Patents by Inventor John J. Spaltro

John J. Spaltro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Injectable Depot Compositions and Uses Thereof
    Publication number: 20130108681
    Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patients body surface by injection.
    Type: Application
    Filed: August 23, 2012
    Publication date: May 2, 2013
    Inventors: Guohua Chen, Paul R. Houston, Lothar Walter Kleiner, John J. Spaltro
  • Injectable depot compositions and uses thereof
    Patent number: 8252303
    Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: August 28, 2012
    Assignee: Durect Corporation
    Inventors: Guohua Chen, Paul R. Houston, Lothar Walter Kleiner, John J. Spaltro
  • Catheter injectable depot compositions and uses thereof
    Publication number: 20110046606
    Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
    Type: Application
    Filed: October 18, 2010
    Publication date: February 24, 2011
    Inventors: Guohua Chen, Paul R. Houston, Lothar Kleiner, John J. Spaltro
  • Injectable depot compositions and uses thereof
    Publication number: 20040024069
    Abstract: Injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having a miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.
    Type: Application
    Filed: November 14, 2002
    Publication date: February 5, 2004
    Inventors: Guohua Chen, Paul R. Houston, Lothar Walter Kleiner, John J. Spaltro