Patents by Inventor John J. Munro, III
John J. Munro, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11957932Abstract: A brachytherapy source delivery device includes a first tissue-piercing leg having proximal and distal ends, a second tissue-piercing leg having proximal and distal ends, wherein the proximal ends of the first and second tissue-piercing legs are joined at a span section in a first angular orientation with respect to each other, and a carrier element formed at, or attached to, the span section, the carrier element configured to support a radioactive brachytherapy source. The distal ends of the first and second legs can be curved inward toward each other to pierce a tissue when engaged toward each other into a closed position. The first and second tissue-piercing legs can be formed of a wire having a circular cross-sectional or non-circular cross-sectional shape. The carrier element can be tangentially attached to the span section. Each of the legs have a length that is greater than the length of the span section.Type: GrantFiled: December 7, 2021Date of Patent: April 16, 2024Assignee: PointSource Technologies, LLCInventors: David E. Wazer, Thomas A. DiPetrillo, John J. Munro, III
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Patent number: 11224761Abstract: A brachytherapy source delivery device includes a first tissue-piercing leg having proximal and distal ends, a second tissue-piercing leg having proximal and distal ends, wherein the proximal ends of the first and second tissue-piercing legs are joined at a span section in a first angular orientation with respect to each other, and a carrier element formed at, or attached to, the span section, the carrier element configured to support a radioactive brachytherapy source. The distal ends of the first and second legs can be curved inward toward each other to pierce a tissue when engaged toward each other into a closed position. The first and second tissue-piercing legs can be formed of a wire having a circular cross-sectional or non-circular cross-sectional shape. The carrier element can be tangentially attached to the span section. Each of the legs have a length that is greater than the length of the span section.Type: GrantFiled: November 19, 2019Date of Patent: January 18, 2022Assignee: PointSource Technologies, LLCInventors: David E. Wazer, Thomas A. DiPetrillo, John J. Munro, III
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Patent number: 10576299Abstract: The present invention provides a means for achieving greater ability to negotiate small radii like 5 mm of curvature in the human body to treat tumors, for example, with radioactive materials. This is accomplished by incorporating the source capsule into a flexible housing, which, in its simplest configuration, eliminates the direct connection of the source capsule to the driving cable, adding a degree of flexibility that is not available with a direct connection of the source capsule to the driving cable as in the presently available source capsules, and further providing segmented source capsules, and further providing devices for shielding of tissue using the segmented source assemblies.Type: GrantFiled: May 22, 2017Date of Patent: March 3, 2020Inventor: John J Munro, III
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Patent number: 10286227Abstract: Devices and techniques for permanent application of radioactive sources in the field of brachytherapy are described. In an embodiment, an implantable device for radiation therapy of pathological tissues directed toward the administration of radiation to tissue adjacent a cavity wall or surgical excision. The device may include an insertable member, such as a substantially cylindrical member, having at least two ends, a central section positioned between the ends, and a fixation element to retain the implantable device implanted in tissue at a desired position. The device may further include a radioactive source at least partially positioned within the insertable member and that is disposed to deliver radiation to a desired area.Type: GrantFiled: May 15, 2017Date of Patent: May 14, 2019Assignee: Spec Med Intellectual Property, LLCInventors: John J. Munro, III, Matthew R. Hollows
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Publication number: 20170246476Abstract: Devices and techniques for permanent application of radioactive sources in the field of brachytherapy are described. In an embodiment, an implantable device for radiation therapy of pathological tissues directed toward the administration of radiation to tissue adjacent a cavity wall or surgical excision. The device may include an insertable member, such as a substantially cylindrical member, having at least two ends, a central section positioned between the ends, and a fixation element to retain the implantable device implanted in tissue at a desired position. The device may further include a radioactive source at least partially positioned within the insertable member and that is disposed to deliver radiation to a desired area.Type: ApplicationFiled: May 15, 2017Publication date: August 31, 2017Inventors: John J. Munro, III, Matthew R. Hollows
