Patents by Inventor John J. Miller
John J. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148429Abstract: A method for determining motional branch current in an ultrasonic transducer of an ultrasonic surgical device over multiple frequencies of a transducer drive signal. The method may comprise, at each of a plurality of frequencies of the transducer drive signal, oversampling a current and voltage of the transducer drive signal, receiving, by a processor, the current and voltage samples, and determining, by the processor, the motional branch current based on the current and voltage samples, a static capacitance of the ultrasonic transducer and the frequency of the transducer drive signal.Type: ApplicationFiled: November 29, 2023Publication date: May 9, 2024Inventors: Eitan T. Wiener, Jeffrey L. Aldridge, Brian T. Noyes, Jeffrey D. Messerly, James R. Giordano, Robert J. Beetel, III, Nathan J. Price, Matthew C. Miller, Jeffrey P. Wiley, Daniel W. Price, Robert L. Koch, JR., Joseph A. Brotz, John E. Hein
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Patent number: 11963691Abstract: A surgical instrument, has an end effector that includes an ultrasonic blade, and a clamp arm that moves relative to the ultrasonic blade from an opened position toward an intermediate position and a closed position. The clamp arm is offset from the ultrasonic blade to define a predetermined gap in the intermediate position between the opened position and the closed position. A clamp arm actuator connects to the clamp arm and moves from an opened configuration to a closed configuration to direct the clamp arm from the opened position toward the intermediate position and the closed position. A spacer connects with the clamp arm to inhibit movement of the clamp arm from the intermediate position toward the closed position for maintaining the predetermined gap between the clamp arm and the ultrasonic blade.Type: GrantFiled: December 21, 2020Date of Patent: April 23, 2024Assignee: Cilag GmbH InternationalInventors: Ryan M. Asher, Brian D. Black, John E. Brady, Joseph Dennis, Geni M. Giannotti, Bryce L. Heitman, Timothy S. Holland, Joseph E. Hollo, Andrew Kolpitcke, Amy M. Krumm, Jason R. Lesko, Matthew C. Miller, David A. Monroe, Ion V. Nicolaescu, Rafael J. Ruiz Ortiz, Matthew S. Schneider, Richard C. Smith, Shawn C. Snyder, Sarah A. Worthington, Monica L. Rivard, Fajian Zhang
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Publication number: 20240115701Abstract: Provided herein are methods of separating host cell lipases from a production protein in chromatographic processes and methods of improving polysorbate-80 stability in a production protein formulation by separating host cell lipases from the production protein using chromatographic processes. Also provided herein are compositions comprising antibodies or antigen binding fragments thereof that bind to cytotoxic T lymphocyte associated antigen 4 (CTLA4). In another aspect, such compositions further comprise a reduced level of host cell proteins and/or increased level of polysorbate-80 (PS-80) stability.Type: ApplicationFiled: September 18, 2020Publication date: April 11, 2024Applicant: Merck Sharp & Dohme Corp.Inventors: Rebecca A. Chmielowski, Francis K. Insaidoo, Justin B. Miller, David J. Roush, Darshini Shah, John P. Welsh
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Patent number: 11938733Abstract: A micro-valve includes an orifice plate having a first surface, a second surface and an orifice extending from the first surface to the second surface. An actuating beam is disposed in spaced relation to the orifice plate. The actuating beam includes a base portion and a cantilevered portion. The base portion is separated from the orifice plate by a predetermined distance. The cantilevered portion extends from the base portion such that an overlapping portion thereof overlaps the orifice. The actuating beam is movable between a closed position and an open position. The micro-valve also includes a sealing structure including a sealing member disposed at the overlapping portion of the cantilevered portion. When the actuating beam is in the closed position, the cantilevered portion is positioned such that the sealing structure seals the orifice so as to close the micro-valve.Type: GrantFiled: October 24, 2022Date of Patent: March 26, 2024Assignee: Matthews International CorporationInventors: William A. Buskirk, Steven E. Flego, Charles C. Haluzak, John Whitlock, Eric R. Miller, Glenn J. T. Leighton
