Patents by Inventor John J. Mastrototaro
John J. Mastrototaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7098803Abstract: A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and Tirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.Type: GrantFiled: July 23, 2004Date of Patent: August 29, 2006Assignee: Medtronic MiniMed, Inc.Inventors: Alfred E. Mann, Richard E. Purvis, John J. Mastrototaro, James D. Causey, James Henke, Peter Hong, John H. Livingston, Clifford W. Hague, Brad T. Hite
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Patent number: 7029444Abstract: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression.Type: GrantFiled: August 25, 2004Date of Patent: April 18, 2006Assignee: Medtronic MiniMed, Inc.Inventors: John J. Shin, Kris R. Holtzclaw, Nandita D. Dangui, Sami Kanderian, Jr., John J. Mastrototaro, Peter I. Hong
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Patent number: 7003336Abstract: A sensor and method of making the same for implantation in a body that includes a substrate with notches cut in the substrate to form a necked down region in the substrate; and at least one sensor electrode formed from one or more conductive layers. Preferably, the thickness of the substrate ranges from approximately 25? to 350?, but the thickness of the substrate can range from 5? to 750?. The sensor may be incorporated in to a sensor assembly includes a slotted needle having a slot. The notches creating the necked down region allow the substrate to slide into the slotted needle, which that has the slot narrow enough to permit passage of the necked down region. However, a non-necked down region of the substrate is prevented from pulling out of the slotted needle through the slot. The slot of the slotted needle may also permit the necked down region of the substrate to slide down the slot.Type: GrantFiled: February 8, 2001Date of Patent: February 21, 2006Assignee: Medtronic MiniMed, Inc.Inventors: James D. Holker, Guillermo A. Calle, Kevin D. Branch, John J. Mastrototaro, William P. Van Antwerp, Nannette Van Antwerp
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Patent number: 6895263Abstract: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression.Type: GrantFiled: May 8, 2002Date of Patent: May 17, 2005Assignee: Medtronic MiniMed, Inc.Inventors: John J. Shin, Kris R. Holtzclaw, Nandita D. Dangui, Sami Kanderian, Jr., John J. Mastrototaro, Peter I. Hong
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Patent number: 6892085Abstract: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.Type: GrantFiled: November 26, 2002Date of Patent: May 10, 2005Assignee: Medtronic MiniMed, Inc.Inventors: K. Collin McIvor, James L. Cabernoch, Kevin D. Branch, Nannette M. Van Antwerp, Edgardo C. Halili, John J. Mastrototaro
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Publication number: 20040263354Abstract: A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and Tirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.Type: ApplicationFiled: July 23, 2004Publication date: December 30, 2004Applicant: MINIMED, INC.Inventors: Alfred E. Mann, Richard E. Purvis, John J. Mastrototaro, James D. Causey, James Henke, Peter Hong, John H. Livingston, Clifford W. Hague, Brad T. Hite
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Patent number: 6809653Abstract: A telemetered characteristic monitor system includes a remotely located data receiving device, a sensor for producing signal indicative of a characteristic of a user, and a transmitter device. The transmitter device includes a housing, a sensor connector, a processor, and a transmitter. The transmitter receives the signals from the sensor and wirelessly transmits the processed signals to the remotely located data receiving device. The processor coupled to the sensor processes the signals from the sensor for transmission to the remotely located data receiving device. The data receiving device may be a characteristic monitor, a data receiver that provides data to another device, an RF programmer for a medical device, a medication delivery device (such as an infusion pump), or the like.Type: GrantFiled: December 17, 1999Date of Patent: October 26, 2004Assignee: Medtronic MiniMed, Inc.Inventors: Alfred E. Mann, Richard E. Purvis, John J. Mastrototaro, James D. Causey, James Henke, Peter Hong, John H. Livingston, Clifford W. Hague, Brad T. Hite
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Publication number: 20040143173Abstract: A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing and a resealable insertion site coupled to one end of the site housing. Preferably, the site housing is formed to have an interior cavity, and includes an outer membrane made of a material selected to promote vascularization and having a first pore size, and an inner membrane made of a material selected to be free of tissue ingress. Also, the site housing permits the analyte to pass through the site housing to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site is provided for inserting the replaceable analyte sensor into the interior cavity of the site housing.Type: ApplicationFiled: June 2, 2003Publication date: July 22, 2004Applicant: MEDTRONIC MINIMED, INC.Inventors: Bahar Reghabi, Rajiv Shah, Eunjoo Jin, Rebecca Gottlieb, Michael E. Miller, Nannette M. Van Antwerp, Bradley J. Enegren, William P. Van Antwerp, John J. Mastrototaro