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Patent number: 9682251Abstract: Devices and techniques for permanent application of radioactive sources in the field of brachytherapy are described. In an embodiment, an implantable device for radiation therapy of pathological tissues directed toward the administration of radiation to tissue adjacent a cavity wall or surgical excision. The device may include an insertable member, such as a substantially cylindrical member, having at least two ends, a central section positioned between the ends, and a fixation element to retain the implantable device implanted in tissue at a desired position. The device may further include a radioactive source at least partially positioned within the insertable member and that is disposed to deliver radiation to a desired area.Type: GrantFiled: June 18, 2014Date of Patent: June 20, 2017Assignee: SPEC MED Intellectual Property, LLCInventors: John J. Munro, III, Matthew R. Hollows
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Publication number: 20140378739Abstract: Devices and techniques for permanent application of radioactive sources in the field of brachytherapy are described. In an embodiment, an implantable device for radiation therapy of pathological tissues directed toward the administration of radiation to tissue adjacent a cavity wall or surgical excision. The device may include an insertable member, such as a substantially cylindrical member, having at least two ends, a central section positioned between the ends, and a fixation element to retain the implantable device implanted in tissue at a desired position. The device may further include a radioactive source at least partially positioned within the insertable member and that is disposed to deliver radiation to a desired area.Type: ApplicationFiled: June 18, 2014Publication date: December 25, 2014Inventors: John J. Munro, III, Matthew R. Hollows
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Patent number: 8833631Abstract: A staple delivery applicator for delivering radioactive staples during brachytherapy medical treatment has an actuating device for attaching source staples located distally thereform. The actuating device is removably attachable to an actuator arm on a proximal end. A staple applicator cartridge holder is attached to the actuator arm on a distal end. The staple applicator cartridge is mountable in the holder and has slots for mounting of radioactive source staples therein. An anvil therein crimps the staples. The staple applicator cartridge holder is removably mountable in a connector and the connector is also removably mounted to a surgical staple holder. A trigger device has a control for closing the anvil of the cartridge holder and for firing of the source staples in the cartridge therein to cause the staples to crimp, and a control for opening the anvil and releasing the trigger device from the actuator arm.Type: GrantFiled: May 16, 2011Date of Patent: September 16, 2014Inventors: John J. Munro, III, Kevin Schehr, Krissie K. Zambrano, Matthew Hollows
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Patent number: 8679377Abstract: A gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more nonmetals which upon irradiation do not produce products capable of sustained emission of radiation which would unacceptably interfere with the gamma radiation of 75Selenium. A further gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more metals or nonmetals, the neutron irradiation of which does produce products capable of sustained emission of radiation which would acceptably complement the gamma radiation of 75Selenium. Further, the gamma radiation source may have components that are separately irradiated before being combined and the components may be of natural isotopic composition or of isotopically modified composition so that the subsequent radiation peaks may also be adjusted in relative frequency.Type: GrantFiled: December 5, 2012Date of Patent: March 25, 2014Inventors: John J. Munro, III, Kevin J. Schehr
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Publication number: 20140066687Abstract: A system provided for delivering Accelerated Partial Breast Irradiation (APBI) and for delivering a boost to standard whole-breast irradiation (WBI) for the treatment of breast cancer that significantly reduces the risks of adverse cosmetic outcomes and toxicities. This is achieved by a method and device for delivering a uniform radiation dose to the target volume with significantly reduced dose to the non-target volume, skin and chest wall of the ipsilateral breast, and virtually no dose to the contralateral breast, lungs, and heart.Type: ApplicationFiled: August 29, 2013Publication date: March 6, 2014Applicant: Source Production & Equipment Co., Inc.Inventor: John J. Munro, III
