Patents by Inventor John Hynes

John Hynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10544133
    Abstract: Compounds having the following formula: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: January 28, 2020
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rajeev S. Bhide, John V. Duncia, John Hynes, Satheesh Kesavan Nair, William J. Pitts, Sreekantha Ratna Kumar, Daniel S. Gardner, Natesan Murugesan, Venkatram Reddy Paidi, Joseph B. Santella, Ramesh Kumar Sistla, Hong Wu
  • Publication number: 20190377478
    Abstract: An icon receptacle is disposed along a depth aspect, and one or more icons are disposed within the icon receptacle, one of which is a stack item.
    Type: Application
    Filed: August 24, 2019
    Publication date: December 12, 2019
    Inventors: Imran A. Chaudri, John O. Louch, Christopher Hynes, Timothy Wayne Bumgarner, Eric Steven Peyton
  • Patent number: 10502241
    Abstract: A linear actuator is disclosed. The linear actuator comprises a cylinder portion and a base portion. The cylinder portion comprises a housing defining internally a compression chamber for containing a fluid and comprising a piston assembly that can reciprocate within the compression chamber. The housing further defines a cylinder port in fluid communication with said compression chamber. The base portion defines a first base port and a second base port and a passage extending therebetween fluidly communicating the first base port with the second base port, and comprises valve means operable to control the flow of fluid through the second base port, in which the valve means is actuatable between an open condition in which the flow of fluid through the second base port is permitted, and a closed condition in which the flow of fluid through the second base port is substantially prevented.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: December 10, 2019
    Assignee: Metrol Springs Limited
    Inventors: Christopher John Pegram, Paul Terence Hynes
  • Patent number: 10503342
    Abstract: A user interface can have one or more spaces presented therein. A space is a grouping of one or more program windows in relation to windows of other application programs, such that the program(s) of only a single space is visible when the space is active. A view can be generated of all spaces and their contents.
    Type: Grant
    Filed: August 4, 2006
    Date of Patent: December 10, 2019
    Assignee: APPLE INC.
    Inventors: Assana Fard, John O. Louch, Ralph Brunner, Haroon Sheikh, Eric Peyton, Christopher Hynes
  • Publication number: 20190300038
    Abstract: A trolley for medical equipment includes a base mounted on a plurality of wheels. A brake device including at least one deformable brake pad is located beneath the trolley base. A release mechanism is provided to move the brake pad between a raised position in which it is spaced above a floor surface on which the trolley wheels rest, and a lowered position in which the brake pad is pressed against the floor surface under the weight of the brake device to a exert a braking force on the trolley.
    Type: Application
    Filed: March 18, 2019
    Publication date: October 3, 2019
    Applicant: Keymed (Medical & Industrial Equipment) Ltd.
    Inventor: John Hynes
  • Publication number: 20190292191
    Abstract: Disclosed are compounds of Formula (I) Formula (I) or salts thereof, wherein HET is a heteroaryl selected from oxazolyl, pyrazolyl, imidazo[1,2-b]pyridazin-3-yl, and pyrazolo[1,5-a]pyrimidin-3-yl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a carbon ring atom in the heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; and R1, R3, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
    Type: Application
    Filed: June 23, 2016
    Publication date: September 26, 2019
    Inventors: John V. Duncia, Daniel S. Gardner, John Hynes, John E. Macor, Natesan Murugesan, Joseph B. Santella, Hong Wu, Durgarao Kantheti, Satheesh Kesavan Nair, Venkatram Reddy Paidi, Sreekantha Ratna Kumar, Kandhasamy Sarkunam, Ramesh Kumar Sistla, Subba Rao Polimera
  • Publication number: 20190225005
    Abstract: An article includes a substrate and a graphical component forming an image and an optical component which includes magnetic pigment flakes aligned so as to form a frame pattern which surrounds the image. When light is incident upon the pigment flakes from a light source, light reflected from the frame pattern forms a dynamic frame which surrounds the image and appears to move as the substrate is tilted with respect to the light source. The image appears to be stationary when the dynamic frame appears to move.
    Type: Application
    Filed: April 1, 2019
    Publication date: July 25, 2019
    Applicant: VIAVI SOLUTIONS INC.
    Inventors: Vladimir P. RAKSHA, John Hynes, Laurence Holden, Paul G. Coombs
  • Patent number: 10331287
    Abstract: A user interface can have one or more spaces presented therein. A space is a grouping of one or more program windows in relation to windows of other application programs, such that the program(s) of only a single space is visible when the space is active. A view can be generated of all spaces and their contents.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: June 25, 2019
    Assignee: Apple Inc.
