Patents by Inventor John Janusz

John Janusz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treating anemia
    Patent number: 11857543
    Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.
    Type: Grant
    Filed: June 4, 2014
    Date of Patent: January 2, 2024
    Assignee: Akebia Therapeutics, Inc.
    Inventors: Robert Shalwitz, Charlotte Hartman, Akshay Buch, Isaiah Shalwitz, John Janusz, Joseph Gardner
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20220274976
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: March 3, 2022
    Publication date: September 1, 2022
    Inventors: Kevin PETERS, Robert SHALWITZ, John JANUSZ, Alexander SMITH
  • HPTP-BETA INHIBITORS
    Publication number: 20210130341
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed.
    Type: Application
    Filed: October 2, 2020
    Publication date: May 6, 2021
    Inventors: John Janusz, James Copp, Kevin Peters
  • HPTP-Beta inhibitors
    Patent number: 10858354
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: December 8, 2020
    Assignee: Aerpio Pharmaceuticals, Inc.
    Inventors: John Janusz, James Copp, Kevin Peters
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20200361926
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: May 29, 2020
    Publication date: November 19, 2020
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • Probiotic Bacterial Strains That Produce Short Chain Fatty Acids And Compositions Comprising Same
    Publication number: 20200345791
    Abstract: Disclosed herein are probiotic bacterial strains or species that produce short chain fatty acids (SCFA), such as butyrate, and compositions comprising the same. The bacterial strains or compositions prepared thereby are used in preparing food, supplements, compositions, and other consumables to provide health benefits, including therapeutic applications, for a variety of disorders, including metabolic, immune, intestinal, and inflammatory disorders. Thus, also disclosed herein are methods of treating a subject suffering from a disorder, such as a metabolic disorder, an immune disorder, an intestinal disorder, or an inflammatory disorder with a composition comprising the probiotic bacterial strains or species disclosed herein. Uses of a bacterial strain or species and a composition comprising them provided in a nutritional product or medicament to improve health or prevent or treat a variety of disorders in a subject are also disclosed.
    Type: Application
    Filed: April 28, 2020
    Publication date: November 5, 2020
    Inventors: Michael John Janusz, Anna Malgorzata Plechaty
  • BIFIDOBACTERIUM LONGUM
    Publication number: 20200115685
    Abstract: A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
    Type: Application
    Filed: November 8, 2019
    Publication date: April 16, 2020
    Applicant: Alimentary Health Ltd.
    Inventors: Jose Carlos GARCIA-GARCIA, Michael John Janusz, Barry Kiely, Eileen Frances Murphy, Liam O'Mahony
  • Patent number: 10519430
    Abstract: A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: December 31, 2019
    Assignee: Alimentary Health Ltd.
    Inventors: Jose Carlos Garcia-Garcia, Michael John Janusz, Barry Kiely, Eileen Frances Murphy, Liam O'Mahony
  • Bifidobacterium longum
    Publication number: 20190153408
    Abstract: A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
    Type: Application
    Filed: February 4, 2019
    Publication date: May 23, 2019
    Inventors: Jose Carlos Garcia-Garcia, Michael John Janusz, Barry Kiely, Eileen Frances Murphy, Liam O'Mahony
  • Patent number: 10233433
    Abstract: A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: March 19, 2019
    Assignees: Alimentary Health Ltd., The Procter & Gamble Company
    Inventors: Jose Carlos Garcia-Garcia, Michael John Janusz, Barry Kiely, Eileen Frances Murphy, Liam O'Mahony
  • HPTP-BETA INHIBITORS
    Publication number: 20180354937
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed.
    Type: Application
    Filed: May 7, 2018
    Publication date: December 13, 2018
    Inventors: John Janusz, James Copp, Kevin Peters
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180251457
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: May 2, 2018
    Publication date: September 6, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237430
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237431
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180237429
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 20, 2018
    Publication date: August 23, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • HPTP-? inhibitors
    Patent number: 9994560
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: June 12, 2018
    Assignee: AERPIO THERAPEUTICS, INC.
    Inventors: John Janusz, James Copp, Kevin Peters
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20180022741
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: February 27, 2017
    Publication date: January 25, 2018
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • Bifidobacterium longum
    Publication number: 20170058270
    Abstract: A formulation comprising an ingestible carrier and an isolated strain of Bifidobacterium longum.
    Type: Application
    Filed: August 26, 2016
    Publication date: March 2, 2017
    Inventors: Jose Carlos Garcia-Garcia, Michael John Janusz, Barry Kiely, Eileen Frances Murphy, Liam O'Mahony
  • Compositions, formulations and methods for treating ocular diseases
    Patent number: 9440963
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 13, 2016
    Assignee: AERPIO THERAPEUTICS, INC.
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith
  • COMPOSITIONS, FORMULATIONS AND METHODS FOR TREATING OCULAR DISEASES
    Publication number: 20160220540
    Abstract: Disclosed herein are compounds effective for activation of Tie-2 and inhibition of HPTP-beta. The compounds can provide effective therapy for conditions associated with angiogenesis, for example, ocular conditions. Formulations for increased solubility are disclosed. Combination therapy with antibodies and PK/PD data are also disclosed.
    Type: Application
    Filed: April 14, 2016
    Publication date: August 4, 2016
    Inventors: Kevin Peters, Robert Shalwitz, John Janusz, Alexander Smith