Abstract: A computer method for identifying product in a distributor's inventory system that fulfills a product request made via a natural language query. the natural language query is received as a product request including multiple words in sequential order. The words are vectorized into word-vectors that are concatenated and used to generate a query embedding. The query embedding is processed utilizing a trained product category classifier that predicts which product category the requested product belongs. Forward and backward sequence vectors are generated from the sequentially ordered words of the query that are concatenated and processed using a trained model specific to the predicted product category. The sequence vectors represent positional relationships between the words of the natural language query. Thereafter, the system identifies product attribute(s) embodied in the natural language query that each correspond to a predetermined key-characteristic of the category.

Abstract: In one aspect, the invention provides compounds of Formula (I) or (II): (I) or (II) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2a, R2b, R3, R4, Z and G are defined as set forth in the disclosure. The invention also provides compounds of Formulae A and B and pharmaceutically acceptable salts and solvates thereof. Other aspects of the invention include the use of compounds of Formulae I, II, A, and B, and pharmaceutically acceptable salts and solvates thereof for the treatment of disorders responsive to modulation of one or more opioid receptors. In certain embodiments, the Compounds of the Invention are useful for treating pain.

Abstract: In one aspect, the invention provides compounds of Formula (I) or (II): (I) or (II) and pharmaceutically acceptable salts and solvates thereof, wherein R1, R2a, R2b, R3, R4, Z and G are defined as set forth in the disclosure. The invention also provides compounds of Formulae A and B and pharmaceutically acceptable salts and solvates thereof. Other aspects of the invention include the use of compounds of Formulae I, II, A, and B, and pharmaceutically acceptable salts and solvates thereof for the treatment of disorders responsive to modulation of one or more opioid receptors. In certain embodiments, the Compounds of the Invention are useful for treating pain.

Abstract: The present disclosure provides substituted pyridine and pyrimidine compounds of Formula (I): A1-X-A2-Z-R1 (I) and the pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein A, X, A, Z, and R are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.

Abstract: The present disclosure provides substituted pyridine and pyrimidine compounds of Formula (I): A1-X-A2-Z-R1 (I) and the pharmaceutically acceptable salts, solvates and prodrugs thereof, wherein A, X, A, Z, and R are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.

Abstract: A portable, light-weight storage apparatus for storing a video game console that also allows a user to sit comfortably in a couch or chair and play video games in front of a living room television or the like. The apparatus provides an “all-in-one” control center with multiple accessories, including an “arcade style” player pad, storage for the video game console unit, storage for a hand-held controller and video game media, instruction and code booklet storage, a player privacy shield and a drink holder. When not in use the storage unit can be easily transported away from the television area to an out of the way location.