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Publication number: 20130302236Abstract: A gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more nonmetals which upon irradiation do not produce products capable of sustained emission of radiation which would unacceptably interfere with the gamma radiation of 75Selenium. A further gamma radiation source comprises 75Selenium wherein the 75Selenium is provided in the form of compounds, alloys or mixtures with one or more metals or nonmetals, the neutron irradiation of which does produce products capable of sustained emission of radiation which would acceptably complement the gamma radiation of 75Selenium. Further, the gamma radiation source may have components that are separately irradiated before being combined and the components may be of natural isotopic composition or of isotopically modified composition so that the subsequent radiation peaks may also be adjusted in relative frequency.Type: ApplicationFiled: December 5, 2012Publication date: November 14, 2013Inventors: John J. Munro, III, Kevin J. Schehr
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Patent number: 8444544Abstract: A radiation modulator is used with a low energy source for breast brachytherapy using a balloon-like catheter. The clinical evaluation of the patient determines the modulator's optimal configuration so as to produce a non-uniform dose distribution to avoid healthy tissue. This modulation may range from a few percent to many tens of percent. A modulating member having predetermined dimensions and materials, i.e., length, width, thickness, is attached to a catheter in close proximity to the intended location of the radioactive source. The modulating member, for example, may be shaped as a rectangular plate, an oval plate or such and be attachable to a catheter.Type: GrantFiled: September 3, 2009Date of Patent: May 21, 2013Inventor: John J. Munro, III
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Patent number: 8357316Abstract: One gamma radiation source comprises 75Selenium or a precursor thereof, wherein the 75Selenium is provided in the form of one or more thermally stable compounds, alloys or mixtures with one or more nonmetals which upon irradiation do not produce products capable of sustained emission of radiation which would unacceptably interfere with the gamma radiation of 75Selenium. A further gamma radiation source comprises 75Selenium or a precursor thereof, wherein the 75Selenium is provided in the form of one or more thermally stable compounds, alloys or mixtures with one or more metals or nonmetals, the neutron irradiation of which does produce products capable of sustained emission of radiation which would acceptably complement the gamma radiation of 75Selenium.Type: GrantFiled: September 28, 2009Date of Patent: January 22, 2013Inventors: John J. Munro, III, Kevin J. Schehr
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Publication number: 20130009120Abstract: Manufacturing a gamma radiation source includes providing an unacceptable material that is a combination of acceptable and unacceptable isotopes, transforming the unacceptable material into an acceptable material by removing unacceptable isotopes from the unacceptable material, leaving only acceptable isotopes, mixing selenium-74 and the acceptable material and heating the mixture to cause the constituents to inter-react and subsequently subjecting the reaction product to irradiation to convert at least a proportion of the selenium-74 to selenium-75. Manufacturing a gamma radiation source may also include adding at least one other acceptable material to the mixture. The at least one other acceptable material may be added to the mixture prior to heating the mixture. The unacceptable material may be selected from the group consisting of: Zinc, Titanium, Nickel, Zirconium, Ruthenium, Iron, Silver, Indium, Thallium, Samarium, Ytterbium, Germanium, and Iridium.Type: ApplicationFiled: June 25, 2012Publication date: January 10, 2013Inventors: John J. MUNRO, III, Kevin J. SCHEHR
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Publication number: 20120292369Abstract: A staple delivery applicator for delivering radioactive staples during brachytherapy medical treatment has an actuating device for at source staples located distally from the actuating device. The actuating device is removably attachable to an actuator arm on a proximal end. A staple applicator cartridge holder is attached to the actuator arm on a distal end. The staple applicator cartridge is mountable in the holder and having a plurality of slots for mounting of radioactive source staples therein. An anvil therein crimps the staples. The staple applicator cartridge holder is removably mountable in a connector and the connector is also removably mounted to a surgical staple holder. A trigger device being one of the actuating devices has a control for closing the anvil of the cartridge holder and for firing of the source staples in the cartridge therein to cause the staples to crimp, and a control for opening the anvil and releasing the trigger device from the actuator arm.Type: ApplicationFiled: May 16, 2011Publication date: November 22, 2012Inventors: John J. Munro, III, Kevin Schehr, Krissie K. Zambrano, Matthew Hollows
