups where each group has a respective one or more of the content server machines, and a system interconnect to which the metadata and content server machines are communicatively coupled. A distributed file system is to be executed in the metadata server machines, the content server machines, and the client machine, to hide complexity of the system from a number of client machine users. The content server machines store slices of the files at locations indicated by the metadata. Other embodiments are also described and claimed.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 27, 2007
    Inventors: Don Wanigasekara-Mohotti, Donald Craig, Alexandru Mitaru, Christopher Davis, John Howe
  • Publication number: 20070214183
    Abstract: Quantitative data about storage load and usage from storage elements of a data storage system are collected. The storage elements are ranked according to the collected quantitative data. A partition across the storage elements in which to store a user requested file is determined. Members of the partition are identified as being one or more of the storage elements. The members are selected from the ranking. The ranking is updated in response to the ranking having aged or the system having been repaired or upgraded. Other embodiments are also described and claimed.
    Type: Application
    Filed: March 8, 2006
    Publication date: September 13, 2007
    Inventors: John Howe, Pralay Dakua
  • Publication number: 20060270041
    Abstract: The present invention provides cell lines for the production of E1-deleted adenovirus (rAd) vectors that complement E1A and E1B functions. The present invention also provides cell lines for the production of E1- and E2-deleted adenovirus vectors that complement E1A, E1B and E2B polymerase functions. The invention provides particular cell lines that complement E1A function by insertion of an E1A sequence containing mutations in the 243R and 289R proteins and an E1B sequence comprising the E1B-55K gene. Production yields in the resulting producer cell lines, designated SL0003 and SL0006, were similar to those obtained from 293 cells without generation of detectable recombinant replication competent adenovirus (“RCA”).
    Type: Application
    Filed: December 12, 2005
    Publication date: November 30, 2006
    Inventors: John Howe, Ken Wills, Robert Ralston, Scott Sherrill
  • Publication number: 20060229389
    Abstract: Extended life slurry seal compositions with controllable mixing times are prepared by incorporating into a conventional water-asphalt emulsion-aggregate rock system, a slurry life-extending mixture of (i) a polycarboxylate compound aqueous solution, (ii) a polyhydroxy phenolic compound aqueous solution, wherein the phenolic compound is preferably a tannin, tannin derivative, lignin, or lignin derivative, and (iii) a non-aqueous diluent to prevent destabilizing interaction between the polycarboxylate and the polyhydroxy phenolic compound aqueous solution. The polyhydroxy phenolic compound in the aqueous solution may be natural or derived synthetically.
    Type: Application
    Filed: April 8, 2005
    Publication date: October 12, 2006
    Inventors: John Howe, Clinton Hairston, H. Hall, Frederick Koerwitz
  • Publication number: 20050160077
    Abstract: A method generally includes electronically receiving an order for a liquid coating over a computer network. The order includes a plurality of inputs relating to a delivery address and a customer-specified color and quantity of liquid coating. The method also includes controllably manufacturing in-a single batch and containerizing the customer-specified color and quantity of liquid coating in accordance with the plurality of inputs. The method further includes causing delivery of the customer-specified color and quantity of containerized liquid coating to the delivery address in accordance with the plurality of inputs.
