Abstract: Novel HICP polypeptides, proteins, and nucleic acid molecules which play a role in cell proliferation and fibrosis are disclosed. In addition to isolated, full-length HICP proteins, the invention further provides isolated HICP fusion proteins, antigenic peptides and anti-HICP antibodies. The invention also provides HICP nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a HICP gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.

Abstract: A leg exerciser is provided allowing exercise while the user is seated or stationary. The leg exerciser includes a base member having at least one longitudinally extending track configured to accommodate a foot pad having a plurality of gliders and/or rollers coupled to the bottom of the foot pad and providing a sufficient coefficient of friction to allow the foot pad to smoothly slide within the track. Various alternative configurations provide foldable construction for ease of travel, mounting devices for securing the leg exerciser to a seat, non-removable foot pads and various configurations to provide for variations in travel and/or effort required for movement of the foot pad.

Abstract: Monoglycerides of the formula: ##STR1## wherein R is an aliphatic hydrocarbyl moiety of 2-10 C, straight chain or branched, saturated or unsaturated, and optionally substituted with one or more substituents which do not interfere with angiogenic activity are capable of stimulating angiogenesis in vivo. These compounds, and their pharmaceutical compositions, are useful in wound healing and other therapeutic applications where stimulation of vascularization is beneficial. Antibodies to these materials have also been prepared and are useful in diagnosis and therapy.