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Publication number: 20040074785Abstract: Embodiments of the invention provide analyte sensors having stabilized coating compositions and methods for making such sensors. Illustrative embodiments include electrochemical glucose sensors having stabilized glucose oxidase coatings that are generated for example, via spin coating processes.Type: ApplicationFiled: October 18, 2002Publication date: April 22, 2004Inventors: James D. Holker, John J. Mastrototaro, Glenn Noronha, Rajiv Shah, Yanan Zhang, Udo Hoss, Kevin D. Branch
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Publication number: 20030220552Abstract: A reusable analyte sensor site for use with a replaceable analyte sensor for determining a level of an analyte includes a site housing material and a resealable insertion site coupled to one end of the site housing material. Preferably, the site housing material is formed to have an interior cavity with an opening. The site housing material is selected to promote tissue ingrowth and vascularization, and yet be free of tissue ingress. Also, the site housing material permits the analyte to pass through the site housing material to the interior cavity to permit measurement by the replaceable analyte sensor. The resealable insertion site provides a for inserting the replaceable analyte sensor into the interior cavity of the site housing material.Type: ApplicationFiled: February 12, 2003Publication date: November 27, 2003Applicant: MEDTRONIC MINIMED, INC.Inventors: Bahar Reghabi, Rajiv Shah, Eunjoo Jin, Rebecca Gottlieb, Michael E. Miller, Nannette M. Van Antwerp, Bradley J. Enegren, William P. Van Antwerp, John J. Mastrototaro
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Patent number: 6558351Abstract: A closed loop infusion system controls the rate that fluid is infused into the body of a user. The closed loop infusion system includes a sensor system, a controller, and a delivery system. The sensor system includes a sensor for monitoring a condition of the user. The sensor produces a sensor signal, which is representative of the condition of the user. The sensor signal is used to generate a controller input. The controller uses the controller input to generate commands to operate the delivery system. The delivery system infuses a liquid into the user at a rate dictated by the commands from the controller. Preferably, the sensor system monitors the glucose concentration in the body of the user, and the liquid infused by the delivery system into the body of the user includes insulin. The sensor system uses the sensor signal to generate a message that is sent to the delivery system. The message includes the information used to generate the controller input.Type: GrantFiled: June 1, 2000Date of Patent: May 6, 2003Assignee: Medtronic MiniMed, Inc.Inventors: Garry M. Steil, Kerstin Rebrin, Paul V. Goode, Jr., John J. Mastrototaro, Richard E. Purvis, William P. Van Antwerp, John J. Shin, Cary D. Talbot
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Publication number: 20030078481Abstract: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.Type: ApplicationFiled: November 26, 2002Publication date: April 24, 2003Applicant: MINIMED INC.Inventors: K. Collin McIvor, James L. Cabernoch, Kevin D. Branch, Nannette M. Van Antwerp, Edgardo C. Halili, John J. Mastrototaro
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Publication number: 20030069383Abstract: Methods for reducing the electrode impedance of implantable biosensors by coating the surface of the biosensor with a uniform hydrogel which allows unimpeded water movement around the sensor are provided. The surface coatings are compositions which are biocompatible and are capable of water uptake of at least 120% of their weight, more preferably at least 200% of their weight. Upon the uptake of water, the hydrogels used in the present invention will also swell and provide a layer of water around the electrodes to which the hydrogels are attached. The hydrogels can be prepared from (a) a diisocyanate, (b) a hydrophilic polymer which is a hydrophilic diol, a hydrophilic diamine, or a combination thereof, and optionally, (c) a chain extender.Type: ApplicationFiled: August 6, 2002Publication date: April 10, 2003Inventors: William Peter Van Antwerp, Christian C. Decker, John J. Mastrototaro
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Patent number: 6520326Abstract: A glucose sensor package system that includes a glucose sensor and a protective package that indicates exposure to temperature changes to indicate proper temperature control. Also covered are methods of transporting and sterilizing the package. In addition, glucose sensors directed to various sizing and positioning of the electrodes on the glucose sensor are covered.Type: GrantFiled: October 9, 2001Date of Patent: February 18, 2003Assignee: Medtronic MiniMed, Inc.Inventors: K. Collin McIvor, James L. Cabernoch, Kevin D. Branch, Nannette M. Van Antwerp, Edgardo C. Halili, John J. Mastrototaro