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Patent number: 11911027Abstract: A surgical stapler, or fastening instrument, may generally comprise a layer, such as a tissue thickness compensator, for example, releasably attached to a fastener cartridge and/or anvil by a flowable attachment portion. The flowable attachment portion may be indefinitely flowable. The flowable attachment portion may be flowable from the time that layer is installed to the fastener cartridge to the time in which the layer is implanted to patient tissue. The flowable attachment portion may comprise a pressure sensitive adhesive. The flowable attachment portion may comprise an adhesive laminate comprising a base layer comprising the tissue thickness compensator and an adhesive layer on at least a portion of a surface of the base layer comprising the pressure sensitive adhesive. Articles of manufacture comprising flowable attachment portion and methods of making and using the flowable attachment portion are also described.Type: GrantFiled: November 15, 2019Date of Patent: February 27, 2024Assignee: Cilag GmbH InternationalInventors: Taylor W. Aronhalt, Michael J. Vendely, Lauren S. Weaner, Brandon J. Lloyd, Frederick E. Shelton, IV, Michael J. Miller, Michael T. Isaacs, Emily Ann Schellin, John V. Hunt, John E. Feds
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Publication number: 20230110756Abstract: The present technology is directed to barium-133 (“Ba-133”) based standards that simulate expected energy emissions of iodine-131 (“I-131”), and thus can be used to calibrate radioactivity measuring instruments (e.g., dose calibrators) used to measure the radioactivity of I-131 drug products. The Ba-133 standards can be manufactured in geometries typical of those used to administer I-131 drug products, including, for example, as a capsule, a syringe, a vial, etc.Type: ApplicationFiled: October 7, 2022Publication date: April 13, 2023Inventors: John J. Miller, Daniel J. Kalas
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Publication number: 20230044304Abstract: Topical applications that provide a nitric oxide therapy to a surface are provided. Systems for providing a topical nitric oxide therapy can comprise a nitrite medium in a first container, the nitrite medium comprising about 3% of a nitrite component by weight. The system comprises an acidic medium in a second container, the acidic medium comprising about 9% by weight of one or more acidic reactants. The nitrite medium and the acidic medium are configured to be combined to form a nitric oxide topical medium producing nitric oxide suitable for topical application and suitable for administering nitric oxide therapy wherein a therapeutically effective amount of the nitric oxide topical medium is applied to a treatment surface suitable for receiving nitric oxide therapy, whereby the application of the therapeutically effective amount is adapted to deliver a dose of nitric oxide at the treatment surface of a patient.Type: ApplicationFiled: April 22, 2022Publication date: February 9, 2023Inventors: J.W. Randolph Miller, Ross M. Wille, John J. Miller, Stephen H. Fairbanks
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Publication number: 20230001125Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: ApplicationFiled: April 22, 2022Publication date: January 5, 2023Inventors: J.W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Patent number: 9636247Abstract: An adjustable lordosis orthopedic insert and method of adjusting the lordosis orthopedic insert for an anatomy of a patient has a first support member configured to support a lordosis of a user's spine and a second adjustable member permanently connected to the first support member. The second adjustable member also has a relatively movable other end with a plurality of lordotic position settings to match corresponding first support member lordotic attachment positions to enable the first support member to conform to a desired setting angle. Fasteners extend through the first support member and the second adjustable member to permanently fix one of the plurality of lordotic position settings to configure the first support member at the desired lordosis setting angle. When appropriately adjusted to a setting angle, the lordosis orthopedic insert can be mounted within the flexible padded covering member for fixation to an appropriate back.Type: GrantFiled: September 18, 2014Date of Patent: May 2, 2017Assignee: ORTHOMERICA PRODUCTS, INC.Inventors: John J. Miller, Robert B. Hamilton, III
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Publication number: 20160256841Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: ApplicationFiled: March 10, 2016Publication date: September 8, 2016Inventors: J.W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Patent number: 9302238Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: GrantFiled: March 3, 2014Date of Patent: April 5, 2016Assignee: SYK TECHNOLOGIES, LLCInventors: J. W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Publication number: 20160081841Abstract: An adjustable lordosis orthopedic insert and method of adjusting the lordosis orthopedic insert for an anatomy of a patient has a first support member configured to support a lordosis of a user's spine and a second adjustable member permanently connected to the first support member. The second adjustable member also has a relatively movable other end with a plurality of lordotic position settings to match corresponding first support member lordotic attachment positions to enable the first support member to conform to a desired setting angle. Fasteners extend through the first support member and the second adjustable member to permanently fix one of the plurality of lordotic position settings to configure the first support member at the desired lordosis setting angle. When appropriately adjusted to a setting angle, the lordosis orthopedic insert can be mounted within the flexible padded covering member for fixation to an appropriate back.Type: ApplicationFiled: September 18, 2014Publication date: March 24, 2016Inventors: John J. Miller, Robert B. Hamilton, III