    Type: Application
    Filed: March 16, 2005
    Publication date: July 21, 2005
    Inventor: John Howes
  • Publication number: 20040087621
    Abstract: Compounds of formula (I) in free or salt form, where Ar1 is phenyl substituted by one or more substituents selected from halogen, cyano, nitro, and C1-C8-alkyl optionally substituted by cyano or halogen, Ar2 is phenyl optionally which is unsubstituted or substituted by one or more substituents selected from halogen, cyano, hydroxy, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy or C1-C8-alkoxycarbonyl, R1 is C1-C8-alkyl substituted by hydroxy, C1-C8-alkoxy, acyloxy, —N(R2)R3, halogen, carboxy, C1-C8-alkoxycarbonyl, phenyl-C1-C8-alkoxycarbonyl, -CON(R4)R5 or by a monovalent cyclic organic group, R2 and R?3 are each independently hydrogen or C1-C8-alkyl, or R2 is hydrogen and R3 is acyl or SO2R6, or R2 and R3 together with the nitrogen atom to which they are attached denote a 5- or 6-membered heterocyclic group, R4 and R5 are each independently hydrogen, C1-C8-alkyl optionally substituted by hydroxy or phenyl, or phenyl optionally substituted by C1-C8-alkyl, halogen, cyano or C1-C8-alkoxy, or R4
    Type: Application
    Filed: April 8, 2003
    Publication date: May 6, 2004
    Inventors: Gurdip Bhalay, Trevor John Howe, Darren Mark Le Grand
  • Patent number: 6670379
    Abstract: Compounds of formula (I) in free or salt form, where Ar1 is phenyl substituted by one or more halogen atoms, Ar2 is phenyl or naphthyl which is unsubstituted or substituted by one or more substituents selected from halogen, cyano, hydroxy, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy or C1-C8-alkoxycarbonyl, R1 is hydrogen or C1-C8-alkyl optionally substituted by hydroxy, C1-C8-alkoxy, acyloxy, N(R2)R3, halogen, carboxy, C1-C8-alkoxycarbonyl, —CON(R4)R5 or by a monovalent cyclic organic group, R2 and R3 are each independently hydrogen or C1-C8-alkyl, or R2 is hydrogen and R3 is acyl or —SO2R6, or R2 and R3 together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R4 and R5 are each independently hydrogen or C1-C8-alkyl, or R4 and R5 together with the nitrogen atom to which they are attached denote a 5 or 6-membered heterocyclic group, R6 is C1-C8-alkyl, C1-C8-haloalkyl, or phenyl optionally substituted by C1-C8-alkyl, and n is 1,
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: December 30, 2003
    Assignee: Novartis AG
    Inventors: Trevor John Howe, Gurdip Bhalay, Darren Mark Le Grand, Thomas Storz
  • Publication number: 20030176460
    Abstract: Compounds of formula (I) in free or salt form, where Ar1 is phenyl substituted by one or more halogen atoms, Ar2 is phenyl or naphthyl which is unsubstituted or substituted by one or more substituents selected from halogen, cyano, hydroxy, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkoxy or C1-C8-alkoxycarbonyl, R1 is hydrogen or C1-C8-alkyl optionally substituted by hydroxy, C1-C8-alkoxy, acyloxy, N(R2)R3, halogen, carboxy, C1-C8-alkoxycarbonyl, —CON(R4)R5 or by a monovalent cyclic organic group, R2 and R3 are each independently hydrogen or C1-C8-alkyl, or R2 is hydrogen and R3 is acyl or —SO2R4 and R5 are each independently with the nitrogen atom to which they are attached denote a 5- or 6-membered heterocyclic group, R4 and R5 are each independently hydrogen or C1-C8-alkyl, or R4 and R5 together with the nitrogen atom to which they are attached denote a 5-6-membered heterocyclic group, R6 is C1-C8-alkyl, C1-C8-haloalkyl, or phenyl optionally substituted by C1-C8-alkyl, and n is 1, 2, 3, or 4,
    Type: Application
    Filed: April 17, 2003
    Publication date: September 18, 2003
    Inventors: Trevor John Howe, Gurdip Bhalay, Darren Mark Le Grand, Thomas Storz
  • Patent number: 5380991
    Abstract: A system and method of allowing a shopper to obtain the benefit of reduced prices for certain items without the necessity of redeeming paper coupons is described, The system employs an integrated circuit (IC) smart card containing an erasable memory therein. This memory would contain information relating to a discount coupon amount, as well as information relating to particular products which have been purchased. This card would be inserted into a reader/writer terminal provided at a retailer's checkout counter. Items which are purchased are scanned and compared with items to be discounted as well as the information provided by the customer IC smart card. After the cashier has totaled the customer's purchases, the information contained in the IC smart card would be altered accordingly.
    Type: Grant
    Filed: November 16, 1993
    Date of Patent: January 10, 1995
    Inventors: Luis Valencia, John Howe