Patents by Inventor John J. Lemasters

John J. Lemasters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescent probe
    Patent number: 9970947
    Abstract: Provided herein is a fluorescent probe compound of formula (I): as well as methods of using said compound.
    Type: Grant
    Filed: March 29, 2017
    Date of Patent: May 15, 2018
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: John J. Lemasters, Andaleb I. Kholmukhamedov, Christopher Lindsey, Craig C. Beeson
  • FLUORESCENT PROBE
    Publication number: 20170285045
    Abstract: Provided herein is a fluorescent probe compound of formula (I): as well as methods of using said compound.
    Type: Application
    Filed: March 29, 2017
    Publication date: October 5, 2017
    Inventors: John J. Lemasters, Andaleb I. Kholmukhamedov, Christopher Lindsey, Craig C. Beeson
  • Device to improve Z-axis resolution in confocal microscopy
    Patent number: 6545789
    Abstract: Disclosed are devices to improve the z-axis of confocal microscopes. The devices consists of opaque baffles placed in front of and behind the detection apertures of the microscope systems. By converting the baffles and detection apertures into light sensitive surfaces in an axial array, images from multiple planes of focus can be collected simultaneously with improved z-axis resolution. Several configurations for baffles and axial arrays are also disclosed for use with micro scopes employing pinhole detection and slit detection.
    Type: Grant
    Filed: April 24, 1998
    Date of Patent: April 8, 2003
    Inventor: John J. Lemasters
  • Rinse solution for organs and tissues
    Patent number: 6080730
    Abstract: Disclosed is a rinse solution for rinsing organs and tissues prior to transplantation. The solution comprises, in one liter of solution: from 2 mM to 50 mM glycine; from 0.12 to 1.2 mM adenosine; monosaccharide, sodium, potassium, calcium and magnesium ions; and water for injection sufficient to make a liter of solution; said solution having a pH of about 6.0 to 7.5 and a concentration of potassium of less than 6 MEQ/L. Methods of making and using the solutions are also disclosed.
    Type: Grant
    Filed: November 22, 1995
    Date of Patent: June 27, 2000
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: John J. Lemasters, Ronald G. Thurman
  • Calcium channel blockers to improve preservation of organs stored for transplantation
    Patent number: 5484789
    Abstract: A composition for storing tissue prior to transplantation is disclosed, wherein the tissue storage composition comprises a calcium channel blocker. Also disclosed is a method of storing tissue, comprising contacting the tissue to be stored with an amount of a calcium channel blocker sufficient to reduce tissue injury during storage under conditions such that viability of the tissue is maintained.
    Type: Grant
    Filed: October 31, 1989
    Date of Patent: January 16, 1996
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Ronald G. Thurman, John J. Lemasters
  • Rinse solution for organs and tissues
    Patent number: 5145771
    Abstract: Disclosed is a rinse for preservation solution for organs and tissues selected for transplantation. The solution can be used at all temperatures from 0.degree. C. to normal body temperature and continues to be protective above 10.degree. C. Methods for preparing organs and tissues preserved in a preservation solution prior to transplant into a recipient are also disclosed.
    Type: Grant
    Filed: October 10, 1990
    Date of Patent: September 8, 1992
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: John J. Lemasters, Ronald G. Thurman