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Publication number: 20140314880Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: ApplicationFiled: March 3, 2014Publication date: October 23, 2014Inventors: J. W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Patent number: 8685467Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: GrantFiled: August 3, 2011Date of Patent: April 1, 2014Inventors: J. W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Publication number: 20130022691Abstract: An apparatus for controlled delivery of nitric oxide. A pump draws air through an activated carbon filter and into a reaction chamber. The generation of nitric oxide occurs in the reaction chamber. A second pump draws the gas in the reaction chamber through a calcium hydroxide filter and delivers the nitric oxide through an orifice, or aperture, that controls the flow of nitric oxide delivered. The nitric oxide is filtered through a calcium hydroxide filter just prior to being made available for various nitric oxide therapies. Topical applications that provide a nitric oxide therapy to a surface are also provided.Type: ApplicationFiled: August 3, 2011Publication date: January 24, 2013Inventors: J.W. Randolph Miller, John J. Miller, Stephen H. Fairbanks
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Patent number: 7762276Abstract: A check valve for a fluid handling system is disclosed, the check valve having a main body with a poppet valve disposed therein and a spring urging the poppet valve into abutment with an inner surface of the main body, wherein the check valve facilitates a flow of fluid in one direction and militates against the flow of fluid in an opposite direction.Type: GrantFiled: June 27, 2006Date of Patent: July 27, 2010Assignee: Superb Industries, Inc.Inventors: John J. Miller, Jr., Michael Hall, Charles Brackney, Andy Keffler
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Patent number: 7439850Abstract: A keyless entry system is disclosed for use in an entry system wherein the latching mechanism may be locked or unlocked by either a key or a remotely controlled mechanism.Type: GrantFiled: April 27, 2006Date of Patent: October 21, 2008Assignee: Superb Industries, Inc.Inventors: Robert Boulard, Jerrit Ekama, Eric Harz, John J. Miller, Jr., Ryan D. Luecke, Charles R. Brackney, III, Daniel J. Miller
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Publication number: 20070240464Abstract: A remote locking system is disclosed, wherein energy for operating a locking and unlocking mechanism is captured and stored for re-use in an energy storage device. The energy stored may be mechanical, hydraulic, electrical, and pneumatic, for example. The remote locking system including an accessory system which is self contained and self powered, wherein the accessory system provides a simple and economical system which can be provided as original equipment or aftermarket equipment, and aesthetics of the vehicle are preserved while a complexity of installation, cost of the accessory system, and cost of installation are minimized.Type: ApplicationFiled: April 18, 2007Publication date: October 18, 2007Inventors: John J. Miller, Charles R. Brackney, Ryan D. Luecke, Daniel J. Miller
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Patent number: 7058439Abstract: A breast prosthesis may be formed by forming an outer layer on a mold, and filling the mold with a polymerizable foaming composition. The mold may be formed by forming a computer model of the prosthesis based on scanning a patient. The computer model may be used to form a solid model. A prosthesis may be coupled to the patient by coupling at least one metallic insert to the prosthesis and at least one magnet to the patient. Alternately, the prosthesis may be formed with a retaining harness integral to the prosthesis. In still another method, the prosthesis may be coupled to a retaining device surgically implanted in the patient.Type: GrantFiled: May 3, 2002Date of Patent: June 6, 2006Assignee: ContourMed, Inc.Inventors: L. Daniel Eaton, John J. Miller, John L. May
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Patent number: D509654Type: GrantFiled: July 19, 2004Date of Patent: September 20, 2005Assignee: Kmart of Michigan, Inc.Inventor: John J. Miller