Patents by Inventor John J. Wixted

John J. Wixted has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210145355
    Abstract: In some embodiments, there is provide a method of analysing a bone fracture, comprising; stabilizing a bone having a fracture including a first support point located distal of the fracture and a second support point located proximal of the fracture; applying a force to an area of the bone having the fracture to cause a displacement of the fracture; imaging the bone during the application of force thereto; and comparing the image of the bone during the application of force to an image of the bone without the application of force to determine the state of the fracture.
    Type: Application
    Filed: January 27, 2021
    Publication date: May 20, 2021
    Inventors: Karen L. Troy, John J. Wixted, Ara Nazarian
  • Patent number: 10945658
    Abstract: In some embodiments, there is provide a method of analysing a bone fracture, comprising; stabilizing a bone having a fracture including a first support point located distal of the fracture and a second support point located proximal of the fracture; applying a force to an area of the bone having the fracture to cause a displacement of the fracture; imaging the bone during the application of force thereto; and comparing the image of the bone during the application of force to an image of the bone without the application of force to determine the state of the fracture.
    Type: Grant
    Filed: April 19, 2018
    Date of Patent: March 16, 2021
    Assignees: Worcester Polytechnic Institute, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Karen L. Troy, John J. Wixted, Ara Nazarian
  • Publication number: 20180303408
    Abstract: In some embodiments, there is provide a method of analysing a bone fracture, comprising; stabilizing a bone having a fracture including a first support point located distal of the fracture and a second support point located proximal of the fracture; applying a force to an area of the bone having the fracture to cause a displacement of the fracture; imaging the bone during the application of force thereto; and comparing the image of the bone during the application of force to an image of the bone without the application of force to determine the state of the fracture.
    Type: Application
    Filed: April 19, 2018
    Publication date: October 25, 2018
    Inventors: Karen L. Troy, John J. Wixted, Ara Nazarian
  • Publication number: 20120253345
    Abstract: Advances in our understanding of the cellular mechanisms underlying skeletal regeneration have not been effectively translated in vivo treatment because non-invasive monitoring of bone fracture healing is limited to imaging technology (i.e., for example, x-rays) that cannot be quantified and are subjectively interpreted. The method disclosed herein assesses rates of hip fracture healing using a strain gauge device implanted into a standard orthopedic implant. It has been demonstrated that such a device can measure differences between intact and partially osteotomized fracture models (p<0.05) and that the device can distinguish between stable and unstable fracture patterns in completely osteotomized models across a physiologic range of loads. Such devices are compatible with in vivo bone fracture healing methods, wherein the device is placed onto an orthopedic implant and the strain data is transmitted on a real time basis, thereby providing a non-invasive quantification of bone fracture repair rates.
    Type: Application
    Filed: October 6, 2010
    Publication date: October 4, 2012
    Inventor: John J. Wixted
  • Publication number: 20110021560
    Abstract: The present invention is related to the field of cartilage physiology, repair, and regeneration. In particular, the invention contemplates a treatment for bone healing disorders, especially those related to the articular joints and bone, by upregulating chondrocyte proliferation. For example, inhibition of cysteinyl leukotriene activity on chondrocytes by using cysteinyl leukotriene-1 receptor antagonists may be useful in preventing and treating bone healing disorders.
    Type: Application
    Filed: June 23, 2010
    Publication date: January 27, 2011
    Inventors: Paul Joseph Fanning, John J. Wixted