Abstract: The present invention concerns a method and equipment for drilling bone, in particular for setting a pedicle screw using a manual or motorized drilling tool, said equipment comprising a drilling instrument, a source of electric impulses and means for connecting the electric impulse source to the drilling instrument. The equipment comprises at least one sensor for detecting a muscle signal intended to be implanted in a muscle or placed on the skin in the vicinity of a muscle before starting drilling and during drilling, and means for producing an alert in the event of detection by at least one sensor of a muscle signal correlated with the source of electric impulses connected to the drilling instrument.