Patents by Inventor John J. Tegeler

John J. Tegeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (1,2,4-Oxadiazol-3-yl)arylmethanones, compositions and pharmaceutical use
    Patent number: 4562186
    Abstract: There are disclosed novel compounds having the formula ##STR1## where X is hydrogen, halogen (F, Cl, Br or I), loweralkyl or loweralkoxy; and R is --CH, --CONH.sub.2, --COOCH(CH.sub.3).sub.2, --COOH, --COO(CH.sub.2).sub.4 Cl, ##STR2## R.sub.1 and R.sub.2 being independently hydrogen or lower alkyl and R.sub.3 being ##STR3## an optical antipode thereof or a pharmaceutically acceptable acid addition salt thereof, which are useful as antihypertensive, analgesic and antiinflammatory agents, methods for synthesizing them, and pharmaceutical compositions comprising an effective amount of such a compound.
    Type: Grant
    Filed: January 22, 1985
    Date of Patent: December 31, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: John J. Tegeler, Craig J. Diamond
  • (Isoxazol-3-yl)arylmethanones, compositions and pharmaceutical use
    Patent number: 4562187
    Abstract: There are disclosed novel compounds having the formula ##STR1## where each X is independently hydrogen, halogen (F, Cl, Br or I), loweralkyl or loweralkoxy; m is 1 or 2; R' is hydrogen or loweralkyl; and R is ##STR2## n being 1, 2 or 3, each of R.sub.1 and R.sub.2 being independently hydrogen or loweralkyl and R.sub.3 being ##STR3## an optical antipode thereof or a pharmaceutically acceptable acid addition salt thereof, which are useful as antihypertensive, analgesic and antiinflammatory agents, methods for synthesizing them, and pharmaceutical compositions comprising an effective amount of such a compound.
    Type: Grant
    Filed: January 22, 1985
    Date of Patent: December 31, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: John J. Tegeler, Craig J. Diamond
  • Isoxazole intermediates
    Patent number: 4544753
    Abstract: This invention relates to substituted 8-phenylisoxazolo[4,3-e][1,4]diazepin-5-ones of the formula ##STR1## wherein R is lower alkyl; R.sub.1 is hydrogen, amino alkyl, propargyl and lower alkyl; X is oxygen and sulfur; and Y is halogen, trifluoromethyl, lower alkyl, lower alkoxy and hydrogen. The compounds of this invention display useful anxiolytic and anticonvulsant activities.
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: October 1, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Incorporated
    Inventors: John J. Tegeler, Craig J. Diamond
  • Substituted 8-phenylisoxazolo[4,3-e][1,4]diazepin-5-ones
    Patent number: 4514410
    Abstract: This invention relates to substituted 8-phenylisoxazolo[4,3-e][1,4]diazepin-5-ones of the formula ##STR1## wherein R is lower alkyl; R.sub.1 is hydrogen, amino alkyl, propargyl and lower alkyl; X is oxygen and sulfur; and Y is halogen, trifluoromethyl, lower alkyl, lower alkoxy and hydrogen. The compounds of this invention display useful anxiolytic and anticonvulsant activites.
    Type: Grant
    Filed: May 31, 1984
    Date of Patent: April 30, 1985
    Assignee: Hoechst-Roussel Pharmaceuticals Inc.
    Inventors: John J. Tegeler, Craig J. Diamond