Abstract: A twist lock mount for quick mounting and positioning a device to a support includes a mount receiving member attachable to or integral with the support and a mounting member attachable to or integral with a device to be mounted. The receiving member provides a channel covered by flanges that further define a narrower channel or slot. The mounting member is configured to slide into the channel when it is in one rotational orientation and to lock securely into place when it is in another. A rotation in the opposite direction will unlock the device so that the mount can be slid out of the channel quickly and easily. The twist lock mount simply and effectively prevents movement in the longitudinal, transverse and axial directions and is well suited for use in harsh, high vibration environments.