Abstract: Systems and methods for removal of thrombus from a blood vessel in a body of a patient are disclosed herein. The method can include: providing a thrombus extraction device including a proximal self-expanding member formed of a fenestrated structure, a substantially cylindrical portion formed of a net-like filament mesh structure having a proximal end coupled to a distal end of the fenestrated structure; advancing a catheter constraining the thrombus extraction device through a vascular thrombus, deploying the thrombus extraction device by stacking a portion of the net-like filament mesh structure outside of the catheter by distally advancing the self-expanding member until the self-expanding member is beyond a distal end of the catheter; retracting the self-expanding member to unstack the portion of the net-like filament mesh structure and to capture the portion of the thrombus; and withdrawing the thrombus extraction device from the body.

Abstract: Provided herein are methods and compositions for enhancement of tumor immunogenicity and for stimulating anti-tumor immune responses in an animal.

Abstract: First and second ladder sections are each molded of a rigid plastics material, and each ladder section includes parallel spaced elongated leg portions integrally connected by two parallel spaced step portions. The ladder sections are pivotally connected by pins extending through overlapping laterally projecting ears and move between a collapsed position with the ladder sections adjacent and an extended aligned position where the second ladder section is supported by the first ladder section. The leg portions of the second ladder section define longitudinally extending cavities which receive corresponding elongated arms pivotal to generally horizontal positions adapted for seating on a motor vehicle tire. The arms also releasably connect with the leg portions of the first ladder section to position the ladder sections in the form of a short A-shaped step ladder.