    Inventors: Assana Fard, John O. Louch, Ralph Brunner, Haroon Sheikh, Eric Steven Peyton, Christopher Hynes
  • Publication number: 20190169478
    Abstract: Dual-cure compositions for use in high temperature adhesive applications, and particularly for temporarily adhesively attaching one substrate to another substrate, are provided. These dual-cure adhesives are silicone-based compositions that can be B-staged by exposure UV radiation to provide initial green strength, followed by a C-stage cure to give adhesives that can survive high temperature processes above 200° C., especially above 300° C., yet easy to debond afterwards to allow separation of the top and bottom substrates.
    Type: Application
    Filed: June 5, 2018
    Publication date: June 6, 2019
    Inventors: Shengqian KONG, Yayun LIU, Wenhua ZHANG, Stephen HYNES, John G. WOODS, Jiangbo OUYANG, Chunyu SUN, Bahram ISSARI
  • Patent number: 10294229
    Abstract: Disclosed are compounds of Formula (I) or salts thereof, wherein HET is a heteroaryl selected from pyrrolo[2,3-b]pyridinyl, pyrrolo[2,3 d]pyrimidinyl, pyrazolo[3,4 b]pyridinyl, pyrazolo[3,4 d]pyrimidinyl, imidazolo[4,5 b]pyridinyl, and imidazolo[4,5 d]pyrimidinyl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a nitrogen ring atom in said heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; A is pyrazolyl, imidazolyl, triazolyl, isoxazolyl, oxadiazolyl or dihydroisoxazolyl, each substituted with zero or 1 Ra; and R3, Ra, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: May 21, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Daniel S. Gardner, Joseph B. Santella, Venkatram Reddy Paidi, Hong Wu, John V. Duncia, Satheesh Kesavan Nair, John Hynes, Xiao Zhu
  • Publication number: 20190126658
    Abstract: In a printed article, pigment flakes are magnetically aligned so as to form curved patterns in a plurality of cross-sections normal a continuous imaginary line, wherein radii of the curved patterns increase along the imaginary line from the first point to the second point. When light is incident upon the aligned pigment flakes from a light source, light reflected from the aligned pattern forms a bright image which appears to gradually change its shape and move from one side of the continuous imaginary line to another side of the continuous imaginary line when the substrate is tilted with respect to the light source.
    Type: Application
    Filed: December 18, 2018
    Publication date: May 2, 2019
    Applicant: VIAVI SOLUTIONS INC.
    Inventors: Vladimir P. RAKSHA, John Hynes, Laurence Holden, Paul G. Coombs
  • Patent number: 10259254
    Abstract: An article includes a substrate and a graphical component forming an image and an optical component which includes magnetic pigment flakes aligned so as to form a frame pattern which surrounds the image. When light is incident upon the pigment flakes from a light source, light reflected from the frame pattern forms a dynamic frame which surrounds the image and appears to move as the substrate is tilted with respect to the light source. The image appears to be stationary when the dynamic frame appears to move.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: April 16, 2019
    Assignee: VIAVI SOLUTIONS INC.
    Inventors: Vladimir P. Raksha, John Hynes, Laurence Holden, Paul G. Coombs
  • Patent number: 10232660
    Abstract: In a printed article, pigment flakes are magnetically aligned so as to form curved patterns in a plurality of cross-sections normal a continuous imaginary line, wherein radii of the curved patterns increase along the imaginary line from the first point to the second point. When light is incident upon the aligned pigment flakes from a light source, light reflected from the aligned pattern forms a bright image which appears to gradually change its shape and move from one side of the continuous imaginary line to another side of the continuous imaginary line when the substrate is tilted with respect to the light source.
    Type: Grant
    Filed: July 13, 2015
    Date of Patent: March 19, 2019
    Assignee: VIAVI SOLUTIONS INC.
