Patents by Inventor John Jay Gargus

John Jay Gargus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEFECTIVE CALCIUM SIGNALING AS A TOOL IN AUTISM SPECTRUM DISORDERS
    Publication number: 20240159774
    Abstract: Methods of detecting the level of inositol trisphosphate receptor (IP3R) free calcium (Ca2+) signaling activity in the cultured cells induced by an agonist of IP3R Ca2+ signaling are described herein. The detection of IP3R Ca2+ signaling allows for diagnosing the risk of a patient or subject for developing an Autism Spectrum Disorder (ASD). Additionally, methods described herein could be used for identifying potential therapeutic anti-ASD agents. The methods for treatment and monitoring of the disease are also outlined.
    Type: Application
    Filed: January 24, 2024
    Publication date: May 16, 2024
    Inventors: John Jay Gargus, Galina Schmunk, Ian Parker, Ian Smith
  • DEFECTIVE CALCIUM SIGNALING AS A TOOL IN AUTISM SPECTRUM DISORDERS
    Publication number: 20210033625
    Abstract: The present invention features methods of detecting the level of inositol trisphosphate receptor (IP3R) free calcium (Ca2+) signaling activity in the cultured cells induced by an agonist of IP3R Ca2+ signaling. The detection of IP3R Ca2+ signaling allows for diagnosing the risk of a patient or subject for developing an Autism Spectrum Disorder (ASD). Additionally, methods described herein could be used for identifying potential therapeutic anti-ASD agents. The methods for treatment and monitoring of the disease are also outlined.
    Type: Application
    Filed: October 12, 2020
    Publication date: February 4, 2021
    Inventors: John Jay Gargus, Galina Schmunk, Ian Parker, Ian Smith
  • Defective calcium signaling as a tool in autism spectrum disorders
    Patent number: 10802029
    Abstract: The present invention features methods that allow for diagnosing a risk for a patient or subject developing an Autism Spectrum Disorder, for identifying potentially therapeutic anti-ASD agents, and methods for treatment monitoring as specified in the independent claims.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: October 13, 2020
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: John Jay Gargus, Galina Schmunk, Ian Parker, Ian Smith
  • DEFECTIVE CALCIUM SIGNALING AS A TOOL IN AUTISM SPECTRUM DISORDERS
    Publication number: 20190128898
    Abstract: The present invention features methods that allow for diagnosing a risk for a patient or subject developing an Autism Spectrum Disorder, for identifying potentially therapeutic anti-ASD agents, and methods for treatment monitoring as specified in the independent claims.
    Type: Application
    Filed: December 18, 2018
    Publication date: May 2, 2019
    Inventors: John Jay Gargus, Galina Schmunk, Ian Parker, Ian Smith