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Patent number: 6484045Abstract: A method of making a sensor includes the steps of providing a preformed self-supporting flexible substrate; sputter-depositing a metal layer on the substrate; etching the sputter-deposited metal layers to form a sensor electrode having a proximal segment and a distal segment; plating a metal layer on the sensor electrode; and separating the sensor electrode and at least a portion of the substrate underlying the sensor electrode from the remainder of the substrate. Sensors prepared according to the inventive methods, and sensor sets including the sensors, are also provided.Type: GrantFiled: February 10, 2000Date of Patent: November 19, 2002Assignee: Medtronic MiniMed, Inc.Inventors: James D. Holker, Guillermo A. Calle, Kevin D. Branch, John J. Mastrototaro, William P. Van Antwerp
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Publication number: 20020161288Abstract: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression.Type: ApplicationFiled: May 8, 2002Publication date: October 31, 2002Applicant: MEDTRONIC MINIMED, INC.Inventors: John J. Shin, Kris R. Holtzclaw, Nandita D. Dangui, Sami Kanderian, John J. Mastrototaro, Peter I. Hong
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Publication number: 20020137997Abstract: Methods and apparatuses for electrically connecting a medical glucose monitor to a glucose sensor set, as well as for testing the operation of the glucose monitor, monitor cable and glucose sensor set are provided. In one embodiment, an electric cable comprises a cable member, a first connector and a second connector. The cable member in turn comprises at least one insulated conductor, a conductive shielding layer disposed around the at least one insulated conductor; and an insulating layer disposed around the conductive shielding layer. A glucose monitoring system test plug provides for a releasable electrical connection with the electric cable. In one embodiment, the test plug comprises a housing and a fitting affixed thereto which is adapted to electrically couple the test plug with the electric cable.Type: ApplicationFiled: May 22, 2002Publication date: September 26, 2002Applicant: MiniMed Inc.Inventors: John J. Mastrototaro, Richard E. Purvis, Edgardo C. Halili, Eric Johnson
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Patent number: 6424847Abstract: A method of calibrating glucose monitor data includes collecting the glucose monitor data over a period of time at predetermined intervals. It also includes obtaining at least two reference glucose values from a reference source that temporally correspond with the glucose monitor data obtained at the predetermined intervals. Also included is calculating the calibration characteristics using the reference glucose values and the corresponding glucose monitor data to regress the obtained glucose monitor data. And calibrating the obtained glucose monitor data using the calibration characteristics is included. In preferred embodiments, the reference source is a blood glucose meter, and the at least two reference glucose values are obtained from blood tests. In additional embodiments, the calculation of the calibration characteristics is obtained using linear regression and in particular embodiments, least squares linear regression.Type: GrantFiled: February 23, 2000Date of Patent: July 23, 2002Assignee: Medtronic Minimed, Inc.Inventors: John J. Mastrototaro, Todd M. Gross, John J. Shin
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Patent number: 6418332Abstract: Methods and apparatuses for electrically connecting a medical glucose monitor to a glucose sensor set, as well as for testing the operation of the glucose monitor, monitor cable and glucose sensor set are provided. In one embodiment, an electric cable comprises a cable member, a first connector and a second connector. The cable member in turn comprises at least one insulated conductor, a conductive shielding layer disposed around the at least one insulated conductor; and an insulating layer disposed around the conductive shielding layer. A glucose monitoring system test plug provides for a releasable electrical connection with the electric cable. In one embodiment, the test plug comprises a housing and a fitting affixed thereto which is adapted to electrically couple the test plug with the electric cable.Type: GrantFiled: February 24, 2000Date of Patent: July 9, 2002Assignee: MiniMedInventors: John J. Mastrototaro, Richard E. Purvis, Edgardo C. Halili, Eric Johnson
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Patent number: D469540Type: GrantFiled: November 7, 2001Date of Patent: January 28, 2003Assignee: Medtronic MiniMed, Inc.Inventors: James D. Holker, Nannette M. Van Antwerp, John J. Mastrototaro, William P. Van Antwerp