Patents by Inventor John Hutton

John Hutton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10024854
    Abstract: The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells. Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam. In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: July 17, 2018
    Assignees: THE CLEVELAND CLINIC FOUNDATION, THE REGENT OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE
    Inventors: Jan Jensen, John Hutton, Xiaoling Qu, Howard Davidson
  • Publication number: 20170254807
    Abstract: The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells. Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam. In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes.
    Type: Application
    Filed: March 13, 2017
    Publication date: September 7, 2017
    Inventors: Jan Jensen, John Hutton, Xiaoling Qu, Howard Davidson
  • Patent number: 9227861
    Abstract: A dredging system agitates the bottom sediment of a waterway to remove particles and oxygenate the water. The system diffuses air through a grid mounted on a waterway floor, raising particle clouds. The particle clouds are transported downstream by water currents while releasing dissolved oxygen throughout the water column. The method of particle removal and oxygenation is used in shallow depths, less than thirty-three feet (2 bars) with minimum favorable water currents of one-half to one knot. The grid is used for diffusion of air to alleviate hypoxic environments in depths less than sixty-six feet (5 bars).
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: January 5, 2016
    Inventor: John Hutton
  • Publication number: 20150118158
    Abstract: The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells. Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam. In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes.
    Type: Application
    Filed: December 22, 2014
    Publication date: April 30, 2015
    Inventors: Jan Jensen, John Hutton, Xiaoling Qu, Howard Davidson
  • Publication number: 20140326679
    Abstract: The present invention diffuses air through a sea floor-mounted grid, raises particle clouds in four to twenty percent solutions to a height of one to four feet, and transports the particle cloud by favorable currents to designated locations upstream and downstream while releasing dissolved oxygen throughout the water column. The process is used in shallow depths, less that thirty-three feet (2 bars) with minimum favorable water currents of one-half to one knot. The sea floor-mounted grid is used for diffusion of air to alleviate hypoxic environments in depths less than sixty-six feet (5 bars.
    Type: Application
    Filed: May 6, 2013
    Publication date: November 6, 2014
    Inventor: John Hutton
  • Publication number: 20120070847
    Abstract: The invention is based, in part, on the discovery that a polypeptide, referred to herein as Betacam, is selectively expressed on the surface of pancreatic islet cells, Thus, in one aspect, the invention is directed to compositions comprising Betacam or that can be used to detect Betacam. In another aspect, the invention provides methods of detecting (e.g., non-invasively) pancreatic beta cells from a mammalian cell source. Another aspect of the invention is directed to cellular purification of pancreatic beta cells from a heterogeneous cell source of multiple kinds. In another aspect, the invention provides methods of identifying agents that modulate activity of Betacam-In yet another aspect, the invention provides for improved treatment and diagnosis of diabetes.
    Type: Application
    Filed: November 5, 2009
    Publication date: March 22, 2012
    Inventors: Jan Jensen, John Hutton, Xiaoling Qu, Howard Davidson
  • Publication number: 20080161427
    Abstract: A transportable GTL processing facility constructed on an inland barge is provided. Also provided is a process for producing liquid hydrocarbons from natural gas utilizing a transportable GTL processing facility. The facility and process may be used to access and convert stranded natural gas in an economical fashion into liquid hydrocarbons. Further provided is a transportable GTL processing facility and process for producing liquid hydrocarbons wherein the liquid hydrocarbons are upgraded into transportation fuels and other locally usable materials. Water facilities of the transportable GTL processing facility are supplied from the sea near the barge.
    Type: Application
    Filed: September 14, 2007
    Publication date: July 3, 2008
    Applicant: SYNTROLEUM CORPORATION
    Inventors: Kenneth Agee, Juan Inga, John Hutton, Ed Sheehan, Ad van Loenhout, Linda Zeelenberg, Arjan Gerritse, Peter van Sloten
  • Publication number: 20070203059
    Abstract: A method and compositions for detecting autoimmunity to islet glucose-6 phosphatase related protein (IGRP). Detection of IGRP autoantibodies alone, and in combination with other molecules such as the 65-kDa form of glutamate decarboxylase (GAD65), insulin and insulin granule membrane proteins ICA512 (IA-2) and phogrin (IA-2) auto-antigens, provides an effective and reliable chemical assay for the diagnosis of autoimmune (type 1) diabetes. Additionally, this invention provides therapeutic regimens based on IGRP and related molecules for the amelioration of the diabetic clinical condition. Therefore, IGRP alone or in combination with other autoimmune diabetes associated antigens such as insulin, IA-2 and GAD65, is useful in the prediction (diagnosis), treatment (therapy), and prevention (prophylaxis) of diabetes.
    Type: Application
    Filed: September 20, 2004
    Publication date: August 30, 2007
    Inventors: John Hutton, Richard O'Brien, Howard Davidson, Seija Hackl
  • Publication number: 20070021513
    Abstract: A transportable GTL processing facility constructed on an inland barge is provided. Also provided is a process for producing liquid hydrocarbons from natural gas utilizing a transportable GTL processing facility. The facility and process may be used to access and convert stranded natural gas in an economical fashion into liquid hydrocarbons. Further provided is a transportable GTL processing facility and process for producing liquid hydrocarbons wherein the liquid hydrocarbons are upgraded into transportation fuels and other locally usable materials. Water facilities of the transportable GTL processing facility are supplied from the sea near the barge.
    Type: Application
    Filed: February 14, 2006
    Publication date: January 25, 2007
    Inventors: Kenneth Agee, Juan Inga, John Hutton, Ed Sheehan, Ad van Loenhout, Linda Zeelenberg, Arjan Gerritse, Peter van Sloten
  • Patent number: D501732
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: February 15, 2005
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D465662
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: November 19, 2002
    Inventor: John Hutton
  • Patent number: D466312
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: December 3, 2002
    Inventor: John Hutton
  • Patent number: D466313
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: December 3, 2002
    Inventor: John Hutton
  • Patent number: D473060
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: April 15, 2003
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D473388
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: April 22, 2003
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D474347
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: May 13, 2003
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D487988
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: April 6, 2004
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D489912
    Type: Grant
    Filed: July 22, 2003
    Date of Patent: May 18, 2004
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D490995
    Type: Grant
    Filed: September 22, 2003
    Date of Patent: June 8, 2004
    Assignee: Sutherland
    Inventor: John Hutton
  • Patent number: D597323
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: August 4, 2009
    Assignee: David Sutherland, Inc.
    Inventors: Brenda Hutton, legal representative, John Hutton