    Inventors: Vladimir P. Raksha, John Hynes, Laurence Holden, Paul G. Coombs
  • Patent number: 10227340
    Abstract: Compounds having the following formula: or an enantiomer, diastereomer or a pharmaceutically-acceptable salt thereof, wherein X is N or C—R7, are useful as kinase modulators, including IRAK-4 modulation.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: March 12, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Venkatram Reddy Paidi, Sreekantha Ratna Kumar, Abhisek Banerjee, Ramesh Kumar Sistla, Satheesh Kesavan Nair, William J. Pitts, John Hynes
  • Patent number: 10202390
    Abstract: Disclosed are compounds of Formula (I) or salts thereof, wherein: HET is a heteroaryl selected from imidazo[1,2-b]pyridazinyl and pyrazolo[1,5-a]pyrimidinyl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a carbon ring atom in the heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; A is pyrazolyl, imidazolyl, or triazolyl, each substituted with zero or 1 Ra; and R3, Ra, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: February 12, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: John V. Duncia, Daniel S. Gardner, John Hynes, John E. Macor, Satheesh Kesavan Nair, Venkatram Reddy Paidi, Joseph B. Santella, Kandhasamy Sarkunam, Ramesh Kumar Sistla, Subba Rao Polimera, Hong Wu
  • Publication number: 20180370956
    Abstract: Compounds having the following formula: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
    Type: Application
    Filed: June 15, 2018
    Publication date: December 27, 2018
    Inventors: Rajeev S. BHIDE, John V. Duncia, John Hynes, Satheesh K. Nair, William J. Pitts, Sreekantha Ratna Kumar, Daniel S. Gardner, Natesan Murugesan, Venkatram Reddy Paidi, Joseph B. Santella, Ramesh Kumar Sistla, Hong Wu
  • Patent number: 10023562
    Abstract: Compounds having the following formula: or a stereoisomer or a pharmaceutically-acceptable salt thereof, wherein R2 is a monocyclic heteroaryl group, and R1, R3, R4, R5 and R6 are as defined herein, are useful as kinase modulators, including IRAK-4 inhibition.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: July 17, 2018
    Assignee: Bristol-Myers Squibb Company
    Inventors: Rajeev S. Bhide, John V. Duncia, John Hynes, Satheesh K. Nair, William J. Pitts, Sreekantha R. Kumar, Daniel S. Gardner, Natesan Murugesan, Venkatram Reddy Paidi, Joseph B. Santella, Ramesh Sistla, Hong Wu
  • Publication number: 20180186799
    Abstract: Disclosed are compounds of Formula (I) or salts thereof, wherein HET is a heteroaryl selected from pyrrolo[2,3-b]pyridinyl, pyrrolo[2,3 d]pyrimidinyl, pyrazolo[3,4 b]pyridinyl, pyrazolo[3,4 d]pyrimidinyl, imidazolo[4,5 b]pyridinyl, and imidazolo[4,5 d]pyrimidinyl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a nitrogen ring atom in said heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; A is pyrazolyl, imidazolyl, triazolyl, isoxazolyl, oxadiazolyl or dihydroisoxazolyl, each substituted with zero or 1 Ra; and R3, Ra, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
    Type: Application
    Filed: June 23, 2016
    Publication date: July 5, 2018
    Inventors: Daniel S. GARDNER, Joseph B. Santella, Venkatram Reddy Paidi, Hong Wu, John V. Duncia, Satheesh Kesavan Nair, John Hynes, Xiao Zhu
  • Publication number: 20180179213
    Abstract: Disclosed are compounds of Formula (I) or salts thereof, wherein: HET is a heteroaryl selected from imidazo[1,2-b]pyridazinyl and pyrazolo[1,5-a]pyrimidinyl, wherein said heteroaryl is attached to the pyridinyl group in the compound of Formula (I) by a carbon ring atom in the heteroaryl and wherein said heteroaryl is substituted with zero to 2 Rb; A is pyrazolyl, imidazolyl, or triazolyl, each substituted with zero or 1 Ra; and R3, Ra, and Rb are define herein. Also disclosed are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing inflammatory and autoimmune diseases, or in the treatment of cancer.
    Type: Application
    Filed: June 23, 2016
    Publication date: June 28, 2018
    Inventors: John V. DUNCIA, Daniel S. Gardner, John Hynes, John E. Macor, Satheesh Kesavan Nair, Venkatram Reddy Paidi, Joseph B. Santella, Kandhasamy Sarkunam, Ramesh Kumar Sistla, Subba Rao Polimera, Hong Wu
  • Publication number: 20180110580
    Abstract: A container for carrying a medical instrument such as an endoscope after use and before cleaning, comprises a perimeter wall having a height h and defining an enclosure with a diameter d. The perimeter wall is substantially rigid in the height dimension. A flexible base and a flexible cover are attached to the wall. The wall is compressible to a reduced diameter configuration for storage and expandable to an increased diameter configuration for use. The wall may comprise a series of adjacent panels foldable concertina-style to reduce the diameter.
    Type: Application
    Filed: April 28, 2016
    Publication date: April 26, 2018
    Inventor: John Hynes