Patents by Inventor John J. Urh

John J. Urh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gradient liquid chromatography enhancement system
    Publication number: 20080047899
    Abstract: An isocratic gradient profile is inserted into a gradient profile during a flash chromatographic run when TLC indicates that it will be difficult to separate the component being purified from its closest impurity by a gradient. TLC is utilized to determine at least two retention factors with two significantly different solvent strengths for the same solvent system. The two or more retention factors are used to determine a solvent strength in which the retention factor of a target component and the retention factor of a closest impurity are within 0.8 of each other. The isocratic gradient profile is started when this solvent strength is reached during the gradient chromatographic run.
    Type: Application
    Filed: August 23, 2006
    Publication date: February 28, 2008
    Applicant: Teledyne Isco, Inc.
    Inventors: Dale A. Davison, Mikael E. Mahler, Veronica D. Thomason, John J. Urh, David Trail