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Publication number: 20110073815Abstract: One gamma radiation source comprises 75Selenium or a precursor thereof, wherein the 75Selenium is provided in the form of one or more thermally stable compounds, alloys or mixtures with one or more nonmetals which upon irradiation do not produce products capable of sustained emission of radiation which would unacceptably interfere with the gamma radiation of 75Selenium. A further gamma radiation source comprises 75Selenium or a precursor thereof, wherein the 75Selenium is provided in the form of one or more thermally stable compounds, alloys or mixtures with one or more metals or nonmetals, the neutron irradiation of which does produce products capable of sustained emission of radiation which would acceptably complement the gamma radiation of 75Selenium.Type: ApplicationFiled: September 28, 2009Publication date: March 31, 2011Inventor: John J. Munro, III
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Patent number: 7530941Abstract: Radioactive sources are manufactured for treating a tumor or cancerous area occurring around a conduit or duct in the body by emitting X-rays to destroy or reduce the tumors. The sources contain ytterbium which is substantially enriched in 168Ytterbium and which is activated by exposure to neutron flux so as to contain a minor, but significant, fraction of X-ray and gamma-emitting 169Ytterbium. The radioactive 169Ytterbium source is inserted through a catheter or applicator or needle to the site of the cancer where it is maintained in position for a period of time to reduce the occurrence of cancer. The ytterbium also acts as an X-ray-opaque marker to facilitate external visualization of the sources during their delivery to the treatment site. The sources are encased in a shell to prevent direct contact of the radioactive material with human tissue. This encapsulation may be formed by welding a pair of end caps to a tubular member.Type: GrantFiled: February 2, 2004Date of Patent: May 12, 2009Assignee: Best Medical International, Inc.Inventors: John J. Munro, III, Matthew R. Hollows
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Patent number: 7276716Abstract: A radiation protection system for shielding medical personnel from a gamma ray source being used to provide brachytherapy to a patient is provided by disposing shielding material between the source of radiation and locations outside the radiation protection system in such a manner as to provide shielding for the primary radiation in directions from which radiation from the source may emerge, while providing the patient an open viewing area with a large field of view for the patient to view the locations outside the radiation protection system. The described system reduces the radiation exposure of staff in the treatment room, thereby permitting physicians and therapists to observe the patient without being exposed to excessive amounts of radiation. The opening in the radiation protection system around the head of the patient provides the ability for the patient to see his surroundings and to eliminate the anxiety resulting from the feeling of being closed in.Type: GrantFiled: November 24, 2004Date of Patent: October 2, 2007Assignee: Implant Sciences CorporationInventor: John J. Munro, III
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Patent number: 6709381Abstract: A system for brachytherapy is provided. The system includes an implantation device having a tubular member, a radioactive source within the member, and a socket at opposing ends of the tubular member. A plurality of implantation devices may be joined into an assembly by use of a spacer positioned within the sockets of adjoining devices. The device may be deployed at an implantation site by use of a delivery mechanism, such as needle. The presence of the tubular members and spacers minimizes movement of the radioactive source subsequent to deployment, so as not to alter dose distribution for subsequent irradiation.Type: GrantFiled: May 31, 2002Date of Patent: March 23, 2004Assignee: Implant Sciences CorporationInventor: John J. Munro, III
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Patent number: 6527693Abstract: This application relates to devices and methods for locally delivering therapeutic radiation to tissue in the body of a patient. In certain embodiments, the subject devices are implanted into a cavity in the patient left by surgical removal of tumorous tissue or other diseased tissue, to deliver radiation to the tissue surrounding the cavity. In certain embodiments, the devices are elastic or can otherwise be shaped to conform to the shape of the cavity in the patient.Type: GrantFiled: January 30, 2001Date of Patent: March 4, 2003Assignee: Implant Sciences CorporationInventors: John J. Munro, III, Anthony J. Armini