Patents by Inventor John J. Plattner

John J. Plattner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Renin inhibiting compounds
    Patent number: 4652551
    Abstract: The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is an N-protecting group; n is 0 or 1; B is hydrogen, hydroxy, NH, loweralkyl or arylalkyl; with the proviso that when A is an N-protecting group, B is NH and when n is 0, B is hydrogen, hydroxyl, loweralkyl or arylalkyl; R.sub.1, R.sub.3 and R.sub.5 are loweralkyl or hydrophilic, lipophilic or aromatic amino acid side chains and may be the same or different; R.sub.2, R.sub.4, R.sub.7, R.sub.8 and R.sub.9 are hydrogen or loweralkyl and may be the same or different; X is CH.sub.2 ; R.sub.6 is loweralkyl, cycloalkyl, cycloalkylalkyl, aryl or arylalkyl; and X and R.sub.6 when taken together may be a vinylic group.
    Type: Grant
    Filed: May 17, 1985
    Date of Patent: March 24, 1987
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, John J. Plattner, Joseph F. Dellaria
  • Renin inhibiting compounds
    Patent number: 4645759
    Abstract: The invention relates to renin inhibiting compounds of the formula ##STR1## wherein A is an N-protecting group; n is 0 or 1; B is hydrogen, hydroxy, NH, loweralkyl or arylalkyl; with the proviso that when A is an N-protecting group, B is NH and when n is 0, B is hydrogen, hydroxy, loweralkyl or arylalkyl; R.sub.1, R.sub.3 and R.sub.5 are loweralkyl or hydrophilic, lipophilic or aromatic amino acid side chains and may be the same or different; R.sub.2, R.sub.4, R.sub.7, R.sub.8 and R.sub.9 are hydrogen or loweralkyl and may be the same or different; X is NH, O, S, SO or SO.sub.2 ; and R.sub.6 is loweralkyl, cycloalkyl, cycloalkylalkyl, aryl, arylalkyl or an N-protecting group, with the proviso that R.sub.6 may be an N-protecting group when X is NH.
    Type: Grant
    Filed: May 17, 1985
    Date of Patent: February 24, 1987
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, John J. Plattner, Joseph F. Dellaria